高原低氧环境气虚小鼠心、肺反应性变化的分子机制研究(2)
基金项目：甘肃省科技支撑计划(1204FKCA169)；国家科技支撑计划(2011BAI05B02)；敦煌医学与转化省部共建教育部重点实验室开放基金(DHYX1213-012)通讯作者：刘永琦，E-mail：liuyongqi73@163.com
Also the gene expression of AQP-5 in lung increased obviously (P<0.01). Conclusion Long time exposure in high altitude hypoxia environment can cause qi deficiency and low pulmonary ventilation. Impaired myocardium may be related to the changes of Na+-K+-ATPase activity. The increase of expressions of HIF-1α in heart and lung and AQP-5 in lung may be beneficial to adaptive compensatory reaction of heart and lung.
Key words：high altitude hypoxia exposure；qi deficiency；LDH；Na+-K+-ATPase；HIF-1α；AQP-5；mice
高原反应发病急、病程短、危险性大 ......
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