基金项目：国家自然科学基金(81574004)；湖南省中医药管理局课题(201408)

    通讯作者：卢敏，E-mail：lumin6563@163.com

    inflammatory factors of the joint fluid and inhibit the Wnt signal pathway through regulating the expression of Sox9 and Collagen Ⅱ in the pathway， which can promote the cell proliferation of knee osteoarthritis's cartilage corpuscle and benefit the repairment of cartilage corpuscle in order to relieve pains and improve functions of knee joint.

    Keywords： modified Duhuo Jisheng Mixture； knee osteoarthritis； repairment of cartilage corpuscle

    膝骨关节炎(knee osteoarthritis ......