刮痧对健康机体抗氧化和免疫功能的影响(1)
摘要：目的 测定刮痧前后不同时段健康机体的超氧化物歧化酶(SOD)、丙二醛(MDA)、过氧化脂质(LPO)、胆红素、白细胞介素(IL)-1、IL-6含量，探讨刮痧对健康机体抗氧化和免疫功能的影响。方法 选择健康受试者12名，用刮痧板沿左侧膀胱经自心俞至肾俞由上向下刮拭出痧。于刮痧前及刮痧后即刻、6 h、24 h手臂静脉无菌采血3 mL，测定血清中SOD、MDA、LPO、总胆红素、IL-1、IL-6含量。结果 与刮痧前比较，刮痧后即刻SOD含量上升，MDA、LPO含量下降；刮痧后6 h SOD、MDA含量下降，LPO含量上升；刮痧后24 h SOD含量下降，MDA、LPO含量上升。与刮痧前比较，刮痧后即刻、刮痧后6 h胆红素含量下降，刮痧后24 h胆红素含量升高。与刮痧前比较，刮痧后即刻IL-1含量降低、IL-6含量升高；刮痧后6、24 h，IL-1、IL-6含量降低。结论 对于健康人群，刮痧可通过改变机体清除氧自由基与过氧化物能力及机体免疫功能相关活性物质的含量，调节机体抗氧化作用和免疫功能。
关键词：刮痧；抗氧化；免疫功能；健康机体
DOI：10.3969/j.issn.1005-5304.2018.12.009
中图分类号：R244.4 文献标识码：A 文章编号：1005-5304(2018)012-0032-03
Abstract： Objective To detect the contents of SOD， MDA， LPO， bilirubin， IL-1 and IL-6 in healthy human body during different periods before and after Guasha therapy； To study the effects of Guasha therapy on anti-oxidation and immunity functions of human body. Methods Totally 12 healthy objects were skin scraped with Guasha plate along the left side of bladder meridian from acupoint Xinshu to acupoint Shenshu until the blood under skin was shown. 3 mL arm vein sterile blood was drawn before Guasha therapy and 0 h， 6 h， and 24 h after Guasha therapy. Then， the contents of SOD， LPO， MDA， bilirubin， IL-6 and IL-1 in the blood samples were tested. Results Compared with before Guasha therapy， the contents of SOD increased and MDA， LPO decreased； the contents of SOD and MDA decreased and LPO increased 6 h after Guasha therapy； the contents of SOD decreased and MDA and LPO increased 24 h after Guasha therapy. Compared with before Guasha therapy， the contents of bilirubin decreased 6 h after Guasha therapy， while the content of bilirubin increased 24 h after Guasha therapy. Compared with before Guasha therapy， the contents of IL-1 decreased and IL-6 increased after Guasha therapy immediately； the contents of IL-1 and IL-6 decreased 6 h and 24 h after Guasha therapy. Conclusion For healthy human beings， Guasha therapy can regulate anti-oxidation and immunity functions by changing the body ability to remove oxygen free radicals and peroxide and the content of body’s immune function related active material.
Keywords： Guasha therapy； anti-oxidation； immunity functions； healthy human body
刮痧療法是用特制的刮痧器具，依据中医经络腧穴理论，在体表进行相应的手法刮拭以防治疾病的中医外治法[1]。古代医家认为，刮痧法的作用机理为开腠理、行气血、通经络、散邪毒[2]。现代研究表明，刮痧可促进局部微循环，改善组织新陈代谢[3]，提高机体抗氧化能力和免疫功能，起到预防保健作用[4]。本研究通过观察健康机体刮痧前后外周血中超氧化物歧化酶(SOD)、丙二醛(MDA)、过氧化脂质(LPO)、胆红素、白细胞介素(IL)-1、IL-6含量变化，探讨刮痧对健康机体抗氧化、免疫功能的影响。现报道如下。
1 资料与方法
1.1 一般资料, 百拇医药(王莹莹 陈虹 张豪斌 徐东升 杨莉 杨金生)
关键词：刮痧；抗氧化；免疫功能；健康机体
DOI：10.3969/j.issn.1005-5304.2018.12.009
中图分类号：R244.4 文献标识码：A 文章编号：1005-5304(2018)012-0032-03
Abstract： Objective To detect the contents of SOD， MDA， LPO， bilirubin， IL-1 and IL-6 in healthy human body during different periods before and after Guasha therapy； To study the effects of Guasha therapy on anti-oxidation and immunity functions of human body. Methods Totally 12 healthy objects were skin scraped with Guasha plate along the left side of bladder meridian from acupoint Xinshu to acupoint Shenshu until the blood under skin was shown. 3 mL arm vein sterile blood was drawn before Guasha therapy and 0 h， 6 h， and 24 h after Guasha therapy. Then， the contents of SOD， LPO， MDA， bilirubin， IL-6 and IL-1 in the blood samples were tested. Results Compared with before Guasha therapy， the contents of SOD increased and MDA， LPO decreased； the contents of SOD and MDA decreased and LPO increased 6 h after Guasha therapy； the contents of SOD decreased and MDA and LPO increased 24 h after Guasha therapy. Compared with before Guasha therapy， the contents of bilirubin decreased 6 h after Guasha therapy， while the content of bilirubin increased 24 h after Guasha therapy. Compared with before Guasha therapy， the contents of IL-1 decreased and IL-6 increased after Guasha therapy immediately； the contents of IL-1 and IL-6 decreased 6 h and 24 h after Guasha therapy. Conclusion For healthy human beings， Guasha therapy can regulate anti-oxidation and immunity functions by changing the body ability to remove oxygen free radicals and peroxide and the content of body’s immune function related active material.
Keywords： Guasha therapy； anti-oxidation； immunity functions； healthy human body
刮痧療法是用特制的刮痧器具，依据中医经络腧穴理论，在体表进行相应的手法刮拭以防治疾病的中医外治法[1]。古代医家认为，刮痧法的作用机理为开腠理、行气血、通经络、散邪毒[2]。现代研究表明，刮痧可促进局部微循环，改善组织新陈代谢[3]，提高机体抗氧化能力和免疫功能，起到预防保健作用[4]。本研究通过观察健康机体刮痧前后外周血中超氧化物歧化酶(SOD)、丙二醛(MDA)、过氧化脂质(LPO)、胆红素、白细胞介素(IL)-1、IL-6含量变化，探讨刮痧对健康机体抗氧化、免疫功能的影响。现报道如下。
1 资料与方法
1.1 一般资料, 百拇医药(王莹莹 陈虹 张豪斌 徐东升 杨莉 杨金生)