基于NALP3炎性体的痛风宁对急性痛风性关节炎大鼠抗炎作用量效和时效研究(2)
with the model group, the contents of IL-1β and PGE2, and the expressions of NALP3, ASC, Caspase-1 protein and mRNA significantly decreased in Tongfengning medium- and high-dosage groups at each time point (P<0.01, P<0.01); Compared with the colchicine group, the contents of IL-1β and PGE2, and the expressions of NALP3, ASC, Caspase-1 protein and mRNA were not significantly different in the Tongfengning medium- and high-dosage groups at each time point (P>0.05) ......
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