肺肾同治法治疗IgA肾病(1)

http://www.100md.com 2020年3月1日 《中国中医药信息杂志》 20203

     摘要：目前，我國IgA肾病(IgA nephropathy，IgAN)占肾活检病例40%～50%，其中50%患者会进展至终末期肾病。中医认为，“本虚标实”是IgAN主要病机。先天禀赋不足，饮食内伤，导致肺气失宣，卫外不固，外邪内侵，内归于肾，终致IgAN发生。据此，本文提出肺肾同治的思路：①益肺气以固护卫表，溯本清源;②宣肺气以祛风清解，阻邪内扰;③利肾邪以澄流复旧。以此既对疾病上游黏膜免疫，又针对下游肾脏免疫炎性反应，进行系统干预，可奏溯本清源、澄流复旧之功。

    关键词：肺肾同治;IgA肾病

    中图分类号：R272.969.26 文献标识码：A 文章编号：1005-5304(2020)03-0118-04

    DOI：10.3969/j.issn.1005-5304.201907456

Treatment of IgA Nephropathy with Simultaneously Treating Lung-kidney Therapy

GAO Xiangfeng1，2， RAO Xiangrong2， LI Shen2， CHENG Tingzhu1，2， FANG Lügui3， WANG Xiujuan3

1. Beijing University of Chinese Medicine， Beijing 100029， China; 2. Guang'anmen Hospital， China Academy of Chinese Medical Sciences， Beijing 100053， China; 3. Southern District of Guang'anmen Hospital， China Academy of Chinese Medical Sciences， Beijing 102618， China

    Abstract： At present， IgA nephropathy (IgAN) accounts for 40%–50% of renal biopsy cases in China， and 50% of them will progress to end-stage renal disease. TCM believes that the main pathogenesis of IgAN is “deficiency of origin and excess of symptoms”. Inadequate innate endowment and dietary injury lead to loss of lung qi， incomplete external defense， invasion of external pathogens and internal attribution to kidney， which ultimately lead to the occurrence of IgAN. In view of the above， this article put forward the idea of simultaneously treating lung and kidney：Benefiting lung qi to invigorate qi for strengthening superficies， tracing back to the source; Promoting the dispersing function of the lung to dispel wind and clear away evil and internal disturbance; Benefiting kidney to recover. In this way， we can not only immunize the upstream mucosa of the disease， but also intervene systemically in the immuno-inflammatory reaction of the downstream kidney， so as to trace the origin of the disease and recover the disease., 百拇医药(高向峰 饶向荣 李深 成庭柱 方吕贵 王秀娟)

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