基于多源数据库信息整合探讨银莱汤干预脑肠轴作用机制(3)
银莱汤干预脑肠轴的潜在靶标并不是以脑肠肽为主,而主要是与脑肠肽相关的酶,如Nitric oxide synthase、Nitric oxide synthase、Neutrophil collagenase、Catalase Pancreatic alpha-amylase、Beta-amylase、Peroxidase/catalase T、Superoxide dismutase、Maltase glucoamylase、Glutathione S-transferase P、Glutathione S-transferase Mu 1、Glutathione S-transferase Mu 2、Glutathione S-transferase 1等;其次是相关神经递质受体,如Sodium-dependent dopamine transporter、Dopamine D1 receptor、Vascular endothelial growth factor receptor 2、Sodium-dependent serotonin transporter、Dopamine receptor、Calcitonin receptor等;而干預的脑肠肽主要涉及Cholecystokinin、Peptide YY、Proenkephalin-A、Pro-opiomelanocortin (POMC-C)等 ......
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