【摘要】 目的 研究嗜酒对银屑病病情及治疗的影响。方法 将嗜酒组197例与不饮酒组183例进行临床比较,观察两者之间皮损类型、皮损分布情况、严重程度、复发频度及治疗效果的差别。结果 嗜酒组和不饮酒组比较,皮损类型前者混合型和斑块型病例较多(P<0.05和P<0.01),后者红斑型病例较多(P<0.01);皮损分布前者泛发性病例明显多于后者(P<0.05),而局限性病例显著少于后者(P<0.01);严重程度前者重度病例显著多于后者(P<0.01),轻度病例显著少于后者(P<0.01),两组中度病例数比例相近(P>0.05);复发频度前者常年不愈病例明显多于后者(P<0.01),而能间隔3～4年复发的病例前者明显少于后者(P<0.01),能保持5年及以上复发者前者显著少于后者(P<0.01)。治疗效果前者不及后者(P<0.05)。结论 嗜酒对银屑病的皮损类型、皮损分布情况、严重程度、复发频度及治疗效果均可产生不利影响。

    【关键词】 银屑病;嗜酒;不利影响

    【Abstract】 Objective To study the effect of drink abuse on the patient's condition and treatment of psoriasis.Methods The type,distribution,severity,frequency of recurrence and therapeutic effect of skin lesions in 197 drinkers(drinking group)and 183 non-drinker(non drinking group)were analyzed and compared.Results Mixed and plaque type of the drinking group were more than those of the non drinking group,while the psoriasis erythem was dominant in non drinking group;Generalized psoriasis in the formergroup was more than that in the later group and localized psoriasis was less than that in the latter group;There were more serious patients and less mild patients in the drinking group.With respect to recurrence,the former group had more patients who relapsed every year,and the patients who relapsed after 3～4 years were obviously less,and the patients who relapsed after 5 years or longer were significantly less than the latter group;The therapeutic effect of the latter group are better than that of the former group.Conclusion Drink abuse have adverse effect on the type,distribution,severity,recurrence and therapeutic effect of psoriatic lesion. ......