摘 要 血管加压素是一种由人体下丘脑合成的激素，在维持机体的渗透平衡、心血管功能和止血等方面发挥着重要作用。近年发现血管加压素相对不足是血管舒张性休克患者血流动力学不稳定的重要原因，而给予小剂量血管加压素(0.01～0.04 U/min)能显著提高平均动脉压、稳定循环功能、减少儿茶酚胺的用量、增加尿量、提高肾清除率，具有重要的临床应用价值。

    关键词 血管加压素 血管舒张性休克 治疗

    中图分类号：R972.5; R541.64 文献标识码：A 文章编号：1006-1533(2012)07-0004-04

    Application of vasopressin in the treatment of vasodilatory shock

    Han Xu-dong, Huang Xiao-ying

    (The Intensive Care Unit of the Third People’s Hospital of Nantong City, Nantong, 226006)

    Abstract Vasopressin is synthesized in the hypothalamus, which is crucial for osmoregulation, cardiovascular control, and homeostasis. Recent studies indicate that the relative vasopressin deficiency is an important reason of hemodynamic instability in patients with vasodilatory shock. Low dose vasopressin has an important value of clinical application in increasing the mean arterial pressure, improving the hemodynamic, reducing the dosage of catecholamines, and increasing the urine output and renal clearance rate. ......