摘 要 双相抑郁是双相障碍的一种发作形式，临床治疗困难。非典型抗精神病药物具有心境稳定作用，目前主要用于治疗双相躁狂，但对双相抑郁的治疗尚有争议。部分非典型抗精神病药物治疗双相抑郁有效。

    关键词 双相抑郁 非典型抗精神病药物 治疗

    中图分类号：R971.4 文献标识码：A 文章编号：1006-1533(2012)17-0007-03

    Atypical antipsychotics in the treatment of bipolar depression

    Wu Yan1,2, Yang Jie2, Shi Shen-xun2*

    (1. Shanghai Mental Health Center, School of Medicine, Shanghai Jiao Tong University, Shanghai 200030, China;

    2. Huashan Hospital, Fudan University, Shanghai 200040, China)

    Abstract Bipolar depression is a type of bipolar disorder which is hard to treat. Atypical antipsychotics, which have mood-stabilizing effect, are mainly used to treat bipolar mania, but their influence on bipolar depression remains controversial. Some atypical antipsychotics are effective in the treatment of bipolar depression.

    Key words bipolar depression; atypical antipsychotics; treatment

    双相障碍(bipolar disorder)是指既有躁狂或轻躁狂发作、又有抑郁发作的一类心境障碍 ......