无创性产前诊断技术应用于21—三体综合征筛查的进展(4)
[6] Hulten MA， Old RW. Non-invasive prenatal diagnosis of Down’s syndrome [J]. Lancet， 2007， 369(9578)： 1997.
[7] Chim SS， Jin S， Lee TY， et al. Systematic search for placental DNA methylation markers on chromosome 21：toward a maternal plasma-based epigenetic test for fetal trisomy 21[J]. Clin Chem， 2008， 54(3)： 500-511.
[8] Poon LL， Leung TN， Lau TK， et al. Presence of fetal RNA in maternal plasma[J]. Clin Chem， 2000， 46(11)： 1832-1834.
[9] United Kingdom National Screening Committee. Antenatal screening–working standards for Down’s syndrome screening 2007[EB/OL].(2012-01-30)[2013-01-30]. http：//fetalanomaly.screening.nhs.uk/standardsandpolicies.
[10] Sparks AB， Struble CA， Wang ET， et al. Noninvasive prenatal detection and selective analysis of cell-free DNA obtained from maternal blood： evaluation for trisomy 21 and trisomy 18[J]. Am J Obstet Gynecol， 2012， 206(4)： 319.
[11] Bishop AJ， Marteau TM， Armstrong D. Women and health care professionals’ preferences for Down’s syndrome screening tests： a conjoint analysis study[J]. BJOG， 2004， 111(8)： 775-779.
(收稿日期：2013-01-30)
, 百拇医药(周奋翮 孙路明)
[7] Chim SS， Jin S， Lee TY， et al. Systematic search for placental DNA methylation markers on chromosome 21：toward a maternal plasma-based epigenetic test for fetal trisomy 21[J]. Clin Chem， 2008， 54(3)： 500-511.
[8] Poon LL， Leung TN， Lau TK， et al. Presence of fetal RNA in maternal plasma[J]. Clin Chem， 2000， 46(11)： 1832-1834.
[9] United Kingdom National Screening Committee. Antenatal screening–working standards for Down’s syndrome screening 2007[EB/OL].(2012-01-30)[2013-01-30]. http：//fetalanomaly.screening.nhs.uk/standardsandpolicies.
[10] Sparks AB， Struble CA， Wang ET， et al. Noninvasive prenatal detection and selective analysis of cell-free DNA obtained from maternal blood： evaluation for trisomy 21 and trisomy 18[J]. Am J Obstet Gynecol， 2012， 206(4)： 319.
[11] Bishop AJ， Marteau TM， Armstrong D. Women and health care professionals’ preferences for Down’s syndrome screening tests： a conjoint analysis study[J]. BJOG， 2004， 111(8)： 775-779.
(收稿日期：2013-01-30)
, 百拇医药(周奋翮 孙路明)