摘 要 目的：探讨慢性乙肝合并肝硬化患者血清谷丙转氨酶(ALT)、乙肝表面抗原(HBsAg)水平与肝功能的相关性。方法：选取我院慢性乙型肝炎合并肝硬化患者215例，根据肝功能Child-Pugh分级将患者分为3组，其中A组(Child-Pugh A级)75例，B组(Child-Pugh B级)73例，C组(Child-Pugh C级)67例；全部患者均检测ALT、HBsAg水平。结果：A组ALT、HBsAg水平均明显低于B、C组，B组ALT、HBsAg水平均明显低于C组；且A组ALT异常率明显低于B、C组，B组ALT异常率明显低于C组。组间比较差异均具有显著性。结论：慢性乙肝合并肝硬化患者血清ALT、HBsAg与肝功能显著相关，ALT、HBsAg水平越低，肝功能受损程度越低。

    关键词 慢性乙肝 血清谷丙转氨酶 乙肝表面抗原 肝功能

    中图分类号：R512.62 文献标识码：B 文章编号：1006-1533(2015)07-0047-03

    ABSTRACT Objective： To investigate the correlation between the levels of serum alanine aminotransferase (ALT) and hepatitis B surface antigen(HBsAg) and the liver function in the patients with chronic hepatitis B and liver cirrhosis. Methods： Two hundred and fifteen cases of the patients in our hospital were selected and divided into three groups based on their Child-Pugh grade of liver function： group A (Child-Pugh grade A ......