临床药师参与中药注射剂合理应用的研究(1)
摘 要 目的：评价临床药师对中药注射剂合理使用进行干预的效果。方法：通过系统抽样方法，分别抽取2013年第4季度100份住院医嘱和2014年第4季度100份住院医嘱，分别作为对照组和研究组，对两组中药注射剂使用情况进行统计分析。结果：经临床药师干预后，研究组患者使用中药注射剂天数与对照组相比，差异无统计学差异(P>0.05)，但药物利用指数(DUI)>1的比例，对照组为77.80%，研究组为40.00%；中药注射剂费用占住院总费用比，对照组为24.49%，研究组为20.46%；中药注射剂的不合理使用比例，对照组为22.00%，研究组为14.00%。结论：临床药师的有效干预可以降低超剂量用药的比例，降低中药注射剂费用占比，同时提高其临床使用安全性。
关键词 中药注射剂 合理使用 干预 临床药师
中图分类号：R286 文献标识码：A 文章编号：1006-1533(2016)16-0011-04
Research of clinical pharmacists participating in the rational application of Chinese traditional medicine injection
GU Yan， SHEN Hui， QIAN Fang( Department of Pharmacy， Jiading Hospital of Traditional Chinese Medicine， Shanghai 201800， China)
ABSTRACT Objective： To evaluate the effect of clinical pharmacists in the intervention of rational use of traditional Chinese medicine (TCM) injections. Methods： By systematic sampling method， 100 inpatient prescriptions were extracted in the fourth quarter of 2013， and another 100 inpatient prescriptions were extracted in the fourth quarter of 2014， respectively， and they were divided into a research group and a control group. The use of traditional Chinese medicine injections was statistically analyzed in the two groups. Results： After the clinical pharmacist intervention， the days of use of traditional Chinese medicine injections in the inpatients had no significant difference between the research group and the control one(P>0.05)， but proportions of drug utilization index(DUI)>1 were 77.80% and 40.00% in the control group and the research one， respectively. The proportions that the cost of traditional Chinese medicine injection accounted for the total hospitalization cost were 24.49% and 20.46% in the control group and the research one. The proportion of irrational use of traditional Chinese medicine injections were 22.00% and 14.00% in the control group and the research one. Conclusion： Effective intervention of clinical pharmacists can reduce the proportions of drug overdose and traditional Chinese medicine injection costs and improve the clinical safety at the same time.
KEY WORDS traditional Chinese medicine injection； rational use； intervention； clinical pharmacist
中药注射剂在临床上被广泛应用于心脑血管疾病、危重病症和恶性肿瘤等治疗，疗效亦得到了广泛认可[1]。然而，由于中药注射剂存在原药质量不稳定、成分复杂、有效成分难以控制和质量标准不完善等因素，其安全性受到一定程度的影响[2]。近年来，中药注射剂导致的严重不良反应报道越来越多，除了上述原因外，临床的不合理使用也是造成中药注射剂不良反应的重要因素。
为了提高中药注射剂的合理使用，我中心临床药学组对中药注射剂的使用进行了管理和干预。本文将干预前后中药注射剂的使用情况进行了对比分析，探讨药学干预在促进中药注射剂合理使用中的意义。
1 资料与方法
1.1 资料来源 (顾艳 沈慧 钱芳)
关键词 中药注射剂 合理使用 干预 临床药师
中图分类号：R286 文献标识码：A 文章编号：1006-1533(2016)16-0011-04
Research of clinical pharmacists participating in the rational application of Chinese traditional medicine injection
GU Yan， SHEN Hui， QIAN Fang( Department of Pharmacy， Jiading Hospital of Traditional Chinese Medicine， Shanghai 201800， China)
ABSTRACT Objective： To evaluate the effect of clinical pharmacists in the intervention of rational use of traditional Chinese medicine (TCM) injections. Methods： By systematic sampling method， 100 inpatient prescriptions were extracted in the fourth quarter of 2013， and another 100 inpatient prescriptions were extracted in the fourth quarter of 2014， respectively， and they were divided into a research group and a control group. The use of traditional Chinese medicine injections was statistically analyzed in the two groups. Results： After the clinical pharmacist intervention， the days of use of traditional Chinese medicine injections in the inpatients had no significant difference between the research group and the control one(P>0.05)， but proportions of drug utilization index(DUI)>1 were 77.80% and 40.00% in the control group and the research one， respectively. The proportions that the cost of traditional Chinese medicine injection accounted for the total hospitalization cost were 24.49% and 20.46% in the control group and the research one. The proportion of irrational use of traditional Chinese medicine injections were 22.00% and 14.00% in the control group and the research one. Conclusion： Effective intervention of clinical pharmacists can reduce the proportions of drug overdose and traditional Chinese medicine injection costs and improve the clinical safety at the same time.
KEY WORDS traditional Chinese medicine injection； rational use； intervention； clinical pharmacist
中药注射剂在临床上被广泛应用于心脑血管疾病、危重病症和恶性肿瘤等治疗，疗效亦得到了广泛认可[1]。然而，由于中药注射剂存在原药质量不稳定、成分复杂、有效成分难以控制和质量标准不完善等因素，其安全性受到一定程度的影响[2]。近年来，中药注射剂导致的严重不良反应报道越来越多，除了上述原因外，临床的不合理使用也是造成中药注射剂不良反应的重要因素。
为了提高中药注射剂的合理使用，我中心临床药学组对中药注射剂的使用进行了管理和干预。本文将干预前后中药注射剂的使用情况进行了对比分析，探讨药学干预在促进中药注射剂合理使用中的意义。
1 资料与方法
1.1 资料来源 (顾艳 沈慧 钱芳)