个性化运动方案对2型糖尿病患者糖化血红蛋白的影响(1)
摘 要 目的：探讨个性化运动方案对2型糖尿病患者糖化血红蛋白的影响。方法：选择2014年4月—10月内分泌病房2型糖尿病患者70例。随机分为对照组35例，予以常规运动指导；干预组35例，予以个性化运动方案。两组患者出院后均每周进行运动记录和自我血糖监测，电话追踪并予阶段总结与指导。分别收集两组患者出院时及出院3个月后的糖化血红蛋白指标。结果：对照组出院时和出院后的糖化血红蛋白水平分别为(9.90±1.83)%和(8.85±1.79)%；干预组分别为(10.18±2.31)%和(7.01±0.80)%。两组出院后3个月的糖化血红蛋白随时间延长呈下降趋势，并且干预组明显低于对照组，经线性模型重复测量方差分析比较，不同测量时间及两组间的糖化血红蛋白值差异有统计学意义(P<0.01)，且两者间存在交互作用(P<0.01)。结论：运动指导是一项有效控制糖尿病的干预方法，个性化的运动方案较之常规运动指导对控制患者的糖化血红蛋白、降低血糖有着更好的效果。
关键词 糖尿病 个性化 干预 糖化血红蛋白
中图分类号：R587.1 文献标识码：A 文章编号：1006-1533(2016)18-0047-03
Influence of individualized exercise program on glycosylated hemoglobin in patients with type 2 diabetes
LIN Ling， ZHAO Chunyan， JIN Xin， FENG Jiayi， CHEN Wenting
(Department of Endocrinology， East Hospital affiliated to Tongji University， Shanghai 200120， China)
ABSTRACT Objective： To define the influence of the individualized exercise program on glycosylated hemoglobin of the patients with type 2 diabetes. Methods： From April to October 2014， 70 cases of type 2 diabetes in the hospital’s endocrine ward were selected， and randomly divided into a control group and an intervention group. The patients in the control group were given the regular exercise guidance， and the patients in the intervention group were given the individualized exercise programs. After being discharged， their exercises and self-monitoring of blood glucose were recorded weekly and followed up by telephone， which were summarized and guided in the different stages. After three months， the indexes of glycosylated hemoglobin were collected before and after being discharged from the hospital. Results： The levels of glycosylated hemoglobin in the control group were(9.90±1.83) % and(8.85±1.79) % and the levels of glycosylated hemoglobin in the intervention group were (10.18±2.31)% and(7.01±0.80) % at discharge and after discharge， respectively. Glycosylated hemoglobin showed a downward trend in the patients of the two groups after 3 months of being discharged， and the glycosylated hemoglobin of the intervention group was lower than that of the control group. Compared by the repeated measures analysis of variance in the linear model， the differences of glycosylated hemoglobin values between the two groups at the different measuring time had the statistical significance(P<0.01)， and there was interaction between them(P<0.01). Conclusion： Exercise guidance is an effective intervention method for glucose control in patients with diabetes. Compared with the conventional exercise guidance， the individualized exercise program has a better effect on controlling the glycosylated hemoglobin and lowering blood glucose of the patients. (林玲 赵春艳 金鑫 冯嘉依 陈雯婷)
关键词 糖尿病 个性化 干预 糖化血红蛋白
中图分类号：R587.1 文献标识码：A 文章编号：1006-1533(2016)18-0047-03
Influence of individualized exercise program on glycosylated hemoglobin in patients with type 2 diabetes
LIN Ling， ZHAO Chunyan， JIN Xin， FENG Jiayi， CHEN Wenting
(Department of Endocrinology， East Hospital affiliated to Tongji University， Shanghai 200120， China)
ABSTRACT Objective： To define the influence of the individualized exercise program on glycosylated hemoglobin of the patients with type 2 diabetes. Methods： From April to October 2014， 70 cases of type 2 diabetes in the hospital’s endocrine ward were selected， and randomly divided into a control group and an intervention group. The patients in the control group were given the regular exercise guidance， and the patients in the intervention group were given the individualized exercise programs. After being discharged， their exercises and self-monitoring of blood glucose were recorded weekly and followed up by telephone， which were summarized and guided in the different stages. After three months， the indexes of glycosylated hemoglobin were collected before and after being discharged from the hospital. Results： The levels of glycosylated hemoglobin in the control group were(9.90±1.83) % and(8.85±1.79) % and the levels of glycosylated hemoglobin in the intervention group were (10.18±2.31)% and(7.01±0.80) % at discharge and after discharge， respectively. Glycosylated hemoglobin showed a downward trend in the patients of the two groups after 3 months of being discharged， and the glycosylated hemoglobin of the intervention group was lower than that of the control group. Compared by the repeated measures analysis of variance in the linear model， the differences of glycosylated hemoglobin values between the two groups at the different measuring time had the statistical significance(P<0.01)， and there was interaction between them(P<0.01). Conclusion： Exercise guidance is an effective intervention method for glucose control in patients with diabetes. Compared with the conventional exercise guidance， the individualized exercise program has a better effect on controlling the glycosylated hemoglobin and lowering blood glucose of the patients. (林玲 赵春艳 金鑫 冯嘉依 陈雯婷)