杏苏二陈汤治疗慢性支气管炎急性发作期(风寒证)的临床观察(1)
摘 要 目的：分析杏苏二陈汤治疗慢性支气管炎急性发作期(风寒证)的临床效果。方法：选取2014年11月至2016年11月收治的慢性支气管炎急性发作期(风寒证)患者120例，分为对照组和观察组各60例。对照组采用口服止咳丸治疗，每次6粒，每日2次。观察组给予杏苏二陈汤治疗，每次200 ml，每日3次。两组均以1周为1个疗程，共治疗2个疗程。分析两组治疗有效率和症状体征积分改善情况。结果：对照组总有效率为86.7%(52/60)，明显低于观察组的98.3%(59/60，P<0.05)。观察组的症状体征积分改善明显好于对照组(P<0.05)。对照组不良反应为16.7%(10/60)，明显高于观察组的1.7%(1/60，P<0.05)。结论：苏杏二陈汤治疗慢性支气管炎急性发作期(风寒证)可以有效改善患者的症状，安全性高。
关键词 慢性支气管炎；风寒证；杏苏二陈汤
中图分类号：R562.2 文献标志码：A 文章编号：1006-1533(2017)12-0027-02
Clinical observation of xingsu erchen decoction in the treatment of acute exacerbation of chronic bronchitis (cold syndrome)
ZHOU Tong
(Linyun Community Health Service Center of Xiuhui District， Shanghai 200237， China)
ABSTRACT Objective： To analyze the clinical effect of xingsu erchen decoction in the treatment of acute exacerbation of chronic bronchitis. Methods： From November 2014 to November 2016 120 patients with acute exacerbation of chronic bronchitis (wind cold syndrome) in the hospital were selected and randomly divided into a control group and an observation group with 60 cases each. The control group was treated with oral cough pill， 6 pills each time， 2 times a day. The observation group was given xingsu erchen decoction treatment， 200 ml each time， 3 times a day. The two groups were treated for 1 course 1 week， and a total of 2 courses. The effective rates of treatment and improvement of symptom and sign scores of the two groups were analyzed. Results： The total effective rate in the control group was 86.7%(52/60)， which was significantly lower than that in the observation group 98.3%(59/60， P<0.05). The improvement of symptom and sign scores in the observation group was significantly better than that in the control group(P<0.05). The adverse reaction in the control group was 16.7%(10/60)， which was significantly higher than that in the observation group 1.7%(1/60， P<0.05). Conclusion： Xingsu erchen decoction in the treatment of acute exacerbation of chronic bronchitis (cold syndrome) can effectively improve the symptoms of patients， and has high safety.
KEY WORDS acute exacerbation of chronic bronchitis； wind cold syndrome； xingsu erchen decoction
慢性支氣管炎急性发作期临床表现为痰量增多、粘稠度增加、偶尔痰中带血或出现黄色脓性痰[1]，如果没有积极治疗，随着病情的加重，患者会出现咳嗽及咳痰、气急不能平卧现象，严重影响患者身心健康[2]。风寒证的临床症状为咳嗽声重、痰多、发热、鼻塞、舌淡或夹青、苔薄或白腻、脉浮紧或滑[3]。本文报道杏苏二陈汤治疗慢性支气管炎急性发作期(风寒证)的临床效果。
1 资料与方法
1.1 一般资料
选取2014年11月至2016年11月凌云街道社区卫生服务中心收治的慢性支气管炎急性发作期(风寒证)患者120例，临床检查和临床症状均符合《中医内科学》和《中药新药临床研究指导原则》[4]，年龄50～65岁，平均(57.5±9.8)岁，分为对照组和观察组各60例。患者均签订知情同意书。排除标准：①因矽肺、肿瘤、真菌等因素引起的慢性咳嗽喘息患者；②过敏体质患者；③患有严重心脑肺等系统原发性疾病患者。 (周彤)
关键词 慢性支气管炎；风寒证；杏苏二陈汤
中图分类号：R562.2 文献标志码：A 文章编号：1006-1533(2017)12-0027-02
Clinical observation of xingsu erchen decoction in the treatment of acute exacerbation of chronic bronchitis (cold syndrome)
ZHOU Tong
(Linyun Community Health Service Center of Xiuhui District， Shanghai 200237， China)
ABSTRACT Objective： To analyze the clinical effect of xingsu erchen decoction in the treatment of acute exacerbation of chronic bronchitis. Methods： From November 2014 to November 2016 120 patients with acute exacerbation of chronic bronchitis (wind cold syndrome) in the hospital were selected and randomly divided into a control group and an observation group with 60 cases each. The control group was treated with oral cough pill， 6 pills each time， 2 times a day. The observation group was given xingsu erchen decoction treatment， 200 ml each time， 3 times a day. The two groups were treated for 1 course 1 week， and a total of 2 courses. The effective rates of treatment and improvement of symptom and sign scores of the two groups were analyzed. Results： The total effective rate in the control group was 86.7%(52/60)， which was significantly lower than that in the observation group 98.3%(59/60， P<0.05). The improvement of symptom and sign scores in the observation group was significantly better than that in the control group(P<0.05). The adverse reaction in the control group was 16.7%(10/60)， which was significantly higher than that in the observation group 1.7%(1/60， P<0.05). Conclusion： Xingsu erchen decoction in the treatment of acute exacerbation of chronic bronchitis (cold syndrome) can effectively improve the symptoms of patients， and has high safety.
KEY WORDS acute exacerbation of chronic bronchitis； wind cold syndrome； xingsu erchen decoction
慢性支氣管炎急性发作期临床表现为痰量增多、粘稠度增加、偶尔痰中带血或出现黄色脓性痰[1]，如果没有积极治疗，随着病情的加重，患者会出现咳嗽及咳痰、气急不能平卧现象，严重影响患者身心健康[2]。风寒证的临床症状为咳嗽声重、痰多、发热、鼻塞、舌淡或夹青、苔薄或白腻、脉浮紧或滑[3]。本文报道杏苏二陈汤治疗慢性支气管炎急性发作期(风寒证)的临床效果。
1 资料与方法
1.1 一般资料
选取2014年11月至2016年11月凌云街道社区卫生服务中心收治的慢性支气管炎急性发作期(风寒证)患者120例，临床检查和临床症状均符合《中医内科学》和《中药新药临床研究指导原则》[4]，年龄50～65岁，平均(57.5±9.8)岁，分为对照组和观察组各60例。患者均签订知情同意书。排除标准：①因矽肺、肿瘤、真菌等因素引起的慢性咳嗽喘息患者；②过敏体质患者；③患有严重心脑肺等系统原发性疾病患者。 (周彤)