肿瘤干细胞研究进展(1)
摘 要 近年来肿瘤干细胞正逐渐成为研究焦点。越来越多的证据表明肿瘤干细胞与肿瘤的形成、进展、转移、复发与治疗失败存在密切联系。本文主要就肿瘤干细胞假说的起源、上皮间充质转换、CD44与肿瘤干细胞的联系、肿瘤干细胞抵抗治疗的可能机制、肿瘤干细胞的信号通路及其治疗启示等五个方面展开论述。
关键词 肿瘤干细胞 上皮间充质转换 CD44 信号通路 肿瘤治疗
中图分类号:R730.231 文献标识码:A 文章编号:1006-1533(2017)15-0028-04
Research progress of cancer stem cells*
YU Mincheng**, XU Yang***
(Department of Liver Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China)
ABSTRACT Cancer stem cells (CSCs) have been the subject of intensive discussion and investigation for decades. Accumulated evidence indicates that CSCs play a crucial role in tumor initiation ......
您现在查看是摘要页,全文长 3886 字符。
关键词 肿瘤干细胞 上皮间充质转换 CD44 信号通路 肿瘤治疗
中图分类号:R730.231 文献标识码:A 文章编号:1006-1533(2017)15-0028-04
Research progress of cancer stem cells*
YU Mincheng**, XU Yang***
(Department of Liver Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China)
ABSTRACT Cancer stem cells (CSCs) have been the subject of intensive discussion and investigation for decades. Accumulated evidence indicates that CSCs play a crucial role in tumor initiation ......
您现在查看是摘要页,全文长 3886 字符。