馥感啉口服液治疗儿童胃肠型感冒临床观察(1)
摘 要 目的：观察馥感啉口服液治疗儿童胃肠型感冒的临床疗效。方法：将112例胃肠型感冒患儿按随机数字表法分为观察组和对照组各56例，对照组采用西医常规治疗，观察组采用馥感啉口服液治疗，3 d为一个疗程，治疗1～2个疗程。观察两组患儿治疗前后症状变化及不良反应情况，比较两组症状积分，并评价临床疗效及安全性。结果：治疗后两组症状积分均较治疗前下降，治疗后观察组症状积分低于对照组，观察组疗效优于对照组(92.86% vs 69.64%)，差异均有统计学意义(P<0.05)；随访中，观察组未出现明显药物不良反应，对照组患儿出现便秘、皮疹各1例，停药后症状消失。结论：馥感啉口服液扶正祛邪、标本兼顾，治疗儿童胃肠型感冒疗效显著。
关键词 馥感啉口服液 胃肠型感冒 儿童
中图分类号：R286； R272.5 文献标识码：A 文章编号：1006-1533(2018)03-0033-04
Clinical observation of Fuganlin oral liquid for the treatment of gastrointestinal cold of children
DAI Wei1*， WAN Lipeng1， WANG Shaojie2**(1. Graduate School， Dalian Medical University， Dalian 116044， China； 2. Department of Chinese Medicine，Dalian Children’s Hospital affiliated to Dalian Medical University， Dalian 116012， China)
ABSTRACT Objective： To observe the clinical efficacy of Fuganlin oral liquid in the treatment of children’s gastrointestinal cold. Methods： Total 112 children patients with gastrointestinal cold were randomly divided into an observation group and a control group with 56 cases each. The control group was given routine treatment of western medicine while the observation group with Fuganlin oral liquid. A course of treatment was 3 day and both groups were treated for 1 to 2 courses. The changes of symptoms and adverse reactions in both groups were observed before and after treatment to compare symptom scores and to evaluate clinical efficacy and safety. Result： Symptom scores of both groups were decreased after treatment than before(P<0.05)， and the symptom scores were lower in the observation group than in the control group after treatment (P<0.05). The total clinical effective rate was better in the observation group than in the control group (92.86% vs 69.64%) (P<0.05). Adverse drug reactions were not found in the observation group but 1 case of constipation and 1 case of erythra in the control group during follow-up， which disappeared after withdrawal. Conclusion： Fuganlin oral liquid can strengthen the body resistance and eliminate pathogenic factors， and give consideration to both external symptoms and causative reasons. It is effective in the treatment of children’s gastrointestinal cold.
KEY WORDS Fuganlin oral liquid； gastrointestinal cold； children
胃腸型感冒，是流行性感冒临床表现的一种类型[1]，一般急性起病，由病毒感染引起，可合并细菌感染[2-3]。本病类似于中医的感冒夹滞，除发热、鼻塞、流涕、喷嚏、咳嗽、头身疼痛等感冒症状外，还伴有腹痛、腹泻、呕吐、食欲不振等消化道表现 [4]。小儿脏腑娇嫩，形气未充，外邪侵袭，直中脾胃，极易发为本病，临床上十分常见。西医常规治疗以对症支持、抗病毒及抗生素为主。然而，抗生素对病毒感染无效，还容易刺激患儿胃肠道和导致肠道菌群失调，进一步加重腹痛、腹泻等症状；抗病毒西药则疗效多不确切，且可见皮疹、瘙痒、肝功能异常、贫血、粒细胞数量下降等多种不良反应[5]，儿童尤当谨用。故西医治疗本病，尚缺乏有效的药物。本研究以馥感啉口服液治疗儿童胃肠型感冒，扶正祛邪，取得良好疗效。, 百拇医药(代薇 万里鹏 王绍洁)
关键词 馥感啉口服液 胃肠型感冒 儿童
中图分类号：R286； R272.5 文献标识码：A 文章编号：1006-1533(2018)03-0033-04
Clinical observation of Fuganlin oral liquid for the treatment of gastrointestinal cold of children
DAI Wei1*， WAN Lipeng1， WANG Shaojie2**(1. Graduate School， Dalian Medical University， Dalian 116044， China； 2. Department of Chinese Medicine，Dalian Children’s Hospital affiliated to Dalian Medical University， Dalian 116012， China)
ABSTRACT Objective： To observe the clinical efficacy of Fuganlin oral liquid in the treatment of children’s gastrointestinal cold. Methods： Total 112 children patients with gastrointestinal cold were randomly divided into an observation group and a control group with 56 cases each. The control group was given routine treatment of western medicine while the observation group with Fuganlin oral liquid. A course of treatment was 3 day and both groups were treated for 1 to 2 courses. The changes of symptoms and adverse reactions in both groups were observed before and after treatment to compare symptom scores and to evaluate clinical efficacy and safety. Result： Symptom scores of both groups were decreased after treatment than before(P<0.05)， and the symptom scores were lower in the observation group than in the control group after treatment (P<0.05). The total clinical effective rate was better in the observation group than in the control group (92.86% vs 69.64%) (P<0.05). Adverse drug reactions were not found in the observation group but 1 case of constipation and 1 case of erythra in the control group during follow-up， which disappeared after withdrawal. Conclusion： Fuganlin oral liquid can strengthen the body resistance and eliminate pathogenic factors， and give consideration to both external symptoms and causative reasons. It is effective in the treatment of children’s gastrointestinal cold.
KEY WORDS Fuganlin oral liquid； gastrointestinal cold； children
胃腸型感冒，是流行性感冒临床表现的一种类型[1]，一般急性起病，由病毒感染引起，可合并细菌感染[2-3]。本病类似于中医的感冒夹滞，除发热、鼻塞、流涕、喷嚏、咳嗽、头身疼痛等感冒症状外，还伴有腹痛、腹泻、呕吐、食欲不振等消化道表现 [4]。小儿脏腑娇嫩，形气未充，外邪侵袭，直中脾胃，极易发为本病，临床上十分常见。西医常规治疗以对症支持、抗病毒及抗生素为主。然而，抗生素对病毒感染无效，还容易刺激患儿胃肠道和导致肠道菌群失调，进一步加重腹痛、腹泻等症状；抗病毒西药则疗效多不确切，且可见皮疹、瘙痒、肝功能异常、贫血、粒细胞数量下降等多种不良反应[5]，儿童尤当谨用。故西医治疗本病，尚缺乏有效的药物。本研究以馥感啉口服液治疗儿童胃肠型感冒，扶正祛邪，取得良好疗效。, 百拇医药(代薇 万里鹏 王绍洁)