天麻钩藤饮联合氨氯地平治疗老年高血压的疗效观察(1)
摘 要 目的：观察天麻钩藤饮联合氨氯地平治疗老年高血压的临床疗效。方法：选取86例老年高血压患者作为研究对象，将其随机分成对照组和研究组各43例，对照组给予氨氯地平治疗，研究组给予天麻钩藤饮联合氨氯地平治疗，比较两组治疗前后的血压水平、治疗总有效率及不良反应发生率。结果：治疗前，两组的收缩压(SBP)、舒张压(DBP)比较无显著性差异(P>0.05)；治疗后，研究组SBP、DBP水平及不良反应发生率明显低于对照组，治疗的总有效率明显高于对照组，两组比较有显著性差异(P<0.05)。结论：采用天麻钩藤饮联合氨氯地平对老年高血压患者进行治疗，具有降压效果显著、不良反应小等优势，是一种安全、高效的组合治疗方案。
关键词 天麻钩藤饮 氨氯地平 老年高血压
中图分类号：R289.5； R544.1 文献标志码：B 文章编号：1006-1533(2018)23-0060-03
Therapeutic effect of Tianma Gouteng decoction combined with amlodipine on the elderly with hypertension
ZHAO Guoyi， GUAN Zongyao， LIANG Hui
(Yunfu Traditional Chinese Medicine Hospital， Guangdong Yunfu 527300， China)
ABSTRACT Objective： To observe the clinical efficacy of Tianma Gouteng decoction combined with amlodipine in the treatment of the elderly with hypertension. Methods： Eighty-six elderly patients with hypertension were selected as the study subjects and they were randomly divided into a control group and a study group with 43 cases each. The control group was treated with amlodipine while the study group with Tianma Gouteng decoction combined with amlodipine. Blood pressure levels before and after treatment， total effective rate and incidence of adverse reactions were compared between the two groups. Results： There were no significant differences in systolic blood pressure (SBP) and diastolic blood pressure (DBP) between the two groups before treatment (P>0.05). SBP and DBP levels and the incidence of adverse reactions were significantly lower and the total effective rate was significantly higher in the study group than the control group after treatment (P<0.05). Conclusion： Tianma Gouteng decoction combined with amlodipine for the treatment of elderly patients with hypertension has the advantages of significant antihypertensive effect and less adverse reactions and is a safe and effective combination therapy.
KEY WORDS Tianma Gouteng decoction； amlodipine； elderly hypertension
高血壓是老年人群多发疾病，也是临床最常见的心血管疾病之一，数据显示，中国目前至少有2亿人口患有高血压[1]。该疾病主要临床表现为动脉血压升高，随着血压的持续升高，还会损害患者的心脑、肾脏和血管等重要器官，从而对患者的身心健康和生命安全造成严重威胁[2]。为控制和降低患者的血压水平，西医临床多采用血管紧张素转换酶抑制剂、钙拮抗剂等药物对老年高血压进行治疗，虽具有一定的功效，但长期应用这些药物，易使患者产生药物依赖性和出现较多的不良反应。随着中医治疗技术的不断发展，不少临床采用中西医结合方式对老年高血压患者进行治疗，获得满意的疗效[3]，笔者观察了天麻钩藤饮联合氨氯地平治疗老年高血压的临床疗效。
1 资料与方法
1.1 一般资料
选取广东省云浮市中医院2016年5月—2017年5月收治的86例老年高血压患者作为研究对象，采用随机分组法将患者分成对照组和研究组，每组43例。对照组中男性26例，女性17例；年龄61.5～76.4岁，平均年龄(70.2±2.1)岁；病程4.3～10.5年，平均病程 (7.1±1.2)年。研究组中男性24例，女性19例；年龄60.8～75.2岁，平均年龄(69.8±2.3)岁；病程4.0～10.7年，平均病程(7.0±1.3)年。两组患者的年龄、病程等一般资料比较无显著差异，具有可比性(P>0.05)。, http://www.100md.com(招国仪 关宗耀 梁辉)
关键词 天麻钩藤饮 氨氯地平 老年高血压
中图分类号：R289.5； R544.1 文献标志码：B 文章编号：1006-1533(2018)23-0060-03
Therapeutic effect of Tianma Gouteng decoction combined with amlodipine on the elderly with hypertension
ZHAO Guoyi， GUAN Zongyao， LIANG Hui
(Yunfu Traditional Chinese Medicine Hospital， Guangdong Yunfu 527300， China)
ABSTRACT Objective： To observe the clinical efficacy of Tianma Gouteng decoction combined with amlodipine in the treatment of the elderly with hypertension. Methods： Eighty-six elderly patients with hypertension were selected as the study subjects and they were randomly divided into a control group and a study group with 43 cases each. The control group was treated with amlodipine while the study group with Tianma Gouteng decoction combined with amlodipine. Blood pressure levels before and after treatment， total effective rate and incidence of adverse reactions were compared between the two groups. Results： There were no significant differences in systolic blood pressure (SBP) and diastolic blood pressure (DBP) between the two groups before treatment (P>0.05). SBP and DBP levels and the incidence of adverse reactions were significantly lower and the total effective rate was significantly higher in the study group than the control group after treatment (P<0.05). Conclusion： Tianma Gouteng decoction combined with amlodipine for the treatment of elderly patients with hypertension has the advantages of significant antihypertensive effect and less adverse reactions and is a safe and effective combination therapy.
KEY WORDS Tianma Gouteng decoction； amlodipine； elderly hypertension
高血壓是老年人群多发疾病，也是临床最常见的心血管疾病之一，数据显示，中国目前至少有2亿人口患有高血压[1]。该疾病主要临床表现为动脉血压升高，随着血压的持续升高，还会损害患者的心脑、肾脏和血管等重要器官，从而对患者的身心健康和生命安全造成严重威胁[2]。为控制和降低患者的血压水平，西医临床多采用血管紧张素转换酶抑制剂、钙拮抗剂等药物对老年高血压进行治疗，虽具有一定的功效，但长期应用这些药物，易使患者产生药物依赖性和出现较多的不良反应。随着中医治疗技术的不断发展，不少临床采用中西医结合方式对老年高血压患者进行治疗，获得满意的疗效[3]，笔者观察了天麻钩藤饮联合氨氯地平治疗老年高血压的临床疗效。
1 资料与方法
1.1 一般资料
选取广东省云浮市中医院2016年5月—2017年5月收治的86例老年高血压患者作为研究对象，采用随机分组法将患者分成对照组和研究组，每组43例。对照组中男性26例，女性17例；年龄61.5～76.4岁，平均年龄(70.2±2.1)岁；病程4.3～10.5年，平均病程 (7.1±1.2)年。研究组中男性24例，女性19例；年龄60.8～75.2岁，平均年龄(69.8±2.3)岁；病程4.0～10.7年，平均病程(7.0±1.3)年。两组患者的年龄、病程等一般资料比较无显著差异，具有可比性(P>0.05)。, http://www.100md.com(招国仪 关宗耀 梁辉)