伤速康贴膏联合玻璃酸钠关节腔内注射治疗气滞血瘀证膝骨关节炎(1)
摘 要 目的：探讨外敷伤速康贴膏联合玻璃酸钠关节腔内注射治疗气滞血瘀证膝骨关节炎的临床疗效。方法：选取68例膝骨关节炎患者随机分为对照组和观察组各34例，对照组采用玻璃酸钠膝关节腔内注射治疗，观察组采用伤速康贴膏联合关节腔内注射玻璃酸钠治疗，4周后对患者膝关节疼痛、运动功能等指标进行评价，评估疗效。结果：观察组有效率高于对照组；VAS评分、关节休息痛、关节运动痛、肿胀、行走能力及总分优于对照组(P<0.05)。结论：伤速康贴膏联合关节腔内注射玻璃酸钠治疗气滞血瘀型膝骨关节炎具有较好的临床疗效。
关键词 膝骨关节炎 伤速康贴膏 玻璃酸钠
中图分类号：R274.9； R289.6 文献标志码：B 文章编号：1006-1533(2020)05-0043-04
Clinical observation of the treatment of knee osteoarthritis with qi stagnation and blood stasis syndrome by intra-articular injection of sodium hyaluronate
WEI Tengfei1*， ZHANG Bo2**， WANG Shuaibo1， WAN Yunfeng1， WEN Meng1(1. Hu’nan University of Traditional Chinese Medicine， Changsha 410208， China； 2. the First Hospital affiliated to Hu’nan University of Traditional Chinese Medicine， Changsha 410007， China)
ABSTRACT Objective： To investigate the clinical effect of external application of Shangsukang paste combined with intra-articular injection of sodium hyaluronate in the treatment of knee osteoarthritis with qi stagnation and blood stasis syndrome. Methods： Sixty-eight patients with knee osteoarthritis were randomly divided into a control group and an observation group with 34 cases each. The control group were treated with sodium hyaluronate injection alone while the observation group with Shangsukang plaster combined with sodium hyaluronate injection in the joint cavity. Knee pain， motor function and other indicators were evaluated by VAS pain score and knee lequesne-mery score 4 weeks after treatment. Results： The total effective rate of the was higher in the observation group than the control group (94.12% vs 82.35%， P<0.05). VAS scores， joint rest pain， joint motion pain， swelling， walking ability were better in the observation group than the control group (P<0.05). Conclusion： Clinical application of Shangsukang plaster combined with intra-articular injection of sodium hyaluronate for the treatment of knee osteoarthritis with qi stagnation and blood stasis has a significant effect.
KEY WORDS knee osteoarthritis； Shangsukang paster； sodium hyaluronate
膝骨關节炎(knee osteoarthritis KOA)是临床上中老年人群的常见疾病，发病机制较复杂，好发于50岁以上的较肥胖的中老年人，女性发病率高于男性[1]。临床主要表现为膝关节疼痛，可伴有肿胀、僵硬、畸形，疼痛时间逐渐延长，膝关节难以负重，患者下肢行走受限，造成慢性残障，生活质量受到极大影响，给家庭和社会带来沉重的经济负担[2]。本病治疗上目前主要有口服止痛药物、中药口服外用、关节腔注射药物及手术等方式，然而不良反应多，手术风险高，且单一治疗效果不佳。结合临床实际，应用伤速康贴膏联合玻璃酸钠关节腔内注射治疗，发挥中西医联合治疗的优势，能更好地缓解患者的痛苦。
1 资料和方法
1.1 一般资料
选取2018年4月—2019年4月就诊于湖南中医药大学第一附属医院骨伤科门诊的KOA患者68例，按随机数字表法分为观察组和对照组各34例。两组在性别、患侧、年龄、病程、X线分级等一般资料上比较，差异无统计学意义(P>0.05，表1)，具可比性。, 百拇医药(魏腾飞 张波 王帅博 万云峰 文猛)
关键词 膝骨关节炎 伤速康贴膏 玻璃酸钠
中图分类号：R274.9； R289.6 文献标志码：B 文章编号：1006-1533(2020)05-0043-04
Clinical observation of the treatment of knee osteoarthritis with qi stagnation and blood stasis syndrome by intra-articular injection of sodium hyaluronate
WEI Tengfei1*， ZHANG Bo2**， WANG Shuaibo1， WAN Yunfeng1， WEN Meng1(1. Hu’nan University of Traditional Chinese Medicine， Changsha 410208， China； 2. the First Hospital affiliated to Hu’nan University of Traditional Chinese Medicine， Changsha 410007， China)
ABSTRACT Objective： To investigate the clinical effect of external application of Shangsukang paste combined with intra-articular injection of sodium hyaluronate in the treatment of knee osteoarthritis with qi stagnation and blood stasis syndrome. Methods： Sixty-eight patients with knee osteoarthritis were randomly divided into a control group and an observation group with 34 cases each. The control group were treated with sodium hyaluronate injection alone while the observation group with Shangsukang plaster combined with sodium hyaluronate injection in the joint cavity. Knee pain， motor function and other indicators were evaluated by VAS pain score and knee lequesne-mery score 4 weeks after treatment. Results： The total effective rate of the was higher in the observation group than the control group (94.12% vs 82.35%， P<0.05). VAS scores， joint rest pain， joint motion pain， swelling， walking ability were better in the observation group than the control group (P<0.05). Conclusion： Clinical application of Shangsukang plaster combined with intra-articular injection of sodium hyaluronate for the treatment of knee osteoarthritis with qi stagnation and blood stasis has a significant effect.
KEY WORDS knee osteoarthritis； Shangsukang paster； sodium hyaluronate
膝骨關节炎(knee osteoarthritis KOA)是临床上中老年人群的常见疾病，发病机制较复杂，好发于50岁以上的较肥胖的中老年人，女性发病率高于男性[1]。临床主要表现为膝关节疼痛，可伴有肿胀、僵硬、畸形，疼痛时间逐渐延长，膝关节难以负重，患者下肢行走受限，造成慢性残障，生活质量受到极大影响，给家庭和社会带来沉重的经济负担[2]。本病治疗上目前主要有口服止痛药物、中药口服外用、关节腔注射药物及手术等方式，然而不良反应多，手术风险高，且单一治疗效果不佳。结合临床实际，应用伤速康贴膏联合玻璃酸钠关节腔内注射治疗，发挥中西医联合治疗的优势，能更好地缓解患者的痛苦。
1 资料和方法
1.1 一般资料
选取2018年4月—2019年4月就诊于湖南中医药大学第一附属医院骨伤科门诊的KOA患者68例，按随机数字表法分为观察组和对照组各34例。两组在性别、患侧、年龄、病程、X线分级等一般资料上比较，差异无统计学意义(P>0.05，表1)，具可比性。, 百拇医药(魏腾飞 张波 王帅博 万云峰 文猛)
参见：首页 > 医疗版 > 疾病专题 > 骨科 > 慢性非化脓性关节炎或关节病 > 骨关节炎