林敏 戴峥嵘 余小云

    摘 要 目的：探讨咪达唑仑联合瑞芬太尼治疗颅脑外伤术后躁动的疗效。方法：选取80例颅脑外伤术后躁动患者为研究对象，按照随机数表法分为研究组和对照组各40例。对照组给予丙泊酚联合瑞芬太尼治疗，研究组给予咪达唑仑联合瑞芬太尼治疗。比较两组患者的生命体征(呼吸、心率、平均动脉压、血氧饱和度)、疼痛度[非语言成人疼痛(NVPS)评分]、镇静程度(Ramsay)评分。结果：研究组呼吸、心率、平均动脉压、NVPS评分低于对照组，血氧饱和度水平、Ramsay评分高于对照组(P<0.05)。结论：咪达唑仑联合瑞芬太尼能更为显著缓解颅脑外伤术后躁动患者的疼痛度，提高镇静效果，稳定生命体征。

    关键词 丙泊酚 咪达唑仑 瑞芬太尼 颅脑外伤 术后躁动 疼痛 镇静

    中图分类号：R971.3； R651.15 文献标志码：B 文章编号：1006-1533(2021)23-0052-03

    Effect of midazolam combined with remifentanil in the treatment of agitation after craniocerebral trauma

    LIN Min1， DAI Zhengrong2， YU Xiaoyun1(1. Department of Critical Care Medicine， the Second People’ s Hospital of Jingdezhen City， Jingdezhen 333000， China； 2. Department of Pediatrics， the Third People’ s Hospital of Jingdezhen City， Jingdezhen 333000， China)

    ABSTRACT Objective： To explore the efficacy of midazolam combined with remifentanil in the treatment of agitation after craniocerebral trauma. Methods： Eighty patients with agitation after craniocerebral trauma were selected as the research subjects and divided into a study group and a control group with 40 cases each based on a random number table method. The control group was treated with propofol combined with remifentanil ......