107例非糜烂性胃食管反流病24hpH阻抗监测特点分析
李波静 田涛 石益海 张志玲 张洁卜勤煜 聂志红摘 要 目的:分析非糜烂性胃食管反流病(non-erosive reflux disease,NERD)24 h pH阻抗监测(multiple channel intraluminal pH-impedance reflux monitoring,MII-pH)特点。方法:收集首次行MII-pH监测的成年NERD(胃镜检查已排除其他食管器质性疾病)患者107例,分析24 h pH阻抗监测的pH通道和阻抗通道的各主要反流指标的阳性率。结果:pH通道的阳性率为27.6%,其中DeMeester积分的阳性率为27.1%,酸反流时间百分比的阳性率为12.8%。阻抗通道监测的阳性率为55.6%,其中反流总次数的阳性率为12.1%,液体酸反流和非酸反流次数相比差异有统计学意义(P<0.001),液体酸反流和气体反流次数相比差异有统计学意义(P<0.001);食团暴露时间百分比的阳性率为46.6%;症状相关性的阳性率为48.6%。MII-pH监测的总阳性率为61.7%。结论:MII-pH监测通过pH通道和阻抗通道可显著提高NERD的检出率,可为临床诊断和治疗提供一定的依据。
关键词 胃食管反流病;非糜烂性反流病;食管pH阻抗监测
中图分类号:R571 文献标志码:A 文章编号:1006-1533(2021)24-0028-05
Analysis of the characteristics of 24-hour pH impedance monitoring in 107 cases of non-erosive gastroesophageal reflux disease
LI Bojing1, TIAN Tao1, SHI Yihai1, ZHANG Zhiling2, ZHANG Jie2, BO Qinyu2, NIE Zhihong3(1.Department of Gastroenterology, 2.Endoscopic Center, 3. General Practice Department of Gongli Hospital, Pudong New District, Shanghai 200135, China)
ABSTRACT Objective: To analyze the characteristics of non-erosive reflux disease(NERD) 24 h pH impedance monitoring. Methods: One hundred and seven adult NERD patients who underwent 24 h pH impedance monitoring for the first time(other esophageal organic diseases had been excluded from gastroscopy) were collected ......
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