不同剂量地佐辛在重症监护机械通气患者中的应用效果对比
朱利柯 叶培军摘 要 目的:探讨不同剂量地佐辛在重症监护室(ICU)机械通气患者中的应用效果。方法:选择120例ICU机械通气患者,随机分为A、B、C组,各40例。A、B、C组常规治疗后分别给予1.0、2.0、3.0 mg/h地佐辛。观测三组给药前后生命体征、镇痛及镇静评分及不良反应情况。结果:B、C组给药1 d、2 d镇痛评分低于A组,B组给药8 h、1 d及2 d镇静评分均低于A、C组,C组给药8 h后呼吸频率低于A、B组,ICU及机械通气时间高于A、B组,A组联合用药比例高于B、C组(P<0.05);三组均无明显不良反应。结论:ICU机械通气患者使用地佐辛2.0 mg/h具有良好镇痛镇静效果,可缩短入住ICU时间。
关键词 重症监护 机械通气 地佐辛 剂量
中图分类号:R971.2 文献标志码:A 文章编号:1006-1533(2022)01-0015-04
Comparison of the effect of different doses of dezocine in patients with mechanical ventilation in intensive care unit
ZHU Like, YE Peijun
[Department of Critical Care Medicine, Tumor Hospital affiliated to Zhengzhou University(He’nan Tumor Hospital), Zhengzhou 450000, China]
ABSTRACT Objective: To explore the effect of different doses of dezocine in mechanically ventilated patients at the intensive care unit. Methods: A total of 120 mechanically ventilated ICU patients were selected and randomly divided into groups A, B, and C with 40 cases each. Groups A, B, and C were given 1.0, 2.0, 3.0 mg/h dezocine after conventional treatment ......
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