胺碘酮联合阿托伐他汀治疗冠心病伴心律失常的疗效研究
郑华 胡亚兰 张绵 曾东摘 要 目的:观察胺碘酮联合阿托伐他汀治疗冠心病(CHD)伴心律失常的疗效。方法:将78例CHD伴心律失常患者随机分为对照组(n=36)和观察组(n=42),两组均接受CHD基础治疗和口服阿托伐他汀,对照组另给予盐酸普罗帕酮片治疗,观察组另给予盐酸胺碘酮片治疗。观察治疗前后两组患者24 h动态心电图相关指标、心功能指标、血液黏度指标,检测血清hs-CRP、Hcy、BNP水平变化;评价两组疗效及不良反应情况。结果:治疗后观察组心电图、心功能、血液黏度指标、hs-CRP、Hcy、BNP、治疗总有效率均优于对照组(均P<0.05);两组不良反应发生率差异无统计学意义(P>0.05)。结论:胺碘酮联合阿托伐他汀治疗CHD伴心律失常可有效改善心功能,降低血液黏度和血清hs-CRP、Hcy、BNP水平。
关键词 冠心病 心律失常 胺碘酮 阿托伐他汀 疗效
中图分类号:R972.2; R541.7 文献标志码:B 文章编号:1006-1533(2022)09-0014-04
引用本文 郑华, 胡亚兰, 张绵, 等. 胺碘酮联合阿托伐他汀治疗冠心病伴心律失常的疗效研究[J]. 上海医药, 2022, 43(9): 14-17; 22.
Efficacy of amiodarone combined with atorvastatin in the treatment of coronary heart disease with arrhythmia
ZHENG Hua, HU Yalan, ZHANG Mian, ZENG Dong
(Department of Critical Care Medicine, the Seventh People’s Hospital of Zhengzhou, Zhengzhou 450016, China)
ABSTRACT Objective: To observe the efficacy of amiodarone combined with atorvastatin in the treatment of coronary heart disease (CHD) with arrhythmia. Methods: Seventy-eight patients with CHD and arrhythmia were randomly divided into a control group (n=36) and an observation group (n=42). Both groups received basic CHD treatment and oral atorvastatin ......
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