QRS时限与心力衰竭患者利钠肽及心脏超声参数的相关性研究
苏朝霞 龚辉摘 要 目的:研究心電图QRS时限(QRSd)与心力衰竭(心衰)患者心功能部分评价指标的相关性。方法:收集2018年6月-2020年2月复旦大学附属金山医院心血管内科收治的住院心衰患者324例的临床资料,根据QRSd分为四组:QRSd<110 ms组、110 ms≤QRSd<130 ms组、130 ms≤QRSd<150 ms组和QRSd≥150 ms组,比较四组间心功能评价指标利钠肽(BNP)、心脏超声参数的差异。结果:年龄在四组间有明显差异,且变化与QRSd较弱呈正相关(r=0.142,P=0.005),BNP与QRSd呈正相关(r=0.167,P=0.001)。心衰患者中左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD)、左房内径(LAD)与QRSd呈正相关(r=0.403,P<0.001;r=0.413,P<0.001;r=0.154,P=0.003)。多重线性回归显示LVEDD对QRSd的影响最大(β=0.273),其次为LVESD(β=0.18),左室射血分数(LVEF)、左心室短轴缩短率(FS)与QRSd呈负相关(r=-0.499,P<0.001;r=-0.328,P=0.018)。结论:心衰患者随着QRSd延长,心功能越差。
关键词 心力衰竭;QRS时限;利钠肽;心脏超声
中图分类号:R541.6 文献标志码:A 文章编号:1006-1533(2023)08-0031-05
引用本文 苏朝霞, 龚辉. QRS时限与心力衰竭患者利钠肽及心脏超声参数的相关性研究[J]. 上海医药, 2023, 44(8): 31-35.
Study of correlation of QRS duration with natriuretic peptide and cardiac ultrasound parameters in patients with heart failure
SU Zhaoxia, GONG Hui
(Department of Cardiovasology of Jinshan Hospital affiliated to Fudan University, Shanghai 201508, China)
ABSTRACT Objective: To study correlation between QRS duration of electrocardiogram(QRSd) and partial evaluation indexes of cardiac function in patients with heart failure(HF). Methods: Clinical data of 324 hospitalized patients with heart failure from June 2018 to February 2020 in the Department of Cardiology of Jinshan Hospital affiliated to Fudan University were collected ......
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