摘要：目的探讨可逆性后部白质脑病综合征(RPLS)的病因、临床表现及影像学特征。方法分析20例RPLS患者的临床及影像学资料，总结该病的病因、临床表现及头颅MRI影像改变。结果高血压与子痫是最主要的病因，主要临床表现为头痛，痫性发作，视觉障碍，恶心、呕吐，意识状态改变，精神异常和行为改变。MRI表现：病变主要累及顶枕叶皮层，可波及额颞叶，可累及脑干、小脑、丘脑。T1WI为等或低信号改变，T2WI为高信号改变，DWI为等或略高信号改变，ADC 为高信号改变。结论RPLS的发病机制为急性大脑白质血管源性水肿。经积极治疗绝大数RPLS患者预后较好。

    关键词：可逆性后部白质脑病综合征；高血压；子痫；MRI

    Clinical Analysis of 20 Cases of Reversible Posterior Leukoencephalopathy Syndrome

    SHI Fu-hua, LI Shao-cai

    (Zunhua City People's Hospital, Zunhua 064200,Hebei,China)

    Abstract：ObjectiveTo analyze the etiology, clinical features specific and characteristics of magnetic resonance image(MRI) of reversible posterior leukoencephalopathy syndrome(RPLS). MethodsA retrospective analysis about clinical characteristics and MRI was performed in 20 patients with reversible posterior leukoencephalopathy syndrome, summarize the etiology, clinical manifestations and MRI. ResultsHypertension and eclampsia is the most important cause of RPLS ......