PCI患者强化他汀治疗的临床意义及安全性(2)
在本研究中,ACS患者采用强化他汀治疗不仅能减少患者30d不良心血管事件,改善临床结果,而且未见明显的肝酶、肌酶升高,这说明至少短期强化他汀治疗是有效而且安全的。
参考文献:
[1]Navarese EP,Kowalewski M,Andreotti F.Meta-analysis of time-related benefits of statin therapy in patients with acute coronary syndrome undergoing percutaneous coronary intervention[J].Am J Cardiol,2014,113(10):1753-1764.
[2]王彦方,郑晓辉,胡丰朝,等.大剂量阿托伐他汀对PCI术后心肌损伤及预后的影响[J].中国循证心血管医学杂志,2013,1.
[3]赵水平,胡大一.非ST段抬高急性冠脉综合征[J].心血管病诊疗指南解读,2008,10:202-214.
[4]Krintus M1,Kozinski M,Kubica J.Critical appraisal of inflammatory markers in cardiovascular risk stratification[J].Crit Rev Clin Lab Sci,2014,11:1-17.
[5]惠汝太.YELLOW试验概要与解读:强化他汀治疗对动脉硬化斑块成分的影响[J].心脏病学实践,2012:658-659.
[6]Nissen SE, Nicholls SJ,Sipahi I,et al.ASTEROID Investigators[J].JAMA,2006,295:1556-1565.
[7]Mirjanic-Azaric B1,Rizzo M,Sormaz L.Atorvastatin in stable angina patients lowers CCL2 and ICAM1 expression: pleiotropic evidence from plasma mRNA analyses[J].Clin Biochem,2013,46(15):1526-1531.
[8]Deharo P,Pankert M,Quilici J.Safety and effectiveness of the association ezetimibe-statin (E-S) versus high dose rosuvastatin after acute coronary syndrome:The SAFE-ES study[J].Ann Cardiol Angeiol,2014,2.
[9]陈锐,张抒扬.他汀类药物安全性研究进展(心脏病学实践)[M].北京:人民卫生出版社 ,2012:429-433.编辑/成森, http://www.100md.com(杨长宝 郑海军 李爱琴)
参考文献:
[1]Navarese EP,Kowalewski M,Andreotti F.Meta-analysis of time-related benefits of statin therapy in patients with acute coronary syndrome undergoing percutaneous coronary intervention[J].Am J Cardiol,2014,113(10):1753-1764.
[2]王彦方,郑晓辉,胡丰朝,等.大剂量阿托伐他汀对PCI术后心肌损伤及预后的影响[J].中国循证心血管医学杂志,2013,1.
[3]赵水平,胡大一.非ST段抬高急性冠脉综合征[J].心血管病诊疗指南解读,2008,10:202-214.
[4]Krintus M1,Kozinski M,Kubica J.Critical appraisal of inflammatory markers in cardiovascular risk stratification[J].Crit Rev Clin Lab Sci,2014,11:1-17.
[5]惠汝太.YELLOW试验概要与解读:强化他汀治疗对动脉硬化斑块成分的影响[J].心脏病学实践,2012:658-659.
[6]Nissen SE, Nicholls SJ,Sipahi I,et al.ASTEROID Investigators[J].JAMA,2006,295:1556-1565.
[7]Mirjanic-Azaric B1,Rizzo M,Sormaz L.Atorvastatin in stable angina patients lowers CCL2 and ICAM1 expression: pleiotropic evidence from plasma mRNA analyses[J].Clin Biochem,2013,46(15):1526-1531.
[8]Deharo P,Pankert M,Quilici J.Safety and effectiveness of the association ezetimibe-statin (E-S) versus high dose rosuvastatin after acute coronary syndrome:The SAFE-ES study[J].Ann Cardiol Angeiol,2014,2.
[9]陈锐,张抒扬.他汀类药物安全性研究进展(心脏病学实践)[M].北京:人民卫生出版社 ,2012:429-433.编辑/成森, http://www.100md.com(杨长宝 郑海军 李爱琴)