摘要：目的 研究胃癌组织中卵泡刺激素(FSH)及其受体(FSHR)的分布情况及其意义。方法 运用免疫荧光法检测58胃贲门腺癌组织中FSH和FSHR的分布。结果 FSH和FSHR在高分化胃贲门腺癌组织中的表达阳性率分别为69.2%和69.2%，在中分化胃贲门腺癌组织中的表达阳性率分别为37.8%和48.1%，在低分化胃贲门腺癌组织中的表达阳性率分别为27.8%和22.2%。胃贲门腺癌组织中FSH和FSHR表达水平具有相关性(r=0.463，P<0.05)。结论 FSH和FSHR均存在分布于胃贲门腺癌组织中，且分布水平同组织分化程度密切相关，FSH和FSHR分布可能与胃贲门腺癌的生物学行为相关。

    关键词：卵泡刺激素；卵泡刺激素受体；免疫荧光；胃贲门腺癌

    Abstract：Objective To study the distribution and its significance of follicle stimulating hormone (FSH) and it's receptor (FSHR) in human gastric cardia adenocarcinoma. Methods Immunofluorescence histochemical staining and confocal laser scanning microscope were used in in 58 samples .Results The positive rates of FSH and it's receptor were 69.2% and 69.2% in well differentiated gastric cardia adenocarcinoma ......