泮托拉唑和奥美拉唑治疗2型糖尿病并发消化性溃疡出血的对比(1)
摘要:目的 探讨泮托拉唑和奥美拉唑治疗2型糖尿病并发消化性溃疡出血的疗效。方法 收集2012年1月~2015年8月我院诊断为2型糖尿病并发消化性溃疡出血的患者,基础疾病为2型糖尿病。随机分为两组,研究组50例(接受泮托拉唑治疗)和对照组50例(接受奥美拉唑治疗),余治疗方法两组相同。结果 ①研究组和对照组消化性溃疡出血的治愈率分别为96%、82%,结果比较有差异(P<0.05)。②研究组和对照组消化性溃疡出血停止时间分别为(28.2±7.2)h、(35.8±9.2)h,结果比较有差异(P<0.05)。③研究组和对照组用药期间不良反应(恶心、头晕、口干、便秘、皮疹)发生率分别为6%、10%,结果比较无差异(P>0.05)。结论 本次研究认为相对于奥美拉唑,泮托拉唑治疗2型糖尿病并发消化性溃疡出血疗效肯定,能在短期内改善患者症状。
关键词:泮托拉唑;奥美拉唑;2型糖尿病;消化性溃疡;出血
Comparison of Type 2 Diabetes Mellitus Complicated with Peptic Ulcer Hemorrhage Treated with Pantoprazole and Omeprazole
, http://www.100md.com
PANG Xue-hua
(The First People's Hospital of Shuangliu District,Chengdu 610200,Sichuan,China)
Abstract:Objective To investigate the curative effect of pantoprazole and omeprazole in the treatment of diabetes mellitus complicated with peptic ulcer bleeding type 2.Methods Collected in August January 2012-2015 in our hospital diagnosed type 2 diabetes mellitus complicated with peptic ulcer bleeding in patients with basic disease for type 2 diabetes.Were randomly divided into 2 groups,the study group 50 cases(received pantoprazole treatment)and the control group(50 cases)received omeprazole,Yu treatment two groups of the same.Results ①The cure rate of peptic ulcer bleeding in the study group and the control group were 96%and 82%,respectively,and the results were quite different(P<0.05).②In the study group and control group,the bleeding time of peptic ulcer bleeding was 28.2±7.2 hours,35.8±9.2 hours,and the results were quite different(P<0.05).③In the study group and control group,medication period adverse effects(nausea,dizziness,dry mouth,constipation,skin rash,occurrence rate of 6%and 10%respectively.As a result,there is no significant difference(P>0.05).Conclusion This study that compared with omeprazole,pantoprazole in treatment of type 2 diabetes mellitus complicated with digestive ulcer hemorrhage curative effect,can improve the symptoms in the short term.
, 百拇医药
Key words:Pantoprazole;Omeprazole;Type 2 diabetes;Peptic ulcer;Hemorrhage
泮托拉唑和奥美拉唑同为质子泵抑制剂,在临床上广泛用于消化道溃疡的治疗。因此本次研究拟收集2012年1月~2015年8月我院诊断为2型糖尿病并发消化性溃疡出血的患者,探讨泮托拉唑和奥美拉唑的治疗差异。
1 资料与方法
1.1一般资料 收集2012年1月~2015年8月我院诊断为2型糖尿病并发消化性溃疡出血的患者,基础疾病为2型糖尿病。随机分为两组,研究组50例(接受泮托拉唑治疗)和对照组50例(接受奥美拉唑治疗),余治疗方法两组相同。研究组平均年龄(58.3±16.8)岁,其中男性28例,女性22例;对照组平均年龄(52.9±17.9)岁,其中男性27例,女性23例。两组人员性别,年龄,疾病类型上差异无统计学意义。
1.2入选标准 ①2型糖尿病诊断符合第8版《实用内科学》制定的标准;②消化性溃疡符合第8版《实用内科学》制定的标准,有呕血或呕吐咖啡样物与黑便,呕吐物隐血或大便隐血阳性,胃镜检查支持。③肝肾功能正常。
1.3排除指标 对本次研究药品过敏者。, http://www.100md.com(庞雪花)
关键词:泮托拉唑;奥美拉唑;2型糖尿病;消化性溃疡;出血
Comparison of Type 2 Diabetes Mellitus Complicated with Peptic Ulcer Hemorrhage Treated with Pantoprazole and Omeprazole
, http://www.100md.com
PANG Xue-hua
(The First People's Hospital of Shuangliu District,Chengdu 610200,Sichuan,China)
Abstract:Objective To investigate the curative effect of pantoprazole and omeprazole in the treatment of diabetes mellitus complicated with peptic ulcer bleeding type 2.Methods Collected in August January 2012-2015 in our hospital diagnosed type 2 diabetes mellitus complicated with peptic ulcer bleeding in patients with basic disease for type 2 diabetes.Were randomly divided into 2 groups,the study group 50 cases(received pantoprazole treatment)and the control group(50 cases)received omeprazole,Yu treatment two groups of the same.Results ①The cure rate of peptic ulcer bleeding in the study group and the control group were 96%and 82%,respectively,and the results were quite different(P<0.05).②In the study group and control group,the bleeding time of peptic ulcer bleeding was 28.2±7.2 hours,35.8±9.2 hours,and the results were quite different(P<0.05).③In the study group and control group,medication period adverse effects(nausea,dizziness,dry mouth,constipation,skin rash,occurrence rate of 6%and 10%respectively.As a result,there is no significant difference(P>0.05).Conclusion This study that compared with omeprazole,pantoprazole in treatment of type 2 diabetes mellitus complicated with digestive ulcer hemorrhage curative effect,can improve the symptoms in the short term.
, 百拇医药
Key words:Pantoprazole;Omeprazole;Type 2 diabetes;Peptic ulcer;Hemorrhage
泮托拉唑和奥美拉唑同为质子泵抑制剂,在临床上广泛用于消化道溃疡的治疗。因此本次研究拟收集2012年1月~2015年8月我院诊断为2型糖尿病并发消化性溃疡出血的患者,探讨泮托拉唑和奥美拉唑的治疗差异。
1 资料与方法
1.1一般资料 收集2012年1月~2015年8月我院诊断为2型糖尿病并发消化性溃疡出血的患者,基础疾病为2型糖尿病。随机分为两组,研究组50例(接受泮托拉唑治疗)和对照组50例(接受奥美拉唑治疗),余治疗方法两组相同。研究组平均年龄(58.3±16.8)岁,其中男性28例,女性22例;对照组平均年龄(52.9±17.9)岁,其中男性27例,女性23例。两组人员性别,年龄,疾病类型上差异无统计学意义。
1.2入选标准 ①2型糖尿病诊断符合第8版《实用内科学》制定的标准;②消化性溃疡符合第8版《实用内科学》制定的标准,有呕血或呕吐咖啡样物与黑便,呕吐物隐血或大便隐血阳性,胃镜检查支持。③肝肾功能正常。
1.3排除指标 对本次研究药品过敏者。, http://www.100md.com(庞雪花)