连续血液净化用于重症脓毒症治疗疗效观察(1)
摘要：目的 对重症脓毒症患者予以连续血液净化治疗的临床效果进行剖析。方法 遵循随机原则选取2014年9月～2015年9月于我院接受诊疗的重症脓毒症患者76例，并将其以每组38例平均分为普通组与特殊组。给予普通组患者进行常规治疗，对特殊组患者则在前者治理基础上进行连续血液净化，然后对两组患者的临床表现和疗效进行记录与比较。结果 特殊组患者痊愈21例，改善17例，不存在失效病例，临床总有效率为100.00%；而普通组患者痊愈11例，改善18例，失效9例，临床总有效率为76.32%，前者疗效明显大于后者，且两者数据差异具有统计学意义(P<0.05)。同时，特殊组与普通组患者在各项生命指标和不良反应发生情况两方面上均存在统计学差异(前者优于后者，P<0.05)。结论 采用常規治疗结合连续血液净化对重症脓毒症患者进行深入治疗，除可获得理想的疗效外，亦可同时抑制不良反应的发生，值得大力推广。
关键词：连续血液净化；重症脓毒症；疗效
Continuous Blood Purification for the Treatment of Severe Sepsis
, 百拇医药
SUN Han-gao
(ICU，Dazhu County People's Hospital，Dazhu 635100， Sichuan，China)
Abstract：Objective To patients with severe sepsis by continuous blood purification treatment of the clinical effect were analyzed. Methods According to randomly selected from September 2014 to September 2015 in our hospital 76 patients with severe sepsis in the diagnosis and treatment of patients， and to 38 cases in each group were divided into normal group and special groups of patients were given normal group. The routine treatment， patients in the former group of special governance on the basis of continuous blood purification， and then compared with the records of clinical manifestations and curative effect of two groups of patients.Results The special group of 21 cases were cured， 17 cases improved， there is no failure cases， the total clinical effective rate was 100 .00%； normal group 11 cases were cured， 18 cases improved， 9 cases ineffective， the total clinical effective rate was 76.32%， the former is significantly larger than the latter， and there was a significant difference between the two data (P<0.05). At the same time， the special group and common group of patients in the life index and adverse reaction incidence there were statistically significant differences two aspects (the former is better than the latter， P<0.05). Conclusion The routine treatment of continuous blood purification for further treatment of patients with severe sepsis in combination， can achieve ideal curative effect， can also inhibit the occurrence of adverse reactions， it is worth popularizing.
, 百拇医药
Key words：Continuous blood purification； Severe sepsis； Curative effect
医学上将由感染所引发的全身性炎症反应综合征称为脓毒症，且据临床科学研究表明其不仅存在细菌而且亦具有高度可疑感染灶，严重危害人类健康，是导致近年来重症监护病房患者死亡率逐步上升的主要疾病之一[1-2]。就脓毒症的发病根源而言，大多数均由感染所引起，但该疾病一经发生，其后期均按其自身的发展规律以及病理过程进行进一步恶化，因此，患者机体对感染性因素所产生的反应才是脓毒症的本质。本文就对重症脓毒症患者采用常规治疗与连续血液净化相结合进行治疗的效果予以详细剖析，现作如下报告。
1资料与方法
1.1一般资料 从我院于2014年9月～2015年9月接收并予以治疗的重症脓毒症患者76例，在患者自愿参加本次研究的前提下，将其分为普通组与特殊组，每组38例。其中普通组女患者有18例，男患者有20例；年龄20～76岁，平均年龄(60.22±1.38)岁；腹腔感染13例，消化系统感染10例，肺部感染15例；特殊组女患者17例，男患者21例；年龄19～77岁，平均年龄(60.39±1.58)岁；腹腔感染14例，消化系统感染8例，肺部感染16例。结合两组重症脓毒症患者的基本信息(性别、年龄、感染类型)并进行科学对比分析，发现两者基本信息差异均不存在统计学意义(P>0.05)，具备可比性。, 百拇医药(孙晗高)
关键词：连续血液净化；重症脓毒症；疗效
Continuous Blood Purification for the Treatment of Severe Sepsis
, 百拇医药
SUN Han-gao
(ICU，Dazhu County People's Hospital，Dazhu 635100， Sichuan，China)
Abstract：Objective To patients with severe sepsis by continuous blood purification treatment of the clinical effect were analyzed. Methods According to randomly selected from September 2014 to September 2015 in our hospital 76 patients with severe sepsis in the diagnosis and treatment of patients， and to 38 cases in each group were divided into normal group and special groups of patients were given normal group. The routine treatment， patients in the former group of special governance on the basis of continuous blood purification， and then compared with the records of clinical manifestations and curative effect of two groups of patients.Results The special group of 21 cases were cured， 17 cases improved， there is no failure cases， the total clinical effective rate was 100 .00%； normal group 11 cases were cured， 18 cases improved， 9 cases ineffective， the total clinical effective rate was 76.32%， the former is significantly larger than the latter， and there was a significant difference between the two data (P<0.05). At the same time， the special group and common group of patients in the life index and adverse reaction incidence there were statistically significant differences two aspects (the former is better than the latter， P<0.05). Conclusion The routine treatment of continuous blood purification for further treatment of patients with severe sepsis in combination， can achieve ideal curative effect， can also inhibit the occurrence of adverse reactions， it is worth popularizing.
, 百拇医药
Key words：Continuous blood purification； Severe sepsis； Curative effect
医学上将由感染所引发的全身性炎症反应综合征称为脓毒症，且据临床科学研究表明其不仅存在细菌而且亦具有高度可疑感染灶，严重危害人类健康，是导致近年来重症监护病房患者死亡率逐步上升的主要疾病之一[1-2]。就脓毒症的发病根源而言，大多数均由感染所引起，但该疾病一经发生，其后期均按其自身的发展规律以及病理过程进行进一步恶化，因此，患者机体对感染性因素所产生的反应才是脓毒症的本质。本文就对重症脓毒症患者采用常规治疗与连续血液净化相结合进行治疗的效果予以详细剖析，现作如下报告。
1资料与方法
1.1一般资料 从我院于2014年9月～2015年9月接收并予以治疗的重症脓毒症患者76例，在患者自愿参加本次研究的前提下，将其分为普通组与特殊组，每组38例。其中普通组女患者有18例，男患者有20例；年龄20～76岁，平均年龄(60.22±1.38)岁；腹腔感染13例，消化系统感染10例，肺部感染15例；特殊组女患者17例，男患者21例；年龄19～77岁，平均年龄(60.39±1.58)岁；腹腔感染14例，消化系统感染8例，肺部感染16例。结合两组重症脓毒症患者的基本信息(性别、年龄、感染类型)并进行科学对比分析，发现两者基本信息差异均不存在统计学意义(P>0.05)，具备可比性。, 百拇医药(孙晗高)