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腹腔镜手术治疗合并肝硬化胆囊结石疗效及安全性评价(1)
http://www.100md.com 2017年1月15日 《医学信息》 2017年第2期
     摘要:目的 探究临床治疗肝硬化并发胆囊结石患者的过程中,应用腹腔镜治疗,分析其临床治疗效果,评价其安全性,为临床肝胆治疗奠定基础。方法 自我院2014年6月~2015年12月收治的64例肝硬化并发胆囊结石患者,对比患者应用不同治疗方案进行治疗,观察临床疗效。结果 予以不同治疗方案后,对试验组患者采用腹腔镜治疗的各项临床指标均显著优于对照组,如出血量、手术、术后排气及住院时间等,差异显著(P<0.05)。对试验组患者采用腹腔镜治疗的术后7 d各项生化指标显著优于对照组,如TBIL、ALT、PT等,差异显著(P<0.05)。且试验组患者采用腹腔镜治疗的并发症发生率(3.12%,1/32)显著低于对照组(18.75%,6/32),差异显著(P<0.05)。结论 临床治疗肝硬化并发胆囊结石患者的过程中,腹腔镜治疗可显著改善患者的各项临床指标,加速患者的康复,具有较好的安全性,应广泛推广。

    关键词:词

    Efficacy and Safety Evaluation of Laparoscopic Surgery in the Treatment of Gallbladder Stone with Cirrhosis
, http://www.100md.com
    TANG Fan

    (Dazhu County People's Hospital,Dazhu 635100,Sichuan,China)

    Abstract:Objective To explore the clinical treatment of liver cirrhosis complicated with gallstones, laparoscopic treatment, analyze the clinical treatment effect, to evaluate the safety and treatment and lay the foundation for the clinical hepatobiliary.Methods 64 cases of liver from June 2014 self hospital in ~2015 December during the hardening of cholecystolithiasis patients, were treated with different treatment regimens were compared the application and clinical observation. Results Different treatments, the test group were treated by laparoscopic treatment of the clinical indicators were significantly better than the control group, such as bleeding, surgery, postoperative exhaust time and hospitalization time, significant difference (P < 0 .05). The test group was treated with laparoscopic treatment of postoperative 7 days control group was better than that of biochemical indexes, such as TBIL, ALT, PT, significant difference (P< 0.05). And the test group were treated by laparoscopic treatment of the complication rate (3.12%, 1/32) was significantly lower than the control group (18.75%, 6/32), significant difference (P< 0.05).Conclusion The clinical treatment of liver cirrhosis complicated with gallstones,laparoscopic treatment can significantly improve clinical indexes of patients,accelerate rehabilitation,with better security,should be widely promoted.
, 百拇医药
    Key words:Liver cirrhosis;Gallbladder stone;Laparoscopy;Effect;Safety

    作为普外科常见病变之一的胆囊结石,其发病率较高,尤其是在肝硬化患者,其发病率更高,高于正常人的2~5倍[1]。就胆囊结石合并肝硬化患者来讲,因肝硬化患者自身肝脏储备功能降低、存在门脉高压和凝血机制异常等,因此在一定程度上也加大了胆囊切除的难度[2]。且肝硬化与胆囊结石可以互相影响,形成恶性循环。近些年,随着医学技术的发展与完善,腹腔镜治疗已攻破这一难题。为此,本研究旨在临床治疗肝硬化并发胆囊结石患者的过程中,应用腹腔镜治疗,分析其临床治疗效果,为临床肝胆治疗奠定基礎,以下是详细报道。

    1资料与方法

    1.1一般资料 自我院2014年6月~2015年12月收治的肝硬化并发胆囊结石患者,随机抽取64例作为本研究对象。男性39例,25例;年龄30~65岁,平均年龄(55.12±4.76)岁。将128例研究对象随机分为试验组和对照组各32例,对比两组患者的一般资料,无差异(P>0.05)。, 百拇医药(唐凡)
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