单纯回输洗涤式自体血在不停跳冠状动脉搭桥术中的应用(3)
目前临床上尚不能检测库血中所有病原体及窗口期感染的血液制品,输异体血费用较高,并且库存血中钾离子浓度较高,可能会引起电解质紊乱及心肌抑制作用,大量研究指出异体输血对心脏手术患者远期生存有负面影响,远期病死率明显增加[8-9]。Cell Savor回收的血源通常不需要转运、配型,无需组织相容性及疾病检验,几乎避免了严重输血反应。回收的洗涤红细胞较库血2,3-DPG的含量高,释放氧的能力较强,有较好的氧运输能力[10]。围手术期单纯回输洗涤式自体血在不停跳冠状动脉搭桥术中的应用可纠正贫血,减少异体输血量,对节省血液应用有重要意义,对患者的凝血功能和术后恢复无明显不良影响,能够降低住院费用,可应用于临床。
参考文献:
[1]Tomoaki S,Tohru A.The current status of multi-arterial off-pump coronary artery bypass grafting[J].Surg Today,2016,46(1):1-12.
[2]曹学照,方波,马虹.术中洗涤式自体血回输对患者凝血功能影响的临床观察[J].中国输血杂志,2008(11):860-861.
[3]Ascione R,Williams S,Lloyd CT,et al.Reduced postoperative blood loss and transfusion requirement after beating-heart coronary operations: a prospective randomized study[J].J Thorac Cardiovasc Surg,2001,121(4):689-96.
[4]邱莉,卿恩明,马骏.120例回收式自体输血在非停跳冠状动脉旁路移植术中的临床应用分析[J].心肺血管病杂志,2013,32(5):604-607.
[5]李丹,闫玉生,蒙华,等.在心脏手术中采用自体血回收能否节约用血[J].透析与人工器官,2011(01):14-18.
[6]Kiaii B,Fox S,Swinamer SA,et al.The early inflammatory response in a mini-cardiopulmonary bypass system:a prospective randomized study[J].Innovations,2012,7(1):23-32.
[7]Gabel J,Westerberg M,Bengtsson A,et al.Cell salvage of cardiotomy suction blood improves the balance between pro- and anti-inflammatory cytokines after cardiac surgery[J].Eur J Cardiothorac Surg,2013,44(3): 506-11.
[8]Mikkola R,Heikkinen J,Lahtinen J,et al.Does blood transfusion affect intermediate survival after coronary artery bypass surgery[J].Scand J Surg, 2013,102(2):110-6.
[9]Likosky DS,Paone G,Zhang M,et al.Red Blood Cell Transfusions Impact Pneumonia Rates After Coronary Artery Bypass Grafting[J].Ann Thorac Surg,2015,100(3):794-801.
[10]Scott AV,Nagababu E,Johnson DJ,et al.2,3-Diphosphoglycerate Concentrations in Autologous Salvaged Versus Stored Red Blood Cells and in Surgical Patients After Transfusion[J].Anesth Analg,2016,122(3): 616-23.
編辑/成森, 百拇医药(王海洋 葛建军)
参考文献:
[1]Tomoaki S,Tohru A.The current status of multi-arterial off-pump coronary artery bypass grafting[J].Surg Today,2016,46(1):1-12.
[2]曹学照,方波,马虹.术中洗涤式自体血回输对患者凝血功能影响的临床观察[J].中国输血杂志,2008(11):860-861.
[3]Ascione R,Williams S,Lloyd CT,et al.Reduced postoperative blood loss and transfusion requirement after beating-heart coronary operations: a prospective randomized study[J].J Thorac Cardiovasc Surg,2001,121(4):689-96.
[4]邱莉,卿恩明,马骏.120例回收式自体输血在非停跳冠状动脉旁路移植术中的临床应用分析[J].心肺血管病杂志,2013,32(5):604-607.
[5]李丹,闫玉生,蒙华,等.在心脏手术中采用自体血回收能否节约用血[J].透析与人工器官,2011(01):14-18.
[6]Kiaii B,Fox S,Swinamer SA,et al.The early inflammatory response in a mini-cardiopulmonary bypass system:a prospective randomized study[J].Innovations,2012,7(1):23-32.
[7]Gabel J,Westerberg M,Bengtsson A,et al.Cell salvage of cardiotomy suction blood improves the balance between pro- and anti-inflammatory cytokines after cardiac surgery[J].Eur J Cardiothorac Surg,2013,44(3): 506-11.
[8]Mikkola R,Heikkinen J,Lahtinen J,et al.Does blood transfusion affect intermediate survival after coronary artery bypass surgery[J].Scand J Surg, 2013,102(2):110-6.
[9]Likosky DS,Paone G,Zhang M,et al.Red Blood Cell Transfusions Impact Pneumonia Rates After Coronary Artery Bypass Grafting[J].Ann Thorac Surg,2015,100(3):794-801.
[10]Scott AV,Nagababu E,Johnson DJ,et al.2,3-Diphosphoglycerate Concentrations in Autologous Salvaged Versus Stored Red Blood Cells and in Surgical Patients After Transfusion[J].Anesth Analg,2016,122(3): 616-23.
編辑/成森, 百拇医药(王海洋 葛建军)