血液透析治疗肾病综合征急性肾功能衰竭的临床效果观察(1)
摘要：目的 观察血液透析治疗肾病综合征急性肾功能衰竭的临床效果。方法 选取我院2013年6月～2015年5月收治的62例肾病综合征急性肾功能衰竭患者，采用随机数字表法分为对照组和观察组。对照组患者采用常规治疗，观察组患者在此基础上加用血液透析治疗。对比两组患者治疗前后血清肌酐、内生肌酐以及尿素氮水平变化情况；并将两组患者住院时间与并发症发生率进行比较；出院后对所有患者均进行1年的随访，对比1年内两组患者的死亡率。结果 治疗前两组患者血清肌酐、内生肌酐以及尿素氮水平比较无明显差异(P<0.05)，治疗后两组患者血清肌酐、内生肌酐以及尿素氮水平明显改善(P<0.05)，但观察组患者的改善情况显著优于对照组(P<0.05)；且观察组患者住院时间更短，并发症发生率更低，与对照组患者相比，差异显著(P<0.05)；随访1年发现，观察组患者的死亡率明显低于对照组(P<0.05)。结论 血液透析治疗肾病综合征急性肾功能衰竭临床效果显著，可有效改善患者血清肌酐、内生肌酐以及尿素氮等指标水平，有利于缩短住院时间，降低并发症发生率，且生存率较高，值得在临床中推广应用。
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关键词：血液透析；肾病综合征；急性肾功能衰竭；临床效果
Abstract：Objective To observe the clinical effect of hemodialysis in the treatment of nephrotic syndrome with acute renal failure.Methods 62 cases of nephrotic in our hospital during June 2013～2015 May were integrated patients with acute renal failure were randomly divided into control group and observation group.The control group was treated with conventional therapy，patients in the observation group on the basis of with the treatment of hemodialysis.Serum creatinine before and after treatment were compared between two groups，creatinine and urea nitrogen level changes；and two groups of patients hospitalized time and complications rate were compared；All patients were followed up for 1 year after discharge，compared with 1 year mortality rate.Results Before treatment two serum creatinine，creatinine and urea nitrogen levels were no significant difference(P<0.05)，two groups after the treatment，serum creatinine，creatinine and urea nitrogen levels were significantly changed(P<0.05)，but the observation group improved significantly better than the control group(P<0.05)；the observation group patients with a shorter hospital stay，the complication rate is lower， compared with the control group，the difference was significant(P<0.05)；1 years of follow-up， patients in the observation group the mortality rate was significantly lower than the control group(P<0.05).Conclusion The clinical effect of hemodialysis in the treatment of nephrotic syndrome with acute renal failure is significant，which can effectively improve the patients with serum creatinine，creatinine and urea nitrogen levels，can shorten the hospitalization time，reduce the incidence of complications，and the survival rate is high，it is worth in clinical application.
Key words：Hemodialysis；Nephrotic syndrome；Acute renal failure；Clinical effect
腎病综合征是指各种原因导致的肾小球基膜通透性增加、肾小球滤过率降低等以肾小球病变为特征的症状[1]。急性肾功能衰竭是肾内科常见病症之一，具有起病急、进展快、病情危重、死亡率高等特点[2]。血液透析是临床中治疗肾病的主要方法之一，经长期临床试验表明，其治疗效果较好。本文将我院收治的62例肾病综合征急性肾功能衰竭患者作为研究对象，观察血液透析治疗肾病综合征急性肾功能衰竭的临床效果，现报告如下。, 百拇医药(章慧)
, http://www.100md.com
关键词：血液透析；肾病综合征；急性肾功能衰竭；临床效果
Abstract：Objective To observe the clinical effect of hemodialysis in the treatment of nephrotic syndrome with acute renal failure.Methods 62 cases of nephrotic in our hospital during June 2013～2015 May were integrated patients with acute renal failure were randomly divided into control group and observation group.The control group was treated with conventional therapy，patients in the observation group on the basis of with the treatment of hemodialysis.Serum creatinine before and after treatment were compared between two groups，creatinine and urea nitrogen level changes；and two groups of patients hospitalized time and complications rate were compared；All patients were followed up for 1 year after discharge，compared with 1 year mortality rate.Results Before treatment two serum creatinine，creatinine and urea nitrogen levels were no significant difference(P<0.05)，two groups after the treatment，serum creatinine，creatinine and urea nitrogen levels were significantly changed(P<0.05)，but the observation group improved significantly better than the control group(P<0.05)；the observation group patients with a shorter hospital stay，the complication rate is lower， compared with the control group，the difference was significant(P<0.05)；1 years of follow-up， patients in the observation group the mortality rate was significantly lower than the control group(P<0.05).Conclusion The clinical effect of hemodialysis in the treatment of nephrotic syndrome with acute renal failure is significant，which can effectively improve the patients with serum creatinine，creatinine and urea nitrogen levels，can shorten the hospitalization time，reduce the incidence of complications，and the survival rate is high，it is worth in clinical application.
Key words：Hemodialysis；Nephrotic syndrome；Acute renal failure；Clinical effect
腎病综合征是指各种原因导致的肾小球基膜通透性增加、肾小球滤过率降低等以肾小球病变为特征的症状[1]。急性肾功能衰竭是肾内科常见病症之一，具有起病急、进展快、病情危重、死亡率高等特点[2]。血液透析是临床中治疗肾病的主要方法之一，经长期临床试验表明，其治疗效果较好。本文将我院收治的62例肾病综合征急性肾功能衰竭患者作为研究对象，观察血液透析治疗肾病综合征急性肾功能衰竭的临床效果，现报告如下。, 百拇医药(章慧)
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