女性不稳定性心绞痛临床特征的回顾性分析(1)
摘要：目的 探討女性不稳定性心绞痛(UA)患者的临床特征。方法 连续收集2014年7月～2016年6月符合入选条件的住院UA病例968例，按照女性组403例和男性组565例及其年龄段统计相关的临床资料，回顾性分析UA患者冠心病的常见危险因素、主要临床表现、诊断类型和危险程度。结果 女性组UA患者发病年龄较男性组晚6.31年(P<0.01)，高血压、高脂血症总体比例高于男性(P<0.05)，糖尿病在各个年龄段和总体比例上均高于男性(P<0.01)，主动吸烟则低于男性(P<0.01)。女性组除60～69岁年龄段外，非典型性胸痛比例均高于男性组(P<0.01)，初发劳力性心绞痛随年龄增长而明显降低，总体比例仍高于男性组(P<0.01)，恶化劳力性心绞痛随着年龄增长而增多，总体比例低于男性组(P<0.05)。心律失常比例低于男性组(P<0.01)。女性组左室射血分数、左心室收缩末内径、左心室舒张末内径、左心房内径以及氨基末端B型利钠肽与男性组差异具有统计学意义(P<0.05)。结论 女性UA患者发病年龄晚，高血压、糖尿病、高脂血症等危险因素比例高，而且常常呈群集性。不典型胸痛多见，增加了临床诊断难度。初发劳力性心绞痛与年龄呈负相关，而恶化劳力性心绞痛与年龄呈正相关。随年龄增长，女性UA患者的危险程度明显升高，逐渐接近男性UA患者的危险程度。
, 百拇医药
关键词：女性；冠心病；不稳定性心绞痛；临床特点
中图分类号：R541.4 文献标识码：A 文章编号：1006-1959(2017)14-0060-05
A Retrospective Analysis of the Clinical Features of Female Unstable Angina Pectoris
ZHOU Hui1，ZHOU Mao-feng1，HUAN Qiang2，WANG Zhi-jing2，DI Yong1，LUO Jun2，ZHA Wu-hao1
(1.Department of Emergency Medicine，Zhoupu Hospital，Pudong New Area，Shanghai 201318，China；
, 百拇医药
2.Department of Cardiology，Zhoupu Hospital，Pudong New Area，Shanghai 201318，China)
Abstract：Objective To investigate the women with unstable angina pectoris(UA)patients with clinical features.Methods Collected July 2014～2016 year in June were eligible in 968 cases of UA patients，according to the 403 cases of female group and male group 565 cases and age related clinical data statistics，review of the common risk factors of coronary heart disease in patients with UA，the main clinical diagnostic performance，type and degree of risk.Results The female group UA patients aged 6.31 years later than the male group(P<0.01)，hypertension，hyperlipidemia population proportion is higher than the male (P<0.05)，diabetes was higher than that of men in all ages and the overall proportion(P<0.01)，active smoking is less than male(P<0.01). In addition to female group aged 60～69，atypical chest pain was higher than the proportion of male group(P<0.01)，primary exertional angina with age significantly reduced，the overall proportion is still higher than the male group(P<0.01)，exertional angina increased with age，the overall proportion is lower than the male group(P<0.05).The arrhythmia ratio is lower than the male group(P<0.01).The left ventricular ejection fraction，left ventricular end-diastolic diameter，left ventricular diastolic diameter，left atrial diameter and amino-terminal B-type natriuretic peptide were significantly different from those in the male group(P<0.05).Conclusion Female UA patients with late age，high blood pressure，diabetes，hyperlipidemia and other risk factors are high，and often clustered.Atypical chest pain more common， increasing the difficulty of clinical diagnosis.Initial onset of angina pectoris was negatively correlated with age，and exacerbated labor angina was positively correlated with age.With age，the risk of female UA patients was significantly higher， gradually close to the risk of male UA patients., http://www.100md.com(周辉 周茂峰 郇强 王志敬 狄勇 罗俊 查吴浩)
, 百拇医药
关键词：女性；冠心病；不稳定性心绞痛；临床特点
中图分类号：R541.4 文献标识码：A 文章编号：1006-1959(2017)14-0060-05
A Retrospective Analysis of the Clinical Features of Female Unstable Angina Pectoris
ZHOU Hui1，ZHOU Mao-feng1，HUAN Qiang2，WANG Zhi-jing2，DI Yong1，LUO Jun2，ZHA Wu-hao1
(1.Department of Emergency Medicine，Zhoupu Hospital，Pudong New Area，Shanghai 201318，China；
, 百拇医药
2.Department of Cardiology，Zhoupu Hospital，Pudong New Area，Shanghai 201318，China)
Abstract：Objective To investigate the women with unstable angina pectoris(UA)patients with clinical features.Methods Collected July 2014～2016 year in June were eligible in 968 cases of UA patients，according to the 403 cases of female group and male group 565 cases and age related clinical data statistics，review of the common risk factors of coronary heart disease in patients with UA，the main clinical diagnostic performance，type and degree of risk.Results The female group UA patients aged 6.31 years later than the male group(P<0.01)，hypertension，hyperlipidemia population proportion is higher than the male (P<0.05)，diabetes was higher than that of men in all ages and the overall proportion(P<0.01)，active smoking is less than male(P<0.01). In addition to female group aged 60～69，atypical chest pain was higher than the proportion of male group(P<0.01)，primary exertional angina with age significantly reduced，the overall proportion is still higher than the male group(P<0.01)，exertional angina increased with age，the overall proportion is lower than the male group(P<0.05).The arrhythmia ratio is lower than the male group(P<0.01).The left ventricular ejection fraction，left ventricular end-diastolic diameter，left ventricular diastolic diameter，left atrial diameter and amino-terminal B-type natriuretic peptide were significantly different from those in the male group(P<0.05).Conclusion Female UA patients with late age，high blood pressure，diabetes，hyperlipidemia and other risk factors are high，and often clustered.Atypical chest pain more common， increasing the difficulty of clinical diagnosis.Initial onset of angina pectoris was negatively correlated with age，and exacerbated labor angina was positively correlated with age.With age，the risk of female UA patients was significantly higher， gradually close to the risk of male UA patients., http://www.100md.com(周辉 周茂峰 郇强 王志敬 狄勇 罗俊 查吴浩)
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