不同剂量甲强龙用于小儿重症支原体肺炎的临床效果观察(1)
摘要：目的 着重于探讨重症支原体肺炎患儿运用不同剂量甲强龙治疗的临床效果。方法 对80例本院收治的重症支原体肺炎患儿随机分为实验组与对照组各40例。对照组采用2 mg/kg甲强龙治疗，实验组采用20 mg/kg甲强龙治疗，比较两组临床指标、生活质量与治疗总有效率。结果 实验组生活质量评分为(9.2±0.3)分，胸片恢复时间为(7.5±1.9)d，肺啰音消失时间为(6.1±2.3)d，退热时间为(0.4±0.2)d，止咳时间为(5.6±1.5)d，治疗总有效率为97.50%，对照组生活质量评分、胸片恢复时间、肺啰音消失时间、退热时间、止咳时间与治疗总有效率分别为(6.4±0.5)分、(14.5±5.2)d、(8.3±1.5)d、(3.2±1.3)d、(7.5±2.2)d、72.50%，实验组均明显优于对照组，差异显著(P<0.05)，具有统计学意义。结论 大剂量甲强龙治疗小儿重症支原体肺炎效果确切，症状能够迅速消退，临床应用价值极高。
关键词：重症支原体肺炎；甲强龙；生活质量；临床指标
, http://www.100md.com
中图分类号：R725.6 文献标识码：A 文章编号：1006-1959(2017)18-0082-03
Abstract：Objective To investigate the clinical efficacy of different doses of methylprednisolone in the treatment of severe mycoplasma pneumonia. Methods 80 cases of severe mycoplasma pneumonia in our hospital were randomly divided into the experimental group and the control group，each with 40 cases.The control group was treated with 2 mg/kg methylprednisolone.The experimental group was treated with 20 mg/kg methylprednisolone. The clinical indexes，quality of life and total effective rate were compared.Results The quality of life of the experimental group was(9.2±0.3)，Chest X-ray recovery time(7.5±1.9)d，pulmonary rales disappeared time was(6.1±2.3)d，antifebrile time was (0.4±0.2)d，cough treatment time is(5.6±1.5)d，the total effective rate was 97.50%，the control group quality of life score，chest X-ray recovery time，pulmonary rales disappeared time，antifebrile time，cough treatment time and total effective rate were(6.4±0.5)，(14.5±5.2)d，(8.3±1.5)d，(3.2±1.3)d，(7.5±2.2)d，72.50%，the experimental group were significantly better than the control group，the difference was significant(P<0.05)，with statistical significance.Conclusion Large dose of methylprednisolone in the treatment of severe mycoplasma pneumonia in children has definite effect，the symptoms can rapidly subside，and the clinical application value is very high.
, 百拇医药
Key words：Severe mycoplasma pneumonia；Methylprednisolone；Quality of life；Clinical indicators
支原體肺炎为临床中最为常见的小儿高发性疾病，也能是社区获得性肺炎，其主要病原是肺炎支原体，存在极高的发病率，治疗方面有一些难度[1-2]。针对小儿重症支原体肺炎应用常规剂量甲强龙往往很难取得良好的应用成效，但是通过合理的加大剂量能够获得令人满意的临床效果[3]。在此背景下，我科选取了80例曾在我院接受治疗的重症支原体肺炎患儿，分别给予了不同剂量的甲强龙治疗，从而深入讨论大剂量甲强龙对其临床指标、治疗总有效率与生活质量的影响，具体报告如下：
1资料与方法
1.1 一般资料
资料来源于本院2015年2月～2017年3月收治的重症支原体肺炎患儿80例，按随机数字法将其分为实验组和对照组，每组各40例。实验组中，男22例，女18例；年龄3～8岁，平均年龄(6.1±2.5)岁；病程9～21 d，平均病程(14.3±4.2)d；体重12～28 kg，平均体重(18.2±4.1)kg。对照组中，女16例，男24例；年龄3～9岁，平均年龄(6.3±2.6)岁；病程9～22 d，平均病程(14.6±4.3)d；体重13～28 kg，平均体重(18.5±4.2)kg。实验组患儿的基本资料与对照组差异不显著(P>0.05)，可用于本次研究。, http://www.100md.com(魏众新)
关键词：重症支原体肺炎；甲强龙；生活质量；临床指标
, http://www.100md.com
中图分类号：R725.6 文献标识码：A 文章编号：1006-1959(2017)18-0082-03
Abstract：Objective To investigate the clinical efficacy of different doses of methylprednisolone in the treatment of severe mycoplasma pneumonia. Methods 80 cases of severe mycoplasma pneumonia in our hospital were randomly divided into the experimental group and the control group，each with 40 cases.The control group was treated with 2 mg/kg methylprednisolone.The experimental group was treated with 20 mg/kg methylprednisolone. The clinical indexes，quality of life and total effective rate were compared.Results The quality of life of the experimental group was(9.2±0.3)，Chest X-ray recovery time(7.5±1.9)d，pulmonary rales disappeared time was(6.1±2.3)d，antifebrile time was (0.4±0.2)d，cough treatment time is(5.6±1.5)d，the total effective rate was 97.50%，the control group quality of life score，chest X-ray recovery time，pulmonary rales disappeared time，antifebrile time，cough treatment time and total effective rate were(6.4±0.5)，(14.5±5.2)d，(8.3±1.5)d，(3.2±1.3)d，(7.5±2.2)d，72.50%，the experimental group were significantly better than the control group，the difference was significant(P<0.05)，with statistical significance.Conclusion Large dose of methylprednisolone in the treatment of severe mycoplasma pneumonia in children has definite effect，the symptoms can rapidly subside，and the clinical application value is very high.
, 百拇医药
Key words：Severe mycoplasma pneumonia；Methylprednisolone；Quality of life；Clinical indicators
支原體肺炎为临床中最为常见的小儿高发性疾病，也能是社区获得性肺炎，其主要病原是肺炎支原体，存在极高的发病率，治疗方面有一些难度[1-2]。针对小儿重症支原体肺炎应用常规剂量甲强龙往往很难取得良好的应用成效，但是通过合理的加大剂量能够获得令人满意的临床效果[3]。在此背景下，我科选取了80例曾在我院接受治疗的重症支原体肺炎患儿，分别给予了不同剂量的甲强龙治疗，从而深入讨论大剂量甲强龙对其临床指标、治疗总有效率与生活质量的影响，具体报告如下：
1资料与方法
1.1 一般资料
资料来源于本院2015年2月～2017年3月收治的重症支原体肺炎患儿80例，按随机数字法将其分为实验组和对照组，每组各40例。实验组中，男22例，女18例；年龄3～8岁，平均年龄(6.1±2.5)岁；病程9～21 d，平均病程(14.3±4.2)d；体重12～28 kg，平均体重(18.2±4.1)kg。对照组中，女16例，男24例；年龄3～9岁，平均年龄(6.3±2.6)岁；病程9～22 d，平均病程(14.6±4.3)d；体重13～28 kg，平均体重(18.5±4.2)kg。实验组患儿的基本资料与对照组差异不显著(P>0.05)，可用于本次研究。, http://www.100md.com(魏众新)
参见：首页 > 医疗版 > 疾病专题 > 呼吸内科 > 肺炎 > 支原体肺炎