黛力新对原发性失眠患者睡眠脑电图的影响分析(1)
摘要：目的 分析黛力新对原发性失眠患者睡眠脑电图的影响。方法 选取2015年2月～2016年11月我院收治的原发性失眠患者114例，随机分为观察组与对照组，对照组患者给予艾司唑仑治疗，剂量为2 mg/d，观察组患者给予黛力新治疗，剂量为2片/d，对比两组患者睡眠脑电图所显示的睡眠结构、睡眠率及睡眠质量评分(PSQI)。结果 观察组患者治疗后S1、S2及REM均显著低于对照组(P<0.05)，S3、S4与对照组相比明显较高且差异有统计学意义(P<0.05)；观察组患者睡眠率与对照组相比较高(P<0.05)，PSQI评分与对照组相比显著较低(P<0.05)。结论 黛力新(氟哌噻吨美利曲辛片)对原发性失眠患者可促进睡眠结构改善，延长入睡时间，提高睡眠质量。
关键词：氟哌噻吨美利曲辛片；原发性失眠；睡眠脑电图
中图分类号：R256.23 文献标识码：A 文章编号：1006-1959(2017)21-0075-02
, 百拇医药
Analysis on Effect of Deanxit in Patients with Primary Insomnia Sleep EEG
ZHANG Bin-bin
(Department of Neurology，Dongli Hospital，Tianjin 300300，China)
Abstract：Objective To analyze the effect of Deanxit in the treatment of primary insomnia patients sleep EEG.Methods From February 2015 to November 2016 in our hospital 114 cases of primary insomnia patients，randomly divided into observation group and control group，the control group were treated with estazolam treatment，a dose of 2 mg of/d，patients in the observation group were given Deanxit treatment dose for the 2/d，the sleep structure were compared between two groups of sleep EEG shows，rate and quality of sleep score(PSQI).Results The patients in the observation group after treatment of S1，S2 and REM were significantly lower than the control group(P<0.05)，S3，S4 compared with the control group was significantly higher and the difference was statistically significant(P<0.05)；The sleep rate of the observation group was significantly higher than that of the control group (P <0.05)，and the PSQI score was significantly lower than that of the control group(P<0.05).Conclusion Deanxit(Flupentixol and Melitracen Tablets)in patients with primary insomnia can promote sleep，improve the structure，prolong the sleep time，improve the quality of sleep.
, http://www.100md.com
Key words：Flupentixol and melitracen tablets；Primary insomnia；Sleep EEG
原發性失眠主要表现为入睡困难、睡眠深度较浅、频度过短、睡眠质量差等症状，是临床常见疾病，多由忧虑、抑郁、恐惧等情绪导致，也可因压力过大引发，多发于青年或中年群体，并呈逐年上升趋势[1]。艾司唑仑是临床常用的抗原发性失眠药物，但治疗效果不理想。黛力新又称为氟哌噻吨美利曲辛片，为特异性神经阻滞剂，可有效调节中枢神经功能，主要用于改善中度心理疾患，是治疗神经衰弱、失眠、抑郁等疾病的常用药物。黛力新半衰期长，抗焦虑、抑郁效果显著，临床研究表明[2]，黛力新可有效改善失眠症状。本研究给予原发性失眠患者黛力新治疗，结果如下文。
1资料与方法
1.1一般资料
随机从2015年2月～2016年11月我院收治的原发性失眠患者中选取114例，借助随机字母表分为观察组与对照组各57例。观察组男36例，女21例，年龄25～68岁，平均年龄(47.25±6.88)岁；病程5个月～4年，平均病程(2.15±0.47)年。对照组男39例，女18例，年龄28～67岁，平均年龄(48.71±6.29)岁；病程6个月～3年，平均病程(2.01±0.39)年。纳入标准：①符合原发性失眠诊断标准；②入选前3 w内未服用抗焦虑药物、抑郁药物或安定类药物；③入选前3个月未服用损伤肝肾功能类药物。排除标准：①失眠由手术、疼痛等因素导致；②合并造血系统疾病、内分泌系统疾病、意识功能障碍；③处于妊娠期或哺乳期女性患者；④有药物滥用或依赖史。两组患者一般资料相比无明显差异(P>0.05)。, http://www.100md.com(张彬彬)
关键词：氟哌噻吨美利曲辛片；原发性失眠；睡眠脑电图
中图分类号：R256.23 文献标识码：A 文章编号：1006-1959(2017)21-0075-02
, 百拇医药
Analysis on Effect of Deanxit in Patients with Primary Insomnia Sleep EEG
ZHANG Bin-bin
(Department of Neurology，Dongli Hospital，Tianjin 300300，China)
Abstract：Objective To analyze the effect of Deanxit in the treatment of primary insomnia patients sleep EEG.Methods From February 2015 to November 2016 in our hospital 114 cases of primary insomnia patients，randomly divided into observation group and control group，the control group were treated with estazolam treatment，a dose of 2 mg of/d，patients in the observation group were given Deanxit treatment dose for the 2/d，the sleep structure were compared between two groups of sleep EEG shows，rate and quality of sleep score(PSQI).Results The patients in the observation group after treatment of S1，S2 and REM were significantly lower than the control group(P<0.05)，S3，S4 compared with the control group was significantly higher and the difference was statistically significant(P<0.05)；The sleep rate of the observation group was significantly higher than that of the control group (P <0.05)，and the PSQI score was significantly lower than that of the control group(P<0.05).Conclusion Deanxit(Flupentixol and Melitracen Tablets)in patients with primary insomnia can promote sleep，improve the structure，prolong the sleep time，improve the quality of sleep.
, http://www.100md.com
Key words：Flupentixol and melitracen tablets；Primary insomnia；Sleep EEG
原發性失眠主要表现为入睡困难、睡眠深度较浅、频度过短、睡眠质量差等症状，是临床常见疾病，多由忧虑、抑郁、恐惧等情绪导致，也可因压力过大引发，多发于青年或中年群体，并呈逐年上升趋势[1]。艾司唑仑是临床常用的抗原发性失眠药物，但治疗效果不理想。黛力新又称为氟哌噻吨美利曲辛片，为特异性神经阻滞剂，可有效调节中枢神经功能，主要用于改善中度心理疾患，是治疗神经衰弱、失眠、抑郁等疾病的常用药物。黛力新半衰期长，抗焦虑、抑郁效果显著，临床研究表明[2]，黛力新可有效改善失眠症状。本研究给予原发性失眠患者黛力新治疗，结果如下文。
1资料与方法
1.1一般资料
随机从2015年2月～2016年11月我院收治的原发性失眠患者中选取114例，借助随机字母表分为观察组与对照组各57例。观察组男36例，女21例，年龄25～68岁，平均年龄(47.25±6.88)岁；病程5个月～4年，平均病程(2.15±0.47)年。对照组男39例，女18例，年龄28～67岁，平均年龄(48.71±6.29)岁；病程6个月～3年，平均病程(2.01±0.39)年。纳入标准：①符合原发性失眠诊断标准；②入选前3 w内未服用抗焦虑药物、抑郁药物或安定类药物；③入选前3个月未服用损伤肝肾功能类药物。排除标准：①失眠由手术、疼痛等因素导致；②合并造血系统疾病、内分泌系统疾病、意识功能障碍；③处于妊娠期或哺乳期女性患者；④有药物滥用或依赖史。两组患者一般资料相比无明显差异(P>0.05)。, http://www.100md.com(张彬彬)
参见：首页 > 保健版 > 家庭健康 > 失眠睡眠 > 健康睡眠