摘要：肺损伤的机制一般认为是以血管为中心的，以PMN、巨噬细胞等反应为主的炎症过程。近年来，肺组织的氧化应激导致肺损伤备受国内外研究者的关注。

    关键词：肺损伤；肺保护；氧化应激；AOPs；氧化凋亡；炎症反应；ROS；依达拉奉；α1-AT；MMP-9

    中图分类号：R473.6 文献标识码：A 文章编号：1006-1959(2017)22-0021-03

    Abstract：The mechanism of lung injury is generally believed to be vascular centric，with PMN，macrophages and other reactions as the main inflammatory process.In recent years，lung injury caused by oxidative stress in lung tissue has attracted the attention of researchers at home and abroad.

    Key words：Lung injury；Lung protection；Oxidative stress；AOPs；Oxidative apoptosis；Inflammatory response；ROS；Edaravone；α1-AT；MMP-9

    单肺通气(OLV)[1]导致肺损伤认为是手术侧肺萎馅发生缺氧性肺血管收缩(HPV) ......