喀什地区维吾尔族非酒精性单纯性脂肪肝患者肝功及血糖、血脂代谢情况分析(1)
摘要:目的 分析喀什地区维吾尔族非酒精性单纯性脂肪肝( NAFL) 患者肝功及血糖、血脂代谢情况。方法 选取2015年5月~2016年5月就诊于喀什市人民医院的56例维吾尔族NAFL患者,对其肝功、血糖、血脂进行检测,并与本院同期接受体检的56例维吾尔族健康人群进行对比。结果 肝功能:NAFL组较健康对照组谷丙转氨酶(ALT)、谷草转氨酶(AST)、谷氨酰转肽酶(GGT)均增高(P<0.05),血脂、血糖:NAFL组高密度脂蛋白胆固醇(HDL-C)均低于健康对照组,甘油三酯(TG)、 总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、FBG(空腹血糖)均高于健康对照组(P<0.05)。结论 喀什地区维吾尔族NAFL患者存在肝功能受损、血糖及血脂代谢紊乱,对其肝功、血糖、血脂的监测有助于疾病的诊治。
关键词:非酒精性单纯性脂肪肝;肝功;血糖;血脂
中图分类号:R575.5 文献标识码:A 文章编号:1006-1959(2017)23-0061-02
, 百拇医药
Analysis of Liver Function,Blood Glucose and Blood Lipid Metabolism in Uygur Nonalcoholic Simple Fatty Liver in Kashi Area
Nurbiya·gupur1,JI Wen-jing2
(1.Department of Internal Medicine,Kashi People's Hospital,Kashi 844000,Xinjiang,China;
2.Department of Gastroenterology,the Second Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,Xinjiang,China)
, 百拇医药 Abstract:Objective To analyze the Kashi Uygur nonalcoholic fatty liver disease(NAFL)patients with liver function and blood glucose and lipid metabolism.Methods From May 2015~2016 year in May admitted to the 56 cases of Uygur NAFL patients in Kashi City People's Hospital,the liver function,blood glucose,blood lipid were detected and compared with 56 cases of Uygur healthy people in our hospital accepted medical examination at the same period.Results Liver function:NAFL group than in the healthy control group of alanine aminotransferase(ALT),aspartate aminotransferase (AST),glutamyl transpeptidase(GGT)were increased(P<0.05),Blood lipid,blood glucose:In group NAFL high density lipoprotein cholesterol(HDL-C)were lower than the healthy control group,triglyceride(TG),total cholesterol(TC),low density lipoprotein cholesterol(LDL-C),FBG(fasting blood glucose)were higher than those in healthy control group(P<0.05).Conclusion In the Kashi area,the patients with NAFL have impaired liver function,blood glucose and dyslipidemia.The monitoring of liver function,blood glucose and blood lipid is helpful to the diagnosis and treatment of disease.
, 百拇医药
Key words:Nonalcoholic fatty liver disease;Liver function;Blood glucose;Blood lipid
非酒精性脂肪性肝病(NAFLD)是一種遗传-环境-代谢应激相关性肝脏脂肪性病理变化,包括非酒精性单纯性脂肪肝(NAFL)、非酒精性脂肪性肝炎(NASH)及其相关肝纤维化、肝硬化、肝癌[1-2]。随着我国病毒性肝炎的有效防治,NAFLD已成为越来越重要的慢性肝病问题,并成为肝硬化和肝癌的重要病因[3]。本文选取2015年5月~2016年5月就诊于喀什市人民医院的56例维吾尔族NAFL患者,对其肝功、血糖、血脂进行检测,分析喀什地区维吾尔族非酒精性单纯性脂肪肝(NAFL)患者肝功及血糖、血脂代谢情况。
1 资料与方法
1.1一般资料
选取2015年5月~2016年5月就诊于喀什市人民医院的56例维吾尔族NAFL患者为观察组,其中男 32 例、女24例,年龄30~75岁,平均年龄(48.5±2.1)岁;选取同期来院进行体检的56例维吾尔族健康人群为对照组,其中男30例、女26例,年龄28~76岁,平均年龄(46.3±3.4)岁;两组一般资料差异无统计学意义(P>0.05), 具有可比性。纳入标准:无饮酒史或饮酒折合乙醇量男性每周<140 g,女性每周<70 g;符合弥漫性脂肪肝的影像学诊断标准或符合脂肪性肝病的病理学诊断标准。排除标准:排除病毒性肝炎、酒精性肝病、药物性肝病、自身免疫性肝病、肝豆状核变性及其他可致脂肪肝的特殊病例,排除合并其他严重疾病患者。, 百拇医药(努尔比亚·吾甫尔 纪文静)
关键词:非酒精性单纯性脂肪肝;肝功;血糖;血脂
中图分类号:R575.5 文献标识码:A 文章编号:1006-1959(2017)23-0061-02
, 百拇医药
Analysis of Liver Function,Blood Glucose and Blood Lipid Metabolism in Uygur Nonalcoholic Simple Fatty Liver in Kashi Area
Nurbiya·gupur1,JI Wen-jing2
(1.Department of Internal Medicine,Kashi People's Hospital,Kashi 844000,Xinjiang,China;
2.Department of Gastroenterology,the Second Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,Xinjiang,China)
, 百拇医药 Abstract:Objective To analyze the Kashi Uygur nonalcoholic fatty liver disease(NAFL)patients with liver function and blood glucose and lipid metabolism.Methods From May 2015~2016 year in May admitted to the 56 cases of Uygur NAFL patients in Kashi City People's Hospital,the liver function,blood glucose,blood lipid were detected and compared with 56 cases of Uygur healthy people in our hospital accepted medical examination at the same period.Results Liver function:NAFL group than in the healthy control group of alanine aminotransferase(ALT),aspartate aminotransferase (AST),glutamyl transpeptidase(GGT)were increased(P<0.05),Blood lipid,blood glucose:In group NAFL high density lipoprotein cholesterol(HDL-C)were lower than the healthy control group,triglyceride(TG),total cholesterol(TC),low density lipoprotein cholesterol(LDL-C),FBG(fasting blood glucose)were higher than those in healthy control group(P<0.05).Conclusion In the Kashi area,the patients with NAFL have impaired liver function,blood glucose and dyslipidemia.The monitoring of liver function,blood glucose and blood lipid is helpful to the diagnosis and treatment of disease.
, 百拇医药
Key words:Nonalcoholic fatty liver disease;Liver function;Blood glucose;Blood lipid
非酒精性脂肪性肝病(NAFLD)是一種遗传-环境-代谢应激相关性肝脏脂肪性病理变化,包括非酒精性单纯性脂肪肝(NAFL)、非酒精性脂肪性肝炎(NASH)及其相关肝纤维化、肝硬化、肝癌[1-2]。随着我国病毒性肝炎的有效防治,NAFLD已成为越来越重要的慢性肝病问题,并成为肝硬化和肝癌的重要病因[3]。本文选取2015年5月~2016年5月就诊于喀什市人民医院的56例维吾尔族NAFL患者,对其肝功、血糖、血脂进行检测,分析喀什地区维吾尔族非酒精性单纯性脂肪肝(NAFL)患者肝功及血糖、血脂代谢情况。
1 资料与方法
1.1一般资料
选取2015年5月~2016年5月就诊于喀什市人民医院的56例维吾尔族NAFL患者为观察组,其中男 32 例、女24例,年龄30~75岁,平均年龄(48.5±2.1)岁;选取同期来院进行体检的56例维吾尔族健康人群为对照组,其中男30例、女26例,年龄28~76岁,平均年龄(46.3±3.4)岁;两组一般资料差异无统计学意义(P>0.05), 具有可比性。纳入标准:无饮酒史或饮酒折合乙醇量男性每周<140 g,女性每周<70 g;符合弥漫性脂肪肝的影像学诊断标准或符合脂肪性肝病的病理学诊断标准。排除标准:排除病毒性肝炎、酒精性肝病、药物性肝病、自身免疫性肝病、肝豆状核变性及其他可致脂肪肝的特殊病例,排除合并其他严重疾病患者。, 百拇医药(努尔比亚·吾甫尔 纪文静)
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