促排卵方案治疗多囊卵巢综合征不孕的应用及价值评定(1)

http://www.100md.com 2017年6月11日 医学信息 2017年第23期

     摘要：目的 研究促排卵方案治疗多囊卵巢综合征不孕的应用及价值。方法 以我院2015年5月～2016年6月多囊卵巢综合征不孕患者100例随机分两组。传统组采用传统克罗米芬进行治疗，联合组在传统组基础上加上人绝经期促性腺激素。比较两组患者临床妊娠率、卵巢过度刺激综合征发生率；优势卵泡直径、成熟卵泡数。结果 联合组患者临床妊娠率高于传统组，P<0.05；联合组卵巢过度刺激综合征发生率跟传统组无显著差异，P>0.05；联合组优势卵泡直径跟传统组无显著差异，P>0.05；联合组成熟卵泡数多于传统组，P<0.05。结论 克罗米芬+人绝经期促性腺激素促排卵方案治疗多囊卵巢综合征不孕的应用及价值高，可有效提高妊娠率，增加成熟卵泡数，且不增加卵巢过度刺激综合征发生率，安全有效，值得推广。

    关键词：促排卵方案；多囊卵巢综合征不孕；成熟卵泡；人绝经期促性腺激素

    中图分类号：R711.75 文献标识码：A 文章编号：1006-1959(2017)23-0084-02
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    Application and Value Evaluation of Ovulation Induction Therapy in Infertile Women with Polycystic Ovary Syndrome

    ZENG Yi，LI Yan-mei，LAI Guo-qing，LUO Jia-fang

    (Department of Obstetrics and Gynecology，Third Affiliated Hospital of Gannan Medical College，Ganzhou 341000，Jiangxi，China)

    Abstract：Objective To study the application and value of ovulation induction therapy for infertility of polycystic ovary syndrome.Methods From May 2015 to June 2016，100 patients with polycystic ovary syndrome were randomly divided into two groups.The traditional group was treated with traditional clomiphene，and the combined group was supplemented with human menopausal gonadotropin on the basis of the traditional group. Comparison of the two groups of patients with clinical pregnancy rate，the incidence of ovarian hyperstimulation syndrome；dominant follicular diameter， the number of mature follicles.Results The clinical pregnancy rate of the combined group was higher than that of the traditional group，P<0.05；The incidence of ovarian hyperstimulation syndrome in the combined group was not significantly different from that in the traditional group，P> 0.05，There was no significant difference in the follicle diameter between the combined group and the traditional group，P>0.05，The number of mature follicles in the combined group was higher than that in the traditional group，P<0.05.Conclusion The application and high value of clomiphene+menopausal gonadotropin-induced ovulation regimen in the treatment of infertility with polycystic ovary syndrome can improve the pregnancy rate and increase the number of mature follicles without increasing the incidence of ovarian hyperstimulation syndrome，effective，worthy of promotion.
, 百拇医药
    Key words：Ovulation program；Polycystic ovary syndrome infertility；Mature follicles；Human menopausal gonadotropin

    多囊卵巢綜合征不孕为育龄女性常见不孕原因，在内分泌性不孕中占比较高。临床对多囊卵巢综合征不孕患者的治疗多采取促排卵治疗，传统多给予克罗米芬进行促排卵，但受孕率比较低[1]。我们加入了人绝经期促性腺激素，对促排卵方案治疗多囊卵巢综合征不孕的应用及价值进行分析，报告如下。

    1资料与方法

    1.1一般资料

    以我院2015年5月～2016年6月多囊卵巢综合征不孕患者100例随机分两组。所有患者符合多囊卵巢综合征不孕诊断标准，均知情同意本次研究。联合组患者23～40岁，平均年龄(29.34±2.45)岁。不孕时间1～11年，平均时间(3.51±0.29)年。传统组患者21～40岁，平均年龄(29.68±2.41)岁。不孕时间1～11年，平均时间(3.53±0.25)年。两组一般资料差异不显著，P>0.05，本次研究已通过医学伦理委员会审批同意。, 百拇医药(曾夷 李艳梅 赖国清 罗家芳)

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