氨溴索注射液、异丙托溴铵、布地奈德混悬液联合治疗小儿支气管肺炎的临床观察(1)
摘要：目的 研究氨溴索注射液、异丙托溴铵、布地奈德混悬液联合雾化吸入治疗小儿支气管肺炎的临床疗效。方法 选取2014年1月～2016年12月于我院就诊的支气管肺炎患儿98例，采用随机数字表法，均分为观察组与对照组各49例，对照组患儿给予常规治疗，观察组患儿在此基础上给予氨溴索注射液、异丙托溴铵、布地奈德混悬液联合雾化吸入治疗，对比两组患儿的治疗效果。结果 观察组患儿的治疗总有效率显著高于对照组(P<0.05)；观察组患儿的发热、气促、憋喘、咳嗽、肺部X射线消失/缓解/恢复时间均显著短于对照组(P<0.05)；观察组患儿治疗后的CRP、IL-6、TNF-α、WBC均显著低于对照组(P<0.05)。结论 氨溴索注射液、异丙托溴铵、布地奈德混悬液联合雾化吸入治疗能够有效改善支气管肺炎患儿的临床症状，临床疗效显著，具有推广使用价值。
关键词：小儿支气管肺炎；氨溴索注射液；异丙托溴铵；布地奈德混悬液
中图分类号：R725.6 文献标识码：A 文章编号：1006-1959(2017)24-0079-03
, http://www.100md.com
Clinical Observation of Combination of Ambroxol Injection，Ipratropium Bromide and Budesonide Suspension in Children with Bronchial Pneumonia
WU Yun-duo，LIN Xiao-fei，HUA Wei
(Department of Pediatrics，Huai'an Maternal and Child Health Hospital，Huai'an 223000，Jiangsu，China)
Abstract：Objective To study the clinical efficacy of ambroxol injection，ipratropium bromide，budesonide suspension combined with aerosol inhalation in children with bronchial pneumonia.Methods 98 cases of bronchial pneumonia from January 2014～2016 year in December in our hospital，were randomly divided into observation group and control group with 49 cases in each group，the control group were given conventional treatment， observation group were given ambroxol hydrochloride injection，ipratropium bromide and Budesonide aerosol inhalation treatment of the two groups were compared.Results The therapeutic effect of treatment in the observation group the total effective rate was significantly higher than that of the control group(P<0.05)；observation group of children with fever，shortness of breath，dyspnea，cough，lung X ray disappeared/response/recovery time were significantly shorter than the control group(P<0.05)；the treatment in the observation group after CRP，IL-6，TNF-α，WBC were significantly lower than the control group(P<0.05).Conclusion Ambroxol，ipratropium bromide and budesonide inhalation therapy can effectively improve the clinical symptoms in children with bronchial pneumonia，the clinical curative effect is remarkable，and it has popularization and application value.
, 百拇医药
Key words：Children bronchial pneumonia；Ambroxol injection；Ipratropium bromide；Budesonide suspension
小兒支气管肺炎是婴幼儿时期常见的呼吸系统疾病，是婴儿时期死亡的主要原因，临床症状主要表现为咳嗽、发热、气促、呼吸困难、肺部固定细湿啰音等，且病情迁延难以治愈，容易发生心、脑、肠胃道损害，严重威胁着患儿的生命安全[1]。因此，本文采用氨溴索注射液、异丙托溴铵、布地奈德混悬液联合雾化吸入治疗小儿支气管肺炎，治疗效果满意，现报告如下。
1资料与方法
1.1一般资料
选取2014年1月～2016年12月于我院就诊的支气管肺炎患儿98例，所有患儿均经过检查符合第七版《诸福棠实用儿科学》中关于小儿支气管肺炎的诊断标准[2]；排除重症肺炎、合并心肝肾疾病、精神疾病、造血系统疾病等患者；采用随机数字表法，将患者均分为观察组与对照组各49例；观察组：男26例，女23例，年龄3～12岁，平均年龄(5.67±1.38)岁，病程3～41 d，平均病程(26.45±3.88)d；对照组男27例，女22例，年龄3～12岁，平均年龄(5.61±1.42)岁，病程4～42d，平均病程(27.13±3.96)d；两组患儿在性别、年龄、病程等一般资料方面对比差异不显著，无统计学意义，两组具有可比性(P>0.05)。, http://www.100md.com(吴云朵 林小飞 华伟)
关键词：小儿支气管肺炎；氨溴索注射液；异丙托溴铵；布地奈德混悬液
中图分类号：R725.6 文献标识码：A 文章编号：1006-1959(2017)24-0079-03
, http://www.100md.com
Clinical Observation of Combination of Ambroxol Injection，Ipratropium Bromide and Budesonide Suspension in Children with Bronchial Pneumonia
WU Yun-duo，LIN Xiao-fei，HUA Wei
(Department of Pediatrics，Huai'an Maternal and Child Health Hospital，Huai'an 223000，Jiangsu，China)
Abstract：Objective To study the clinical efficacy of ambroxol injection，ipratropium bromide，budesonide suspension combined with aerosol inhalation in children with bronchial pneumonia.Methods 98 cases of bronchial pneumonia from January 2014～2016 year in December in our hospital，were randomly divided into observation group and control group with 49 cases in each group，the control group were given conventional treatment， observation group were given ambroxol hydrochloride injection，ipratropium bromide and Budesonide aerosol inhalation treatment of the two groups were compared.Results The therapeutic effect of treatment in the observation group the total effective rate was significantly higher than that of the control group(P<0.05)；observation group of children with fever，shortness of breath，dyspnea，cough，lung X ray disappeared/response/recovery time were significantly shorter than the control group(P<0.05)；the treatment in the observation group after CRP，IL-6，TNF-α，WBC were significantly lower than the control group(P<0.05).Conclusion Ambroxol，ipratropium bromide and budesonide inhalation therapy can effectively improve the clinical symptoms in children with bronchial pneumonia，the clinical curative effect is remarkable，and it has popularization and application value.
, 百拇医药
Key words：Children bronchial pneumonia；Ambroxol injection；Ipratropium bromide；Budesonide suspension
小兒支气管肺炎是婴幼儿时期常见的呼吸系统疾病，是婴儿时期死亡的主要原因，临床症状主要表现为咳嗽、发热、气促、呼吸困难、肺部固定细湿啰音等，且病情迁延难以治愈，容易发生心、脑、肠胃道损害，严重威胁着患儿的生命安全[1]。因此，本文采用氨溴索注射液、异丙托溴铵、布地奈德混悬液联合雾化吸入治疗小儿支气管肺炎，治疗效果满意，现报告如下。
1资料与方法
1.1一般资料
选取2014年1月～2016年12月于我院就诊的支气管肺炎患儿98例，所有患儿均经过检查符合第七版《诸福棠实用儿科学》中关于小儿支气管肺炎的诊断标准[2]；排除重症肺炎、合并心肝肾疾病、精神疾病、造血系统疾病等患者；采用随机数字表法，将患者均分为观察组与对照组各49例；观察组：男26例，女23例，年龄3～12岁，平均年龄(5.67±1.38)岁，病程3～41 d，平均病程(26.45±3.88)d；对照组男27例，女22例，年龄3～12岁，平均年龄(5.61±1.42)岁，病程4～42d，平均病程(27.13±3.96)d；两组患儿在性别、年龄、病程等一般资料方面对比差异不显著，无统计学意义，两组具有可比性(P>0.05)。, http://www.100md.com(吴云朵 林小飞 华伟)
参见：首页 > 医疗版 > 疾病专题 > 呼吸内科 > 肺炎