不同血液净化方式对维持性血液透析患者残余肾功能影响的临床护理观察(1)
摘 要:目的 应用两种血液净化方法对患者进行维持性血液透析治疗,探析这两种方式对患者残余肾功能的影响。方法 选择我科收治的120例行常规血液透析的尿毒症患者,对照组采用低通量血液透析方式治疗,观察组采用血液透析联合血液灌流(HD+HP)方式治疗,对比两组患者治疗前后RRF等相关指标。结果 治疗前两组各项指标无明显差异(P>0.05),治疗前后观察组患者的RRF、总胆固醇等指标变化明显,与对照组相比差异显著(P<0.05)。结论 HD+HP方式治疗维持性血液透析患者,可有效保护患者残余肾功能,多项指标均明显降低,值得推广应用。
关键词:维持性血液透析;血液净化;残余肾功能;护理
中图分类号:R473.5 文献标识码:A DOI:10.3969/j.issn.1006-1959.2018.01.066
文章编号:1006-1959(2018)01-0167-02
, 百拇医药
Clinical Nursing Observation on the Influence of Different Blood Purification Methods on Residual Renal Function in Maintenance Hemodialysis Patients
QI Ya-xuan
(Department of Dialysis,Jizhou District People's Hospital,Tianjin 301900,China)
Abstract:Objective To apply two kinds of blood purification methods to patients for maintenance hemodialysis treatment and to explore the influence of these two methods on residual renal function in patients.Methods A total of 120 uremic patients undergoing routine hemodialysis were enrolled in this study.The control group was treated by low-flux hemodialysis.The observation group was treated by hemodialysis combined with hemoperfusion(HD+HP).Before and after treatment RRF and other related indicators.Results There was no significant difference between the two groups before treatment(P>0.05).RRF and total cholesterol in the observation group changed significantly before and after treatment,with significant difference compared with the control group(P<0.05).Conclusion HD+HP treatment of patients with maintenance hemodialysis can effectively protect the residual renal function,a number of indicators were significantly reduced,it is worth promoting the application.
, 百拇医药
Key words:Maintenance hemodialysis;Blood purification;Residual renal function;Nursing
殘余肾功能(Residual renal function,RRF)是指患者肾脏损伤之后残存实质部分内分泌与滤过功能,对于维持性血液透析患者清除体内毒素意义重大[1]。临床资料显示[2],残余肾功能的功能很多,可以明显改善患者钙磷代谢紊乱问题,也会对膳食蛋白摄入、维持营养情况等方面起到明显作用。本次研究主要对比两种血液净化方式对患者残余肾功能的影响,现在进行如下分析。
1资料与方法
1.1一般资料 选取我院2015年1月~2017年1月收治的120例行常规血液透析的尿毒症患者,行透析治疗2个月以上,原发病慢性肾小球肾炎49例,糖尿病肾病有31例,高血压肾病28例,其他12例。按照随机数字表法将患者分为对照组和观察组各60例。对照组男33例,女27例,年龄27~66岁,平均年龄(46.31±5.40)岁;观察组男34例,女26例,年龄28~65岁,平均年龄(47.21±5.72)岁。两组基本资料差异无统计学意义(P>0.05),可比较。
, 百拇医药
1.2方法 对照组选用低通量血液透析方式,3次/w,每次治疗持续4 h。观察组为血液透析联合血液灌流(HD+HP),3次/w,每次治疗持续4 h,每周第1次透析即与HA130血液灌流器串联,治疗2 h后将血液灌流器撤下,持续HD治疗2 h后结束。两组患者的血液持续治疗均用到了聚砜膜透析器F6、透析机及碳酸氢钠透析液,普通肝素抗凝,透析过程中将血液速度和透析液流速分别调节至250 ml/min、500 ml/min。
1.3观察指标 分别于治疗前、治疗后6个月采集血尿标本,并检测两组患者的总胆固醇等相关指标,计算RRF。
1.4统计学方法 采用SPSS19.0统计学软件处理数据,计量资料用(x±s)表示,计数资料用(%)表示,χ2检验。P<0.05为两组患者数据统计具有差异。, 百拇医药(祁亚轩)
关键词:维持性血液透析;血液净化;残余肾功能;护理
中图分类号:R473.5 文献标识码:A DOI:10.3969/j.issn.1006-1959.2018.01.066
文章编号:1006-1959(2018)01-0167-02
, 百拇医药
Clinical Nursing Observation on the Influence of Different Blood Purification Methods on Residual Renal Function in Maintenance Hemodialysis Patients
QI Ya-xuan
(Department of Dialysis,Jizhou District People's Hospital,Tianjin 301900,China)
Abstract:Objective To apply two kinds of blood purification methods to patients for maintenance hemodialysis treatment and to explore the influence of these two methods on residual renal function in patients.Methods A total of 120 uremic patients undergoing routine hemodialysis were enrolled in this study.The control group was treated by low-flux hemodialysis.The observation group was treated by hemodialysis combined with hemoperfusion(HD+HP).Before and after treatment RRF and other related indicators.Results There was no significant difference between the two groups before treatment(P>0.05).RRF and total cholesterol in the observation group changed significantly before and after treatment,with significant difference compared with the control group(P<0.05).Conclusion HD+HP treatment of patients with maintenance hemodialysis can effectively protect the residual renal function,a number of indicators were significantly reduced,it is worth promoting the application.
, 百拇医药
Key words:Maintenance hemodialysis;Blood purification;Residual renal function;Nursing
殘余肾功能(Residual renal function,RRF)是指患者肾脏损伤之后残存实质部分内分泌与滤过功能,对于维持性血液透析患者清除体内毒素意义重大[1]。临床资料显示[2],残余肾功能的功能很多,可以明显改善患者钙磷代谢紊乱问题,也会对膳食蛋白摄入、维持营养情况等方面起到明显作用。本次研究主要对比两种血液净化方式对患者残余肾功能的影响,现在进行如下分析。
1资料与方法
1.1一般资料 选取我院2015年1月~2017年1月收治的120例行常规血液透析的尿毒症患者,行透析治疗2个月以上,原发病慢性肾小球肾炎49例,糖尿病肾病有31例,高血压肾病28例,其他12例。按照随机数字表法将患者分为对照组和观察组各60例。对照组男33例,女27例,年龄27~66岁,平均年龄(46.31±5.40)岁;观察组男34例,女26例,年龄28~65岁,平均年龄(47.21±5.72)岁。两组基本资料差异无统计学意义(P>0.05),可比较。
, 百拇医药
1.2方法 对照组选用低通量血液透析方式,3次/w,每次治疗持续4 h。观察组为血液透析联合血液灌流(HD+HP),3次/w,每次治疗持续4 h,每周第1次透析即与HA130血液灌流器串联,治疗2 h后将血液灌流器撤下,持续HD治疗2 h后结束。两组患者的血液持续治疗均用到了聚砜膜透析器F6、透析机及碳酸氢钠透析液,普通肝素抗凝,透析过程中将血液速度和透析液流速分别调节至250 ml/min、500 ml/min。
1.3观察指标 分别于治疗前、治疗后6个月采集血尿标本,并检测两组患者的总胆固醇等相关指标,计算RRF。
1.4统计学方法 采用SPSS19.0统计学软件处理数据,计量资料用(x±s)表示,计数资料用(%)表示,χ2检验。P<0.05为两组患者数据统计具有差异。, 百拇医药(祁亚轩)