非小细胞肺癌中ZEB1和FoxO3a表达及意义(4)
[5]Liu H，Yin J，Wang H，et al.FOXO3a modulates WNT β-catenin signaling and suppresses epithelial-to-mesenchymal transition in prostate cancer cells[J].Cellular Signalling，2015，27(3)：510.
[6]Travis WD，Brambilla E，Mqller-Hermelink HK，et al.World Health Organization classification of tumours.Pathologyand genetics of tumours of the lung，pleura，thymus and heart[M].4th，Lyon：IARC Press；2015.
[7]Rami-Porta R，Bolejack V，Crowley J，et al.The IASLC Lung Cancer Staging Project Proposals for the Revisions of the T Descriptors in the Forthcoming Eighth Edition of the TNM Classification for Lung Cancer[J]. J Thorac Oncol，2015，10(7)：990-1003.
, http://www.100md.com
[8]Y Zhang，L You，J chen，et al.Expression of kinesin family member 3B is associated with poor prognosis in epithelial ovarian cancer patients[J].Int J Clin Exp Pathol，2017，10(3)：2834-2842.
[9]Guan H，Liang W，Xie Z，et al.Down-regulation of miR-144 promotes thyroid cancer cell invasion by targeting ZEB1 and ZEB2[J].Endocrine，2015，48(2)：566-574.
[10]Niu K，Shen W，Zhang Y，et al.MiR-205 promotes motility of ovarian cancer cells via targeting ZEB1[J].Gene，2015，574(2)：330-336.
, 百拇医药
[11]Larsen J E，Nathan V，Osborne J K，et al.ZEB1 drives epithelial-to-mesenchymal transition in lung cancer[J].Journal of Clinical Investigation，2016，126(9)：3219.
[12]仲楼，史加海，曹飞，等.ZEB1的表达与肺鳞状细胞癌侵袭及转移的关系[J].吉林大学学报(医学版)，2012，38(4)：761-765.
[13]Coopman P，Djiane A.Adherens Junction and E-Cadherin complex regulation by epithelial polarity[J].Journal of Marine Systems，2016，73(18)：3535-3553.
[14]Cappellesso R，Marioni G，Crescenzi M，et al.The prognostic role of the Epithelial-Mesenchymal Transition markers E-cadherin and Slug in laryngeal squamous cell carcinoma[J].Histopathology，2015，67(4)：491-500.
, 百拇医药
[15]Ni D，Ma X，Li H Z，et al.Downregulation of FOXO3a promotes tumor metastasis and is associated with metastasis-free survival of patients with clear cell renal cell carcinoma[J].Clinical Cancer Research An Official Journal of the American Association for Cancer Research，2014，20(7)：1779-1790.
[16]Belguise K，Guo S，Sonenshein G E.Activation of FOXO3a by the Green Tea Polyphenol Epigallocatechin-3-Gallate Induces Estrogen Receptor Expression Reversing Invasive Phenotype of Breast Cancer Cells[J].Cancer Research，2007，67(12)：5763.
, 百拇医药
[17]Cheng CW，Chen PM，Hsieh YH，et al.Foxo3a-mediated overexpression of microRNA-622 suppresses tumor metastasis by repressing hypoxia-inducible factor-1α in ERK-responsive lung cancer[J].Oncotarget，2015，6(42)：44222.
[18]Zhang L，Zhang W，Li Y，et al.SHP-2-upregulated ZEB1 is important for PDGFRα-driven glioma epithelial-mesenchymal transition and invasion in mice and humans[J].Oncogene，2016， 35(43)：5641-5652.
[19]Wu K，Fan J，Zhang L，et al.PI3K Akt to GSK3β β-catenin signaling cascade coordinates cell colonization for bladder cancer bone metastasis through regulating ZEB1 transcription[J].Cellular Signalling，2012，24(12)：2273-2282.
, 百拇医药
[20]Zhou G，Zhang F，Guo Y，et al.miR-200c enhances sensitivity of drug-resistant non-small cell lung cancer to gefitinib by suppression of PI3K Akt signaling pathway and inhibites cell migration via targeting ZEB1[J].Biomedicine&Pharmacotherapy，2017，85(11)：113-119.
收稿日期：2017-11-10；修回日期：2017-11-13
編辑/李桦, 百拇医药(田亮 郭楠 苗志刚 郭效忠 张楠 彭宁宁 苗玉 张荣菊)
[6]Travis WD，Brambilla E，Mqller-Hermelink HK，et al.World Health Organization classification of tumours.Pathologyand genetics of tumours of the lung，pleura，thymus and heart[M].4th，Lyon：IARC Press；2015.
[7]Rami-Porta R，Bolejack V，Crowley J，et al.The IASLC Lung Cancer Staging Project Proposals for the Revisions of the T Descriptors in the Forthcoming Eighth Edition of the TNM Classification for Lung Cancer[J]. J Thorac Oncol，2015，10(7)：990-1003.
, http://www.100md.com
[8]Y Zhang，L You，J chen，et al.Expression of kinesin family member 3B is associated with poor prognosis in epithelial ovarian cancer patients[J].Int J Clin Exp Pathol，2017，10(3)：2834-2842.
[9]Guan H，Liang W，Xie Z，et al.Down-regulation of miR-144 promotes thyroid cancer cell invasion by targeting ZEB1 and ZEB2[J].Endocrine，2015，48(2)：566-574.
[10]Niu K，Shen W，Zhang Y，et al.MiR-205 promotes motility of ovarian cancer cells via targeting ZEB1[J].Gene，2015，574(2)：330-336.
, 百拇医药
[11]Larsen J E，Nathan V，Osborne J K，et al.ZEB1 drives epithelial-to-mesenchymal transition in lung cancer[J].Journal of Clinical Investigation，2016，126(9)：3219.
[12]仲楼，史加海，曹飞，等.ZEB1的表达与肺鳞状细胞癌侵袭及转移的关系[J].吉林大学学报(医学版)，2012，38(4)：761-765.
[13]Coopman P，Djiane A.Adherens Junction and E-Cadherin complex regulation by epithelial polarity[J].Journal of Marine Systems，2016，73(18)：3535-3553.
[14]Cappellesso R，Marioni G，Crescenzi M，et al.The prognostic role of the Epithelial-Mesenchymal Transition markers E-cadherin and Slug in laryngeal squamous cell carcinoma[J].Histopathology，2015，67(4)：491-500.
, 百拇医药
[15]Ni D，Ma X，Li H Z，et al.Downregulation of FOXO3a promotes tumor metastasis and is associated with metastasis-free survival of patients with clear cell renal cell carcinoma[J].Clinical Cancer Research An Official Journal of the American Association for Cancer Research，2014，20(7)：1779-1790.
[16]Belguise K，Guo S，Sonenshein G E.Activation of FOXO3a by the Green Tea Polyphenol Epigallocatechin-3-Gallate Induces Estrogen Receptor Expression Reversing Invasive Phenotype of Breast Cancer Cells[J].Cancer Research，2007，67(12)：5763.
, 百拇医药
[17]Cheng CW，Chen PM，Hsieh YH，et al.Foxo3a-mediated overexpression of microRNA-622 suppresses tumor metastasis by repressing hypoxia-inducible factor-1α in ERK-responsive lung cancer[J].Oncotarget，2015，6(42)：44222.
[18]Zhang L，Zhang W，Li Y，et al.SHP-2-upregulated ZEB1 is important for PDGFRα-driven glioma epithelial-mesenchymal transition and invasion in mice and humans[J].Oncogene，2016， 35(43)：5641-5652.
[19]Wu K，Fan J，Zhang L，et al.PI3K Akt to GSK3β β-catenin signaling cascade coordinates cell colonization for bladder cancer bone metastasis through regulating ZEB1 transcription[J].Cellular Signalling，2012，24(12)：2273-2282.
, 百拇医药
[20]Zhou G，Zhang F，Guo Y，et al.miR-200c enhances sensitivity of drug-resistant non-small cell lung cancer to gefitinib by suppression of PI3K Akt signaling pathway and inhibites cell migration via targeting ZEB1[J].Biomedicine&Pharmacotherapy，2017，85(11)：113-119.
收稿日期：2017-11-10；修回日期：2017-11-13
編辑/李桦, 百拇医药(田亮 郭楠 苗志刚 郭效忠 张楠 彭宁宁 苗玉 张荣菊)