等离子射频消融术治疗腺样体肥大对术中创伤程度和术后免疫功能的影响分析(1)
摘 要:目的 探究等离子射频消融术应用于腺样体肥大治疗中的临床效果。方法 选取2016年8月~2017年8月收治的92例患腺体肥大儿童资料,依治疗方式分为对照组和研究组,各46例。对照组采用传统切割吸引刀治疗,研究组采用等离子射频消融术治疗,比较两组术中创伤程度、术后免疫功能以及临床疗效。结果 研究组术中创伤程度和术后免疫指标均低于对照组,差异有统計学意义(P<0.05)。研究组治疗总有效率为91.30%,高于对照组的73.91%,差异有统计学意义(P<0.05)。结论 应用等离子射频消融术治疗腺体肥大效果明显,术中承受创伤程度小,术后机体免疫性好,减少治疗对患儿发育的影响,值得普及使用。
关键词:等离子射频消融术;腺样体肥大;创伤程度;免疫功能
中图分类号:R766.9 文献标识码:A DOI:10.3969/j.issn.1006-1959.2018.04.032
文章编号:1006-1959(2018)04-0098-02
, 百拇医药
Abstract:Objective To investigate the clinical effect of plasma radiofrequency ablation in the treatment of adenoid hypertrophy.Methods From August 2016 to August 2017,92 cases of children with hypertrophy of glands were selected.The patients were divided into control group (46 cases) and study group (46 cases) according to treatment method.The control group was treated with traditional incision suction knife,the study group was treated with plasma radiofrequency ablation.The degree of trauma,postoperative immune function and clinical effect were compared between the two groups.Results The degree of intraoperative trauma and postoperative immune indexes in the study group were lower than those in the control group,the difference was statistically significant(P<0.05).The total effective rate of treatment in the study group was 91.30%,which was higher than that of the control group 73.91%,and the difference was statistically significant(P<0.05).Conclusion Plasma radiofrequency ablation is effective in the treatment of hypertrophy in children.Postoperative immunity is good,reduce the effect of treatment on the development of children,it is worth popularizing.
, 百拇医药
Key words:Plasma radiofrequency ablation;Adenoid hypertrophy;Degree of trauma;Immune function
腺样体肥大(adenoid hypertrophy)是由于炎症反复刺激造成的腺样体病理增生,早期病灶切除是最佳治疗手段,但患儿年龄较小,手术方式的选择是临床首要思考的问题[1-2]。为提升治疗效果,本次研究选取入院治疗的92例患腺体肥大儿童,观察应用等离子射频消融术的治疗效果,现报告如下。
1资料与方法
1.1一般资料 选取2016年8月~2017年8月本院收治的92例患腺体肥大儿童,依治疗方式不同分为对照组和研究组,每组46例。对照组中,男25例,女21例,年龄3~11岁,平均年龄(6.14±1.81)岁;病程1~5年,平均病程(3.17±1.09)年。研究组中,男22例,女24例,年龄2~10岁,平均年龄(5.37±2.04)岁;病程2~4年,平均病程(2.56±1.02)年。两组基线资料相比,差异无统计学意义(P>0.05),有可比性。
, 百拇医药
1.2方法
1.2.1对照组 采用传统切割吸引刀。插管全麻,通过鼻内镜起到辅助效果,持镜直视采用电动切割器对肥大的腺样体病灶进行组织切割,压迫止血。
1.2.2研究组 采用等离子射频消融术。插管全麻,在开口器辅助下显露口咽,在鼻腔双侧至口咽各引入1根细导管,向上提升软腭固定,使鼻咽部暴露。置入鼻内镜,在监视器下对腺样体的增生情况进行观察,透过低温等离子的射频消融刀对增生肥大组织进行彻底清除。
1.3观察指标 在手术结束的即刻与术后24 h分别对患儿行外周静脉的1 ml血液采集,通过酶联吸附测试含量:①术中创伤指标:C反应蛋白(CRP)、P物质(SP)及前列腺素E2(PGE2);②术后免疫指标:免疫球蛋白A(IgA)、G(IgG)、M(IgM)以及补体C3、C4。, 百拇医药(杨磊)
关键词:等离子射频消融术;腺样体肥大;创伤程度;免疫功能
中图分类号:R766.9 文献标识码:A DOI:10.3969/j.issn.1006-1959.2018.04.032
文章编号:1006-1959(2018)04-0098-02
, 百拇医药
Abstract:Objective To investigate the clinical effect of plasma radiofrequency ablation in the treatment of adenoid hypertrophy.Methods From August 2016 to August 2017,92 cases of children with hypertrophy of glands were selected.The patients were divided into control group (46 cases) and study group (46 cases) according to treatment method.The control group was treated with traditional incision suction knife,the study group was treated with plasma radiofrequency ablation.The degree of trauma,postoperative immune function and clinical effect were compared between the two groups.Results The degree of intraoperative trauma and postoperative immune indexes in the study group were lower than those in the control group,the difference was statistically significant(P<0.05).The total effective rate of treatment in the study group was 91.30%,which was higher than that of the control group 73.91%,and the difference was statistically significant(P<0.05).Conclusion Plasma radiofrequency ablation is effective in the treatment of hypertrophy in children.Postoperative immunity is good,reduce the effect of treatment on the development of children,it is worth popularizing.
, 百拇医药
Key words:Plasma radiofrequency ablation;Adenoid hypertrophy;Degree of trauma;Immune function
腺样体肥大(adenoid hypertrophy)是由于炎症反复刺激造成的腺样体病理增生,早期病灶切除是最佳治疗手段,但患儿年龄较小,手术方式的选择是临床首要思考的问题[1-2]。为提升治疗效果,本次研究选取入院治疗的92例患腺体肥大儿童,观察应用等离子射频消融术的治疗效果,现报告如下。
1资料与方法
1.1一般资料 选取2016年8月~2017年8月本院收治的92例患腺体肥大儿童,依治疗方式不同分为对照组和研究组,每组46例。对照组中,男25例,女21例,年龄3~11岁,平均年龄(6.14±1.81)岁;病程1~5年,平均病程(3.17±1.09)年。研究组中,男22例,女24例,年龄2~10岁,平均年龄(5.37±2.04)岁;病程2~4年,平均病程(2.56±1.02)年。两组基线资料相比,差异无统计学意义(P>0.05),有可比性。
, 百拇医药
1.2方法
1.2.1对照组 采用传统切割吸引刀。插管全麻,通过鼻内镜起到辅助效果,持镜直视采用电动切割器对肥大的腺样体病灶进行组织切割,压迫止血。
1.2.2研究组 采用等离子射频消融术。插管全麻,在开口器辅助下显露口咽,在鼻腔双侧至口咽各引入1根细导管,向上提升软腭固定,使鼻咽部暴露。置入鼻内镜,在监视器下对腺样体的增生情况进行观察,透过低温等离子的射频消融刀对增生肥大组织进行彻底清除。
1.3观察指标 在手术结束的即刻与术后24 h分别对患儿行外周静脉的1 ml血液采集,通过酶联吸附测试含量:①术中创伤指标:C反应蛋白(CRP)、P物质(SP)及前列腺素E2(PGE2);②术后免疫指标:免疫球蛋白A(IgA)、G(IgG)、M(IgM)以及补体C3、C4。, 百拇医药(杨磊)