凝血酶原时间与血小板检验方式对诊断肝硬化疾病的临床价值研究(1)
摘 要：目的 研究凝血酶原时间(PT)与血小板检验方式对肝硬化疾病患者进行诊断的临床价值。方法 选取2016年5月～2017年5月在我院诊治的100例肝硬化患者作为观察组，并选取同期进行健康体检的100例健康者作为对照组，分别检测PT与血小板，对比两组血小板指标、PT，观察疾病组出血现象和无出血现象患者的血小板指标和PT。结果 观察组血小板体积(MPV)、血小板分布宽度(PDW)明显高于对照组，血小板计数(PLT)、血小板压积(PCT)明显低于对照组，差异有统计学意义(P<0.05)；观察组PT明显高于对照组，差异有统计学意义(P<0.05)；无出血患者PCT、PLT明显低于出血患者，MPV、PDW、PT明显高于出血患者，差异有统计学意义(P<0.05)。结论 凝血酶原时间和血小板检验与肝硬化患者病情发展有直接的关系，且随着病情的加重，会发生相应的改变，对临床诊断肝硬化具有重要的临床价值。
关键词：凝血酶原时间；血小板检验；肝硬化；临床价值
中图分类号：R575.2 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.04.055
, http://www.100md.com
文章编号：1006-1959(2018)04-0150-02
Abstract：Objective To study the diagnostic value of prothrombin time(PT)and platelet test in patients with liver cirrhosis.Methods From May 2016 to May2017 in 100 patients with liver cirrhosis in our hospital as the observation group，and selected 100 healthy cases were concurrent healthy as control group，PT and platelet were detected，compared two groups of platelet index，PT，observation of disease group bleeding and non bleeding phenomenon of blood platelet index and PT.Results In the observation group，platelet volume(MPV)，platelet distribution width(PDW)were significantly higher than the control group，the platelet count(PLT)，plateletcrit (PCT) was significantly lower than the control group，the difference was statistically significant(P<0.05)；the observation group PT was significantly higher than the control group，the difference was statistically significant(P<0.05)no bleeding；patients with PCT，PLT was significantly lower than that of MPV，PDW，hemorrhage，PT was significantly higher than that in patients with bleeding，the difference was statistically significant(P<0.05).Conclusion There is a direct relationship between prothrombin time and platelet test and the development of patients with liver cirrhosis.With the aggravation of the disease，there will be corresponding changes.It has important clinical value in the clinical diagnosis of liver cirrhosis.
, 百拇医药
Key words：Prothrombin time；Platelet test；Cirrhosis；Clinical value
肝硬化(liver cirrhosis)是臨床常见疾病，是由多种原因反复作用引起的弥漫性肝损害，临床患者主要以腹胀、黄疸为表现，早期发病较为隐匿，晚期可致癌，甚至造成死亡，严重威胁患者的健康和生命安全[1]。出血是肝硬化常见的并发症，且是导致该病患者死亡的主要原因，故对肝硬化出血症状进行有效预防，进一步有效控制病情的发展具有十分重要的作用。本文作者结合2016年5月～2017年5月在我院诊治的100例肝硬化患者临床资料，研究凝血酶原时间和血小板检验对肝硬化疾病诊断的临床价值，为临床预防肝硬化出血提供一定的参考依据，现报告如下。
1资料与方法
1.1一般资料 回顾分析2016年5月～2017年5月在我院诊治的100例肝硬化患者作为观察组，选取同期行健康体检的100例健康者作为对照组。对照组中，男43例，女57例；年龄34～74岁，平均年龄(52.10±3.45)岁。观察组中，男48例，女52例；年龄35～72岁，平均年龄(51.92±4.01)岁；病程1～7年，平均病程(3.80±1.04)年；其中有出血现象52例，无出血现象48例。两组患者在年龄、性别等基础资料方面相比，差异无统计学意义(P>0.05)，有可比性。, 百拇医药(崔洁)
关键词：凝血酶原时间；血小板检验；肝硬化；临床价值
中图分类号：R575.2 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.04.055
, http://www.100md.com
文章编号：1006-1959(2018)04-0150-02
Abstract：Objective To study the diagnostic value of prothrombin time(PT)and platelet test in patients with liver cirrhosis.Methods From May 2016 to May2017 in 100 patients with liver cirrhosis in our hospital as the observation group，and selected 100 healthy cases were concurrent healthy as control group，PT and platelet were detected，compared two groups of platelet index，PT，observation of disease group bleeding and non bleeding phenomenon of blood platelet index and PT.Results In the observation group，platelet volume(MPV)，platelet distribution width(PDW)were significantly higher than the control group，the platelet count(PLT)，plateletcrit (PCT) was significantly lower than the control group，the difference was statistically significant(P<0.05)；the observation group PT was significantly higher than the control group，the difference was statistically significant(P<0.05)no bleeding；patients with PCT，PLT was significantly lower than that of MPV，PDW，hemorrhage，PT was significantly higher than that in patients with bleeding，the difference was statistically significant(P<0.05).Conclusion There is a direct relationship between prothrombin time and platelet test and the development of patients with liver cirrhosis.With the aggravation of the disease，there will be corresponding changes.It has important clinical value in the clinical diagnosis of liver cirrhosis.
, 百拇医药
Key words：Prothrombin time；Platelet test；Cirrhosis；Clinical value
肝硬化(liver cirrhosis)是臨床常见疾病，是由多种原因反复作用引起的弥漫性肝损害，临床患者主要以腹胀、黄疸为表现，早期发病较为隐匿，晚期可致癌，甚至造成死亡，严重威胁患者的健康和生命安全[1]。出血是肝硬化常见的并发症，且是导致该病患者死亡的主要原因，故对肝硬化出血症状进行有效预防，进一步有效控制病情的发展具有十分重要的作用。本文作者结合2016年5月～2017年5月在我院诊治的100例肝硬化患者临床资料，研究凝血酶原时间和血小板检验对肝硬化疾病诊断的临床价值，为临床预防肝硬化出血提供一定的参考依据，现报告如下。
1资料与方法
1.1一般资料 回顾分析2016年5月～2017年5月在我院诊治的100例肝硬化患者作为观察组，选取同期行健康体检的100例健康者作为对照组。对照组中，男43例，女57例；年龄34～74岁，平均年龄(52.10±3.45)岁。观察组中，男48例，女52例；年龄35～72岁，平均年龄(51.92±4.01)岁；病程1～7年，平均病程(3.80±1.04)年；其中有出血现象52例，无出血现象48例。两组患者在年龄、性别等基础资料方面相比，差异无统计学意义(P>0.05)，有可比性。, 百拇医药(崔洁)