高尿酸血症生化血常规特征分析(1)
摘 要：目的 分析高尿酸血症患者的生化、血常规特点，总结临床治疗经验。方法 抽选2016年1月～2016年5月我院163例体检人员，按照尿酸结果分为两组(高尿酸组与尿酸正常组)，比较两组体重指数(BMI)、天门冬氨酸氨基转移酶(ALT)、丙氨酸氨基转移酶(AST)、γ-谷氨酰转移酶(GGT)、血脂、血常规中白细胞(WBC)、红细胞(RBC)、血红蛋白(HGB)、红细胞压积(HCT)等相关参数。结果 高尿酸组BMI高于正常组[(26.50±3.30)kg/m2 vs(24.37±2.99)kg/m2]、ALT水平高于正常组[(43.86±29.24)IU/L vs(26.67±18.19)IU/L]；AST、GGT、WBC、RBC、HGB、HCT水平均较正常组升高，组间比较差异均有统计学意义(P<0.05)。结论 根据高尿酸血症的生化、血常规特点，在降尿酸的过程中，不仅仅是关注尿酸，同时将减重、保肝、保护内皮细胞功能、抗炎等方面提供更多的治疗手段。
关键词：高尿酸血症；生化；血常规；内皮细胞
, http://www.100md.com
中图分类号：R446.1 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.06.054
文章编号：1006-1959(2018)06-0153-03
Analysis of Biochemical Blood Routine Characteristics of Hyperuricemia
SUN Qiu1，WAN Ming1，FENG Hui-fang1，FAN Li-min2
(Department of Endocrinology1，Department of Physical Examination2，416 Hospital of Nuclear Industry，the Second Affiliated Hospital of Chengdu Medical College，Chengdu 610000，Sichuan，China)
, 百拇医药
Abstract：Objective To analyze the characteristics of biochemical and blood routine in patients with hyperuricemia and to summarize the clinical experience.Methods 163 medical examiners were selected from January 2016 to May 2016 in our hospital.According to the results of uric acid，the patients were divided into two groups(hyperuricemia group and normal uric acid group).Body mass index was compared between the two groups(BMI)，aspartate aminotransferase(ALT)，alanine aminotransferase(AST)，gamma glutamyl transferase(GGT)，white blood cell， blood lipid(WBC)，red blood cell(RBC)，hemoglobin(HGB)and hematocrit(HCT)and other related parameters.Results High uric acid group BMI higher than normal group[(26.50±3.30)kg/m2 vs(24.37±2.99)kg/m2]，ALT level higher than the normal group[(43.86±29.24)IU/L vs(26.67±18.19)IU/L]；AST，GGT，WBC，RBC，HGB，HCT levels were higher than those of the normal group，the difference between groups there was statistically significant(P<0.05).Conclusion According to the biochemical and blood routine characteristics of hyperuricemia，uric acid is not only concerned in the process of lowering uric acid，but also provides more treatment for weight loss，liver protection，endothelial cell function and anti-inflammatory.
, http://www.100md.com
Key words：Hyperuricemia；Biochemistry；Blood routine；Endothelial cells
近幾十年来，人民群众的生活质量升高，高尿酸血症(HUA)患者也越来越多。HUA与痛风的关系密切，并且对糖尿病、血脂异常、慢性肾病、心脑血管等疾病，高尿酸血症是它们的独立危险因素[1]。 本研究通过对血常规及生化的各项参数的对比，分析其变化特点，分析相关生化指标与该病的关系，为高尿酸血症患者的诊治提供依据。
1 资料与方法
1.1一般资料 现选取我院2016年1月～2016年5月163例来我院体检的18岁以上的体检人员，按照尿酸结果分为高尿酸组与尿酸正常组，高尿酸组64例，尿酸正常组99例。通过对两组患者体重指数(BMI)、天门冬氨酸氨基转移酶(ALT)、丙氨酸氨基转移酶(AST)、γ-谷氨酰转移酶(GGT)、血脂、血常规包括白细胞(WBC)、红细胞(RBC)、血红蛋白(HGB)、红细胞压积(HCT)等相关参数，为高尿酸血症的诊治提供重要依据。排除标准：①严重感染；②病毒性肝炎等严重的肝部疾病；③既往有高尿酸血症或痛风病史；④大量酗酒；⑤肾功能不全；⑥免疫性疾病。, 百拇医药(孙秋 万明 冯会芳 凡利敏)
关键词：高尿酸血症；生化；血常规；内皮细胞
, http://www.100md.com
中图分类号：R446.1 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.06.054
文章编号：1006-1959(2018)06-0153-03
Analysis of Biochemical Blood Routine Characteristics of Hyperuricemia
SUN Qiu1，WAN Ming1，FENG Hui-fang1，FAN Li-min2
(Department of Endocrinology1，Department of Physical Examination2，416 Hospital of Nuclear Industry，the Second Affiliated Hospital of Chengdu Medical College，Chengdu 610000，Sichuan，China)
, 百拇医药
Abstract：Objective To analyze the characteristics of biochemical and blood routine in patients with hyperuricemia and to summarize the clinical experience.Methods 163 medical examiners were selected from January 2016 to May 2016 in our hospital.According to the results of uric acid，the patients were divided into two groups(hyperuricemia group and normal uric acid group).Body mass index was compared between the two groups(BMI)，aspartate aminotransferase(ALT)，alanine aminotransferase(AST)，gamma glutamyl transferase(GGT)，white blood cell， blood lipid(WBC)，red blood cell(RBC)，hemoglobin(HGB)and hematocrit(HCT)and other related parameters.Results High uric acid group BMI higher than normal group[(26.50±3.30)kg/m2 vs(24.37±2.99)kg/m2]，ALT level higher than the normal group[(43.86±29.24)IU/L vs(26.67±18.19)IU/L]；AST，GGT，WBC，RBC，HGB，HCT levels were higher than those of the normal group，the difference between groups there was statistically significant(P<0.05).Conclusion According to the biochemical and blood routine characteristics of hyperuricemia，uric acid is not only concerned in the process of lowering uric acid，but also provides more treatment for weight loss，liver protection，endothelial cell function and anti-inflammatory.
, http://www.100md.com
Key words：Hyperuricemia；Biochemistry；Blood routine；Endothelial cells
近幾十年来，人民群众的生活质量升高，高尿酸血症(HUA)患者也越来越多。HUA与痛风的关系密切，并且对糖尿病、血脂异常、慢性肾病、心脑血管等疾病，高尿酸血症是它们的独立危险因素[1]。 本研究通过对血常规及生化的各项参数的对比，分析其变化特点，分析相关生化指标与该病的关系，为高尿酸血症患者的诊治提供依据。
1 资料与方法
1.1一般资料 现选取我院2016年1月～2016年5月163例来我院体检的18岁以上的体检人员，按照尿酸结果分为高尿酸组与尿酸正常组，高尿酸组64例，尿酸正常组99例。通过对两组患者体重指数(BMI)、天门冬氨酸氨基转移酶(ALT)、丙氨酸氨基转移酶(AST)、γ-谷氨酰转移酶(GGT)、血脂、血常规包括白细胞(WBC)、红细胞(RBC)、血红蛋白(HGB)、红细胞压积(HCT)等相关参数，为高尿酸血症的诊治提供重要依据。排除标准：①严重感染；②病毒性肝炎等严重的肝部疾病；③既往有高尿酸血症或痛风病史；④大量酗酒；⑤肾功能不全；⑥免疫性疾病。, 百拇医药(孙秋 万明 冯会芳 凡利敏)