2014年～2016年我院质子泵抑制剂应用分析(1)
摘 要：目的 分析我院2014年～2016年质子泵抑制剂的使用情况。方法 利用HIS系统，对我院2014年～2016年PPIs的用药金额、使用频度和日均费用等进行统计分析。结果 2014年～2016年我院质子泵抑制剂总的用药金额程逐年增长趋势，2016年与2015年相比降低6.91万，3年间我院使用的PPIs不同生产厂家及品规共计7个，其中注射剂3个、口服制剂4个；金额排名前三的是注射用泮托拉唑、奥美拉唑和兰索拉唑肠溶片；3年间兰索拉唑肠溶片、注射用泮托拉唑DDDs分别位居1、2位，使用频率高；注射用泮托拉唑、奥美拉唑DDC较高，排序比均小于1表明2种药品价格水平较高。结论 注射用泮托拉唑、奥美拉唑用药金额较大等不合理现象。
关键词：质子泵抑制剂；使用频度；日均费用；用药分析
中图分类号：R95 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.08.039
, 百拇医药 文章编号：1006-1959(2018)08-0116-03
Application of Proton Pump Inhibitors in our Hospital from 2014 to 2016
FENG Qu-bo1，YAN Ting2，WU Guo-lin3
(1.Department of Pharmacy，Sichuan Forestry Center Hospital，Chengdu 610081，Sichuan，China；
2. Department of pharmacy，Affiliated Hospital of Sichuan Academy of Medical Sciences/Sichuan Provincial People's Hospital/Sichuan University of Electronic Science and Technology，Chengdu 610072；Sichuan，China；
, 百拇医药
3.Department of Pharmacy，Sichuan Maternal and Child Health Hospital，Chengdu 610045，Sichuan，China)
Abstract：Objective To analyze the use of proton pump inhibitors in our hospital from 2014 to 2016.Methods Using HIS system， the sum of money，frequency and daily average cost of PPIs used in our hospital from 2014 to 2016 were analyzed statistically.Results From 2014 to 2016，the total dosage of proton pump inhibitors in our hospital increased year by year.In 2016，the number of PPIs used in our hospital decreased by 69，100 compared with 2015.In 3 years，there were 7 different PPIs manufacturers and regulations used by our hospital， including 3 injections and 4 oral preparations；The top three in the amount was pantoprazole for injection，omeprazole，and lansoprazole enteric-coated tablets；for three years，lansoprazole enteric-coated tablets and pantoprazole DDDs for injection were ranked in the first and second positions，respectively.The use frequency is high；Pantoprazole and omeprazole DDC were higher for injection， and the ordering ratio was less than 1，indicating that the price level of the 2 drugs was higher.Conclusion The amount of pantoprazole and omeprazole for injection is unreasonable.
, 百拇医药
Key words：Proton pump inhibitor；Frequency of use；Daily average cost；Drug analysis
20世紀80年代H+，K+-ATP酶(质子泵)抑制剂(PPIs)问世，为消化性溃疡的治疗提供了更加有力的武器。质子泵抑制剂比组胺H2受体拮抗剂的抑酸作用强大而持久，是目前作用最强的抑制胃酸分泌的药物[1]。由于该类药物抑酸作用显著，针对性强，具有较好的治疗作用，受到临床的广泛应用。但一些用药风险也随之而来，如与抗血小板药物之间的相互作用、相关性腹泻及肠道感染、胃嗜络细胞增生和类瘤形成、影响相关物质吸收和增加骨折发生等[2]，为促进我院临床对该类药物的合理使用，对我院近3年PPIs的用药进行统计分析，现分析如下。
1对象与方法
1.1 研究对象 从医院HIS系统中调取2014年～2016年PPIs的使用情况包括药品名称、规格、生产地、用药金额、使用量等。应用Microsoft Excel 表格，以药品用药金额、限定日剂量(Denfined daily dose，DDD)、频度(DDDs)和日均费用(DDC)等指标对我院PPIs进行使用分析。, http://www.100md.com(冯曲波 颜婷 伍国林)
关键词：质子泵抑制剂；使用频度；日均费用；用药分析
中图分类号：R95 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.08.039
, 百拇医药 文章编号：1006-1959(2018)08-0116-03
Application of Proton Pump Inhibitors in our Hospital from 2014 to 2016
FENG Qu-bo1，YAN Ting2，WU Guo-lin3
(1.Department of Pharmacy，Sichuan Forestry Center Hospital，Chengdu 610081，Sichuan，China；
2. Department of pharmacy，Affiliated Hospital of Sichuan Academy of Medical Sciences/Sichuan Provincial People's Hospital/Sichuan University of Electronic Science and Technology，Chengdu 610072；Sichuan，China；
, 百拇医药
3.Department of Pharmacy，Sichuan Maternal and Child Health Hospital，Chengdu 610045，Sichuan，China)
Abstract：Objective To analyze the use of proton pump inhibitors in our hospital from 2014 to 2016.Methods Using HIS system， the sum of money，frequency and daily average cost of PPIs used in our hospital from 2014 to 2016 were analyzed statistically.Results From 2014 to 2016，the total dosage of proton pump inhibitors in our hospital increased year by year.In 2016，the number of PPIs used in our hospital decreased by 69，100 compared with 2015.In 3 years，there were 7 different PPIs manufacturers and regulations used by our hospital， including 3 injections and 4 oral preparations；The top three in the amount was pantoprazole for injection，omeprazole，and lansoprazole enteric-coated tablets；for three years，lansoprazole enteric-coated tablets and pantoprazole DDDs for injection were ranked in the first and second positions，respectively.The use frequency is high；Pantoprazole and omeprazole DDC were higher for injection， and the ordering ratio was less than 1，indicating that the price level of the 2 drugs was higher.Conclusion The amount of pantoprazole and omeprazole for injection is unreasonable.
, 百拇医药
Key words：Proton pump inhibitor；Frequency of use；Daily average cost；Drug analysis
20世紀80年代H+，K+-ATP酶(质子泵)抑制剂(PPIs)问世，为消化性溃疡的治疗提供了更加有力的武器。质子泵抑制剂比组胺H2受体拮抗剂的抑酸作用强大而持久，是目前作用最强的抑制胃酸分泌的药物[1]。由于该类药物抑酸作用显著，针对性强，具有较好的治疗作用，受到临床的广泛应用。但一些用药风险也随之而来，如与抗血小板药物之间的相互作用、相关性腹泻及肠道感染、胃嗜络细胞增生和类瘤形成、影响相关物质吸收和增加骨折发生等[2]，为促进我院临床对该类药物的合理使用，对我院近3年PPIs的用药进行统计分析，现分析如下。
1对象与方法
1.1 研究对象 从医院HIS系统中调取2014年～2016年PPIs的使用情况包括药品名称、规格、生产地、用药金额、使用量等。应用Microsoft Excel 表格，以药品用药金额、限定日剂量(Denfined daily dose，DDD)、频度(DDDs)和日均费用(DDC)等指标对我院PPIs进行使用分析。, http://www.100md.com(冯曲波 颜婷 伍国林)