高压氧治疗胸段脊髓损伤的临床分析(1)
摘 要：目的 探讨高压氧在治疗胸段脊髓损伤患者的效果。方法 选择2014年3月～2016年3月我院收治92例胸段脊髓损伤患者，随机分为对照组和高压氧组，各46例，伤后1～2周内均行脊髓减压手术，术后两组均使用常规药物治疗，高压氧组在此基础上配合高压氧治疗，两组治疗时间均为180 d，随后比较两组治疗效果。结果 高压氧组总有效率为93.57%，高于对照组的76.72%，差异具有统计学意义(P<0.05)；高压氧组在治疗2个疗程前，治疗效果不明显，治疗3个疗程后，开始出现较好的治疗效果，且在治疗6个疗程后达到高峰并趋于稳定。结论 常规药物联合高压氧综合治疗脊髓损伤，可以有效促进患者脊髓功能恢复，降低致残率，成为一种安全、有效的脊髓损伤治疗手段。
关键词：胸段脊髓损伤；高压氧；血管内皮细胞生长因子
中图分类号：R651.2；R459.5 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.10.025
, 百拇医药
文章编号：1006-1959(2018)10-0084-03
Clinical Analysis of Hyperbaric Oxygen Therapy for Thoracic Spinal Injury
LU Wan1，HUANG Zong-guo1，LIAO Sheng2，LIU Yun3，ZHANG Zhong-rong2，YANG Xing-hua2，LIU Xing2
(1.Department of Hyperbaric Oxygen，No.452 Hospital of PLA，Chengdu 610083，Sichuan，China；
2.Department of Trauma Micro Surgery，No.324 Hospital of PLA，Chongqing 400020，China；
, 百拇医药
3.Department of Urology，Second Affiliated Hospital of the Third Military Medical University，Chongqing 400037，China)
Abstract：Objective To investigate the effect of hyperbaric oxygen in the treatment of thoracic spinal injury.Methods From March 2014 to March 2016，92 patients with thoracic spinal injury in our hospital were randomly divided into control group and hyperbaric oxygen group，46 cases each group.Decompression of spinal cord was performed within 1 to 2 weeks after injury.Both groups were treated with conventional drugs.The hyperbaric oxygen group was treated with hyperbaric oxygen on the basis of this treatment.The treatment time was 180 d in both groups.The treatment effects of the two groups were then compared.Results The total effective rate of hyperbaric oxygen group was 93.57%，which was higher than 76.72% of the control group，the difference was statistically significant (P<0.05).The hyperbaric oxygen group had no obvious treatment effect before 2 courses of treatment.After 3 courses of treatment，good therapeutic effects began to appear，and peaked after 6 courses of treatment，becoming steady.Conclusion Conventional drugs combined with hyperbaric oxygen therapy for spinal cord injury can effectively promote the recovery of spinal cord function and reduce the disability rate，and become a safe and effective treatment for spinal injury.
, 百拇医药
Key words：Thoracic spinal injury；Hyperbaric oxygen；Vascular endothelial growth factor
脊髓損伤(spinal injury)是脊柱损伤最严重的并发症，主要因直接或间接暴力造成脊柱骨折移位或碎骨片突出椎管内造成脊髓损伤，从而导致损伤水平以下感觉、运动障碍或消失，大小便失禁等症状，严重影响患者生活质量[1]。脊髓损伤节段越高，躯体及四肢损害范围越广，临床上治疗难度较大，效果欠佳，常留有不同程度的功能障碍，瘫痪发生率也较高[2]。研究发现高压氧(hyperbaric oxygen，HPO)治疗能有效促进脊髓损伤功能的恢复，已成为脊髓损伤后患者功能康复的重要治疗手段[3]。2014年3月～2016年3月，我院收治了92例胸段脊髓损伤(thoracic spinal cord injury，TSCI)患者，并对其进行了高压氧治疗，治疗效果较满意，现报告如下。, 百拇医药(陆晚 黄宗国 廖胜)
关键词：胸段脊髓损伤；高压氧；血管内皮细胞生长因子
中图分类号：R651.2；R459.5 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.10.025
, 百拇医药
文章编号：1006-1959(2018)10-0084-03
Clinical Analysis of Hyperbaric Oxygen Therapy for Thoracic Spinal Injury
LU Wan1，HUANG Zong-guo1，LIAO Sheng2，LIU Yun3，ZHANG Zhong-rong2，YANG Xing-hua2，LIU Xing2
(1.Department of Hyperbaric Oxygen，No.452 Hospital of PLA，Chengdu 610083，Sichuan，China；
2.Department of Trauma Micro Surgery，No.324 Hospital of PLA，Chongqing 400020，China；
, 百拇医药
3.Department of Urology，Second Affiliated Hospital of the Third Military Medical University，Chongqing 400037，China)
Abstract：Objective To investigate the effect of hyperbaric oxygen in the treatment of thoracic spinal injury.Methods From March 2014 to March 2016，92 patients with thoracic spinal injury in our hospital were randomly divided into control group and hyperbaric oxygen group，46 cases each group.Decompression of spinal cord was performed within 1 to 2 weeks after injury.Both groups were treated with conventional drugs.The hyperbaric oxygen group was treated with hyperbaric oxygen on the basis of this treatment.The treatment time was 180 d in both groups.The treatment effects of the two groups were then compared.Results The total effective rate of hyperbaric oxygen group was 93.57%，which was higher than 76.72% of the control group，the difference was statistically significant (P<0.05).The hyperbaric oxygen group had no obvious treatment effect before 2 courses of treatment.After 3 courses of treatment，good therapeutic effects began to appear，and peaked after 6 courses of treatment，becoming steady.Conclusion Conventional drugs combined with hyperbaric oxygen therapy for spinal cord injury can effectively promote the recovery of spinal cord function and reduce the disability rate，and become a safe and effective treatment for spinal injury.
, 百拇医药
Key words：Thoracic spinal injury；Hyperbaric oxygen；Vascular endothelial growth factor
脊髓損伤(spinal injury)是脊柱损伤最严重的并发症，主要因直接或间接暴力造成脊柱骨折移位或碎骨片突出椎管内造成脊髓损伤，从而导致损伤水平以下感觉、运动障碍或消失，大小便失禁等症状，严重影响患者生活质量[1]。脊髓损伤节段越高，躯体及四肢损害范围越广，临床上治疗难度较大，效果欠佳，常留有不同程度的功能障碍，瘫痪发生率也较高[2]。研究发现高压氧(hyperbaric oxygen，HPO)治疗能有效促进脊髓损伤功能的恢复，已成为脊髓损伤后患者功能康复的重要治疗手段[3]。2014年3月～2016年3月，我院收治了92例胸段脊髓损伤(thoracic spinal cord injury，TSCI)患者，并对其进行了高压氧治疗，治疗效果较满意，现报告如下。, 百拇医药(陆晚 黄宗国 廖胜)