乌鲁木齐地区正常妊娠妇女和不同次数自然流产妇女TORCH感染比较(1)
摘 要：目的 比较乌鲁木齐正常妊娠妇女和不同自然流产次数妇女血清TORCH感染情况。方法 选取我院420例正常妊娠组妇女、451例1～2次流产组妇女和430例≥3次流产组妇女，采用ELISA法检测血清中特异性TORCH系列，包括弓形虫、巨细胞病毒、风疹病毒、单纯疱疹病毒IgM并比较其阳性率。结果 正常妊娠组TOX、CMV、RUV、HSV IgM阳性率分别为2.62%、5.24%、3.10%、6.67%，阳性率合计为17.62%；1～2次流产组妇女中上述抗体阳性率分别为7.10%、9.53%、7.76%、13.53%，阳性率合计为37.92%；≥3次流产组妇女上述抗体阳性率分别为3.49%、4.42%、3.95%、7.44%，阳性率合计为19.30%。1～2次流产组女性TORCH感染高于正常妊娠组(P<0.05)，而≥3次流产组妇女TORCH感染与正常妊娠组比较，差异无统计学意义(P>0.05)。结论 有1～2次自然流产的女性流产发生可能与TORCH感染有关，≥3次自然流产的女性流产发生与TORCH感染无明显相关性，可能与其它因素有关。建议在孕前进行TORCH感染筛查，尤其是对1～2次自然流产的女性，应重点筛查，做好孕期预防保健工作，以提高优生优育质量。
, http://www.100md.com
关键词：TORCH感染；正常妊娠；自然流产
中图分类号：R714.21 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.17.049
文章编号：1006-1959(2018)17-0155-03
Abstract：Objective To compare the serum TORCH infection in women with normal pregnancy and women with different spontaneous abortions in Urumqi.Methods A total of 420 normal pregnant women，451 women with 1 to 2 spontaneous abortions and 430 women with≥3 spontaneous abortions were enrolled in our hospital.Serum specific TORCH series Toxoplasma gondii，cytomegalovirus，rubella virus，herpes simplex virus IgM were detected by ELISA and their positive rates were compared.Results The positive rates of TOX，CMV，RUV and HSV IgM in normal pregnancy group were 2.62%，5.24%，3.10% and 6.67%，respectively.The positive rate was 17.62%；the positive rate of these antibodies in women in 1～2 abortion groups was 7.10%，9.53%，7.76%，13.53%，and the positive rate was 37.92%；The positive rates of these antibodies in≥3 abortion women were 3.49%，4.42%，3.95% and 7.44%，respectively，and the positive rate was 19.30%.The TORCH infection in females in 1 to 2 abortion group was higher than that in normal pregnancy group(P<0.05)，but there was no significant difference in TORCH infection between women in≥3 abortion groups compared with normal pregnancy group(P>0.05). Conclusion Female with 1 or 2 spontaneous abortions may be associated with TORCH infection.Female with≥3 spontaneous abortions have no significant correlation with TORCH infection，which may be related to other factors.It is recommended to screen for TORCH infection before pregnancy，especially for women with 1 to 2 spontaneous abortions，and should focus on screening and prevent pregnancy and health care during pregnancy to improve the quality of prenatal and postnatal care.
, 百拇医药
Key words：TORCH infection；Normal pregnancy；Spontaneous abortion
TORCH作為一组微生物，孕妇感染后，能通过胎盘或产道引起宫内感染，导致流产、死胎或胎儿生长迟缓、畸形，甚至新生儿期感染或及青春期出现发育障碍，而孕妇几乎不表现出明显症状，在妇产科学中称为TORCH综合征，已日益受到妇产科和儿科的重视。TORCH中T即弓形体病(toxoplasmosis)、O即(others)，主要有柯萨奇病毒、乙型肝炎病毒、麻疹病毒、李司忒氏菌、伤寒沙门氏菌等，致各微生物同名病；R即风疹病毒(rubella virus)致风疹；C即巨细胞病毒(cytomegalovirus，CMV)致巨细胞包涵体病；H即单纯疱疹病毒Ⅰ型和Ⅱ型(hespes simplelvimstypos Ⅰ and Ⅱ)致生殖器疱疹。现用ELISA法对鲁木齐地区420例正常妊娠妇女、451例1～2次自然流产组妇女和430例≥3次自然流产组妇女进行TORCH系列病原体血清抗体检测，以探讨TORCH感染与自然流产次数的关系。, http://www.100md.com(张力鹏 黄修菊 林玉婷)
, http://www.100md.com
关键词：TORCH感染；正常妊娠；自然流产
中图分类号：R714.21 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.17.049
文章编号：1006-1959(2018)17-0155-03
Abstract：Objective To compare the serum TORCH infection in women with normal pregnancy and women with different spontaneous abortions in Urumqi.Methods A total of 420 normal pregnant women，451 women with 1 to 2 spontaneous abortions and 430 women with≥3 spontaneous abortions were enrolled in our hospital.Serum specific TORCH series Toxoplasma gondii，cytomegalovirus，rubella virus，herpes simplex virus IgM were detected by ELISA and their positive rates were compared.Results The positive rates of TOX，CMV，RUV and HSV IgM in normal pregnancy group were 2.62%，5.24%，3.10% and 6.67%，respectively.The positive rate was 17.62%；the positive rate of these antibodies in women in 1～2 abortion groups was 7.10%，9.53%，7.76%，13.53%，and the positive rate was 37.92%；The positive rates of these antibodies in≥3 abortion women were 3.49%，4.42%，3.95% and 7.44%，respectively，and the positive rate was 19.30%.The TORCH infection in females in 1 to 2 abortion group was higher than that in normal pregnancy group(P<0.05)，but there was no significant difference in TORCH infection between women in≥3 abortion groups compared with normal pregnancy group(P>0.05). Conclusion Female with 1 or 2 spontaneous abortions may be associated with TORCH infection.Female with≥3 spontaneous abortions have no significant correlation with TORCH infection，which may be related to other factors.It is recommended to screen for TORCH infection before pregnancy，especially for women with 1 to 2 spontaneous abortions，and should focus on screening and prevent pregnancy and health care during pregnancy to improve the quality of prenatal and postnatal care.
, 百拇医药
Key words：TORCH infection；Normal pregnancy；Spontaneous abortion
TORCH作為一组微生物，孕妇感染后，能通过胎盘或产道引起宫内感染，导致流产、死胎或胎儿生长迟缓、畸形，甚至新生儿期感染或及青春期出现发育障碍，而孕妇几乎不表现出明显症状，在妇产科学中称为TORCH综合征，已日益受到妇产科和儿科的重视。TORCH中T即弓形体病(toxoplasmosis)、O即(others)，主要有柯萨奇病毒、乙型肝炎病毒、麻疹病毒、李司忒氏菌、伤寒沙门氏菌等，致各微生物同名病；R即风疹病毒(rubella virus)致风疹；C即巨细胞病毒(cytomegalovirus，CMV)致巨细胞包涵体病；H即单纯疱疹病毒Ⅰ型和Ⅱ型(hespes simplelvimstypos Ⅰ and Ⅱ)致生殖器疱疹。现用ELISA法对鲁木齐地区420例正常妊娠妇女、451例1～2次自然流产组妇女和430例≥3次自然流产组妇女进行TORCH系列病原体血清抗体检测，以探讨TORCH感染与自然流产次数的关系。, http://www.100md.com(张力鹏 黄修菊 林玉婷)