头颅MRI—DWI病灶数量及部位对脑梗死复发预测意义(1)
摘 要：目的 探討头颅磁共振弥散加权成像病灶数量及部位对脑梗死复发的预测意义。方法 收集我院神经内科确诊的124例首发急性脑梗死患者的临床资料及实验数据。根据病灶的数量分为：多发病灶(87例)与单发病灶(37例)；根据部位分为：①单发皮层病灶(1例)与单发深部病灶(36例)；②相同供血区多发病灶(38例)与不同供血区多发病灶(49例)；根据是否复发分为复发组及未复发组，每组62例。将患者一般资料、症状性颅内外动脉狭窄、LDL-C、HDL-C、T-C、TG、NIHSS评分、抗血小板药物应用及他汀应用行单因素及多因素Logistic回归分析。结果 经单因素分析提示，多发病灶与单发病灶2年内复发情况比较，差异具有统计学意义(P<0.05)。单发皮层病灶与单发深部病灶比较，差异无统计学意义(P>0.05)；不同供血区多发病灶与相同供血区多发病灶比较，差异具有统计学意义(P<0.05)。经多因素Logistic回归分析提示多发病灶(P<0.05)、不同供血区多发病灶(P<0.05)、糖尿病及症状性颅内外动脉狭窄可能对首发急性脑梗死患者2年内复发具有预测意义。结论 多发病灶、不同供血区多发病灶、症状性颅内外动脉狭窄及糖尿病可能对首发急性脑梗死患者2年内复发具有一定预测意义。
, 百拇医药
关键词：急性脑梗死；弥散加权成像；复发；病灶数量；病灶部位
中图分类号：R743 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.22.052
文章编号：1006-1959(2018)22-0172-03
The Significance of the Number and Location of MRI-DWI Lesions in Predicting the Recurrence of Cerebral Infarction
LIU Ran
(Department of Neurology，Tianjin Huanhu Hospital，Tianjin 300350，China)
, 百拇医药
Abstract：Objective To investigate the predictive significance of the number and location of brain diffusion-weighted imaging lesions in predicting the recurrence of cerebral infarction.Methods The clinical data and experimental data of 124 patients with acute cerebral infarction diagnosed by neurology in our hospital were collected.According to the number of lesions： multiple lesions (87 cases) and single lesions (37 cases)；According to the location：① single cortical lesion (1 case) and single deep lesion (36 cases)；②Multiple lesions in the same blood supply area (38 cases) and multiple lesions in different blood supply areas (49 cases).The patients were divided into recurrence group and non-recurrence group according to whether they recurred， 62 cases in each group.Univariate and multivariate Logistic regression was performed on general data， symptomatic extracranial artery stenosis， LDL-C，HDL-C，T-C，TG，NIHSS score， antiplatelet drug use and statins.Results Single factor analysis showed that the recurrence of multiple lesions was significantly different from that of single lesions within 2 years，the difference was statistically significant(P<0.05). There was no significant difference between single cortical lesions and single deep lesions(P>0.05).Compared with multiple lesions in the same blood supply area， the statistical significance was significant (P<0.05).Multivariate Logistic regression analysis showed that there were multiple lesions(P<0.05) and multiple lesions in different blood supply areas(P<0.05)，diabetes mellitus and symptomatic extracranial artery stenosis might predict the recurrence of acute cerebral infarction within 2 years. Conclusion Multiple lesions， multiple lesions in different blood supply areas， symptomatic extracranial artery stenosis and diabetes may be useful in predicting recurrence in the first acute cerebral infarction patients within 2 years., 百拇医药(刘然)
, 百拇医药
关键词：急性脑梗死；弥散加权成像；复发；病灶数量；病灶部位
中图分类号：R743 文献标识码：A DOI：10.3969/j.issn.1006-1959.2018.22.052
文章编号：1006-1959(2018)22-0172-03
The Significance of the Number and Location of MRI-DWI Lesions in Predicting the Recurrence of Cerebral Infarction
LIU Ran
(Department of Neurology，Tianjin Huanhu Hospital，Tianjin 300350，China)
, 百拇医药
Abstract：Objective To investigate the predictive significance of the number and location of brain diffusion-weighted imaging lesions in predicting the recurrence of cerebral infarction.Methods The clinical data and experimental data of 124 patients with acute cerebral infarction diagnosed by neurology in our hospital were collected.According to the number of lesions： multiple lesions (87 cases) and single lesions (37 cases)；According to the location：① single cortical lesion (1 case) and single deep lesion (36 cases)；②Multiple lesions in the same blood supply area (38 cases) and multiple lesions in different blood supply areas (49 cases).The patients were divided into recurrence group and non-recurrence group according to whether they recurred， 62 cases in each group.Univariate and multivariate Logistic regression was performed on general data， symptomatic extracranial artery stenosis， LDL-C，HDL-C，T-C，TG，NIHSS score， antiplatelet drug use and statins.Results Single factor analysis showed that the recurrence of multiple lesions was significantly different from that of single lesions within 2 years，the difference was statistically significant(P<0.05). There was no significant difference between single cortical lesions and single deep lesions(P>0.05).Compared with multiple lesions in the same blood supply area， the statistical significance was significant (P<0.05).Multivariate Logistic regression analysis showed that there were multiple lesions(P<0.05) and multiple lesions in different blood supply areas(P<0.05)，diabetes mellitus and symptomatic extracranial artery stenosis might predict the recurrence of acute cerebral infarction within 2 years. Conclusion Multiple lesions， multiple lesions in different blood supply areas， symptomatic extracranial artery stenosis and diabetes may be useful in predicting recurrence in the first acute cerebral infarction patients within 2 years., 百拇医药(刘然)