糖尿病性胃轻瘫调节胃生理功能的相关组织细胞研究(3)
综上所述,胃正常生理状态的调节需要几种关键组织细胞参于,在糖尿病性胃轻瘫的发病过程中,可能存在相关组织细胞功能异常。包括胃外来神经支配异常,Cajal间质细胞受损和胃体肌壁巨噬细胞改变等方面。巨噬细胞可能是引起其他类型细胞潜在损伤的关键细胞类型,可能影响目前糖尿病性胃轻瘫管理,需要进一步研究明确。
参考文献:
[1]Koch KL.Diabetic gastroparesis[J].Gastroenterol Clin NA,2015,44(1):39-57.
[2]Rok SC,Richard L,Cathy S,et al.Risk of Gastroparesis in Subjects with Type 1 and 2 Diabetes in the Genera l Population[J].Am J Gastroenterol,2012,107(1):82-88.
, 百拇医药
[3]Stevens JE,Jones KL,Rayner CK,et al.Pathophysiology and pharmacotherapy of gastroparesis: current and future perspectives[J].Expert Opin Pharmacother,2013,14(9):1171-1186.
[4]Panda H,Mitchell P,Curley M,et al.Prospective evaluation of gastric neurostimulation for diabetic gastroparesis in Canada[J].Can J Gastroenterol Hepatol,2015,29(4):198-202.
[5]Singla R,Homko C,Schey R,et al.Diabetes-related autoantibodies in diabetic gastroparesis[J].Dig Dis Sci,2015,60(6):1733-1737.
, 百拇医药
[6]Thazhath SS,Jones KL,Horowitz M,et al.Diabetic gastroparesis: recent insights into pathophysiology and implications for management[J].Expert Rev Gastroenterol Hepatol,2013,7(2):127-139.
[7]Leila N,Simon J,Gianrico F.Macrophages in diabetic gastroparesis- the missing link?[J].Neurogastroenterol Motil,2015,27(1):7-18.
[8]Yarandi SS,Srinivasan S.Diabetic gastrointestinal motility disorders and the role of enteric nervous system: current status and future directions[J].Neurogastroenterol Motil,2014,26(6):611-624.
, http://www.100md.com
[9]Horvath VJ,Izbeki F,Lengyel C,et al.Diabetic gastroparesis:functional/morphologic background,diagnosis,and treatment options[J].Curr Diab Rep,2014,14(9):527.
[10]Faussone MS,Grover M,Pasricha PJ,et al.Ultrastructural differences between diabetic and idiopathic gastroparesis[J].J Cell Mol Med,2012,16(2):1573-1581.
[11]杜政庭.胃Cajal間质细胞在糖尿病胃轻瘫中的作用[J].临床医药文献杂志,2016,3(58):11681-11682.
[12]Van VJ,Hain SJ,Grasso S,et al.Effects of Osteopathic Manipulative Treatment on Diabetic Gastroparesis[J].J Am Osteopath Assoc,2015,115(7):452-458.
, 百拇医药
[13]Farrugia G.Histologic changes in diabetic gastroparesis[J].Gastroenterol Clin North Am,2015,44(1):31-38.
[14]Lies B,Groneberg D,Friebe A.Toward a better understanding of gastrointestinal nitrergic neuromuscular transmission[J].Neurogastroenterol Motil,2014,26(5):901-912.
[15]高彩霞,徐志强,祝捷,等.Cajal 间质细胞与肠神经系统在糖尿病胃轻瘫发病中的作用[J].实用中西医结合临床,2015,15(6):87-90.
[16]Kurahashi M,Mutafova-Yambolieva V,Koh SD,et al.Platelet-derived growth factor receptor-α-positive cells and not smooth muscle cells mediate purinergic hyperpolarization in murine colonic muscles[J].Am J Physiol Cell Physiol,2014,307(6):C561-C570., 百拇医药(房芳 赵丽英 刘迎春)
参考文献:
[1]Koch KL.Diabetic gastroparesis[J].Gastroenterol Clin NA,2015,44(1):39-57.
[2]Rok SC,Richard L,Cathy S,et al.Risk of Gastroparesis in Subjects with Type 1 and 2 Diabetes in the Genera l Population[J].Am J Gastroenterol,2012,107(1):82-88.
, 百拇医药
[3]Stevens JE,Jones KL,Rayner CK,et al.Pathophysiology and pharmacotherapy of gastroparesis: current and future perspectives[J].Expert Opin Pharmacother,2013,14(9):1171-1186.
[4]Panda H,Mitchell P,Curley M,et al.Prospective evaluation of gastric neurostimulation for diabetic gastroparesis in Canada[J].Can J Gastroenterol Hepatol,2015,29(4):198-202.
[5]Singla R,Homko C,Schey R,et al.Diabetes-related autoantibodies in diabetic gastroparesis[J].Dig Dis Sci,2015,60(6):1733-1737.
, 百拇医药
[6]Thazhath SS,Jones KL,Horowitz M,et al.Diabetic gastroparesis: recent insights into pathophysiology and implications for management[J].Expert Rev Gastroenterol Hepatol,2013,7(2):127-139.
[7]Leila N,Simon J,Gianrico F.Macrophages in diabetic gastroparesis- the missing link?[J].Neurogastroenterol Motil,2015,27(1):7-18.
[8]Yarandi SS,Srinivasan S.Diabetic gastrointestinal motility disorders and the role of enteric nervous system: current status and future directions[J].Neurogastroenterol Motil,2014,26(6):611-624.
, http://www.100md.com
[9]Horvath VJ,Izbeki F,Lengyel C,et al.Diabetic gastroparesis:functional/morphologic background,diagnosis,and treatment options[J].Curr Diab Rep,2014,14(9):527.
[10]Faussone MS,Grover M,Pasricha PJ,et al.Ultrastructural differences between diabetic and idiopathic gastroparesis[J].J Cell Mol Med,2012,16(2):1573-1581.
[11]杜政庭.胃Cajal間质细胞在糖尿病胃轻瘫中的作用[J].临床医药文献杂志,2016,3(58):11681-11682.
[12]Van VJ,Hain SJ,Grasso S,et al.Effects of Osteopathic Manipulative Treatment on Diabetic Gastroparesis[J].J Am Osteopath Assoc,2015,115(7):452-458.
, 百拇医药
[13]Farrugia G.Histologic changes in diabetic gastroparesis[J].Gastroenterol Clin North Am,2015,44(1):31-38.
[14]Lies B,Groneberg D,Friebe A.Toward a better understanding of gastrointestinal nitrergic neuromuscular transmission[J].Neurogastroenterol Motil,2014,26(5):901-912.
[15]高彩霞,徐志强,祝捷,等.Cajal 间质细胞与肠神经系统在糖尿病胃轻瘫发病中的作用[J].实用中西医结合临床,2015,15(6):87-90.
[16]Kurahashi M,Mutafova-Yambolieva V,Koh SD,et al.Platelet-derived growth factor receptor-α-positive cells and not smooth muscle cells mediate purinergic hyperpolarization in murine colonic muscles[J].Am J Physiol Cell Physiol,2014,307(6):C561-C570., 百拇医药(房芳 赵丽英 刘迎春)