儿童呼吸道感染者肺炎支原体及肺炎衣原体特异性抗体检测临床意义(1)
摘要：目的 探究兒童呼吸道感染者肺炎支原体及肺炎衣原体特异性抗体检测临床意义。方法 选择我院2018年1月～8月收治的85例呼吸道感染患儿设为研究组，另选择同期在我院进行健康体检的85例儿童设为对照组，对照组采用ELISA法检测肺炎支原体及衣原体，研究组在此基础上行咽拭子培养法检测，比较两组肺炎支原体、衣原体抗体检出率，ELISA法与咽拭子培养法对肺炎支原体、衣原体抗体的阳性检出率，分析研究组呼吸道感染性疾病中肺炎支原体、衣原体抗体阳性分布情况。结果 研究组患儿肺炎支原体抗体MP-IgM抗体、MP-IgA抗体、MP-IgG抗体及肺炎衣原体特异性抗体CP-IgM抗体、CP-IgG抗体的检出率均高于对照组儿童，差异有统计学意义(P<0.05);ELISA法对肺炎支原体特异性抗体阳性的检出率为54.12%高于咽拭子培养法的36.47%，组间对比具有统计学意义(P<0.05);ELISA法对肺炎衣原体特异性抗体阳性的检出率为58.82%高于咽拭子培养法的37.65%，差异有统计学意义(P<0.05);肺炎支原体、肺炎衣原体抗体阳性在各种儿童呼吸道感染性疾病中均有表现，其中，肺炎和支气管肺炎的阳性检出率较咽炎、扁桃体炎均较高。结论 肺炎支原体、肺炎衣原体是引发肺炎和支气管肺炎感染的主要病原菌。
, 百拇医药
关键词：儿童;呼吸道感染;肺炎支原体;肺炎衣原体;抗体检测;ELISA法;咽拭子培养法
中图分类号：R725.6 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.03.029
文章编号：1006-1959(2019)03-0096-03
Abstract：Objective To investigate the clinical significance of detection of specific antibodies against mycoplasma pneumoniae and chlamydia pneumoniae in children with respiratory infection.Methods 85 children with respiratory infection admitted to our hospital from January to August 2018 were selected as study group，while 85 children who underwent physical examination in our hospital were selected as control group.In the control group，mycoplasma pneumoniae and chlamydia pneumoniae were detected by ELISA method，and on this basis the throat swab culture method was used in the study group.The detection rates of mycoplasma pneumoniae and chlamydia pneumoniae antibodies were compared between the two groups.The positive rates of mycoplasma pneumoniae and chlamydia antibodies were detected by ELISA and throat swab and the positive distribution of mycoplasma pneumoniae and chlamydia pneumoniae antibody in respiratory infectious diseases were analyzed in study group.Results The detection rate of mycoplasma pneumoniae antibody MP-IgM antibody， MP-IgA antibody， MP-IgG antibody，chlamydia pneumoniae specific antibody CP-IgM antibody and CP-IgG antibody in the study group were higher than those in the control group，the difference was statistically significant (P<0.05).The positive rate of specific antibody against mycoplasma pneumoniae by ELISA method was 54.12%， which was higher than that by throat swab culture method 36.47%.The comparison between groups was statistically significant(P<0.05).The positive rate of specific antibody against chlamydia pneumoniae by ELISA method was 58.82%， which was higher than that by throat swab culture method 37.65%，the difference was statistically significant(P<0.05).Mycoplasma pneumoniae， chlamydia pneumoniae antibody positive in all kinds of children respiratory infectious diseases，the positive rate of pneumonia and bronchopneumonia was higher than that of pharyngitis and tonsillitis.Conclusion Mycoplasma pneumoniae and chlamydia pneumoniae are the main pathogens causing pneumonia and bronchopneumonia., http://www.100md.com(李娇 林琳)
, 百拇医药
关键词：儿童;呼吸道感染;肺炎支原体;肺炎衣原体;抗体检测;ELISA法;咽拭子培养法
中图分类号：R725.6 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.03.029
文章编号：1006-1959(2019)03-0096-03
Abstract：Objective To investigate the clinical significance of detection of specific antibodies against mycoplasma pneumoniae and chlamydia pneumoniae in children with respiratory infection.Methods 85 children with respiratory infection admitted to our hospital from January to August 2018 were selected as study group，while 85 children who underwent physical examination in our hospital were selected as control group.In the control group，mycoplasma pneumoniae and chlamydia pneumoniae were detected by ELISA method，and on this basis the throat swab culture method was used in the study group.The detection rates of mycoplasma pneumoniae and chlamydia pneumoniae antibodies were compared between the two groups.The positive rates of mycoplasma pneumoniae and chlamydia antibodies were detected by ELISA and throat swab and the positive distribution of mycoplasma pneumoniae and chlamydia pneumoniae antibody in respiratory infectious diseases were analyzed in study group.Results The detection rate of mycoplasma pneumoniae antibody MP-IgM antibody， MP-IgA antibody， MP-IgG antibody，chlamydia pneumoniae specific antibody CP-IgM antibody and CP-IgG antibody in the study group were higher than those in the control group，the difference was statistically significant (P<0.05).The positive rate of specific antibody against mycoplasma pneumoniae by ELISA method was 54.12%， which was higher than that by throat swab culture method 36.47%.The comparison between groups was statistically significant(P<0.05).The positive rate of specific antibody against chlamydia pneumoniae by ELISA method was 58.82%， which was higher than that by throat swab culture method 37.65%，the difference was statistically significant(P<0.05).Mycoplasma pneumoniae， chlamydia pneumoniae antibody positive in all kinds of children respiratory infectious diseases，the positive rate of pneumonia and bronchopneumonia was higher than that of pharyngitis and tonsillitis.Conclusion Mycoplasma pneumoniae and chlamydia pneumoniae are the main pathogens causing pneumonia and bronchopneumonia., http://www.100md.com(李娇 林琳)