中药内服联合外洗治疗复发性霉菌性阴道炎的临床疗效观察(1)
摘要：目的 探讨中药内服联合外洗对复发性霉菌性阴道炎的治疗效果。方法 随机选取2015年5月～2017年5月本院收治的102例复发性阴道炎患者，随机分为对照组和治疗组，各51例。对照组采用制霉菌素阴道栓联合口服制霉菌素治疗，治疗组采用加味桂芍四妙汤配合中医外洗治疗，对比两组治疗效果，随访观察两组患者复发情况。结果 治疗组总有效率为92.17%，高于对照组的82.35%，差异有统计学意义(P<0.05);随访发现对照组复发3例(5.89%)，治疗组复发1例(1.96%)，差异有统计学意义(P<0.05)。结论 中医内服联合外洗治疗复发性霉菌性阴道炎临床效果较好，复发率低，值得应用。
关键词：复发性霉菌性阴道炎;加味桂芍四妙汤;制霉菌素
中图分类号：R271.9 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.03.055
, 百拇医药
文章编号：1006-1959(2019)03-0165-02
Abstract：Objective To investigate the therapeutic effect of Chinese herbal medicine combined with external washing on recurrent fungal vaginitis. Methods A total of 102 patients with recurrent vaginitis admitted to our hospital from May 2015 to May 2017 were randomly divided into control group and treatment group， 51 cases each. The control group was treated with nystatin vaginal suppository combined with oral nystatin. The treatment group was treated with Jiawei Guishao Simiao Decoction combined with external Chinese medicine treatment. The therapeutic effects of the two groups were compared. The recurrence of the two groups was followed up.Results The total effective rate was 92.17% in the treatment group， which was higher than that in the control group 82.35%，the difference was statistically significant (P<0.05).At the follow-up， 3 patients (5.89%) relapsed in the control group and 1 patient (1.96%) in the treatment group，the difference was statistically significant (P<0.05).Conclusion TCM oral administration combined with external washing for recurrent mycotic vaginitis has a good clinical effect and low recurrence rate， which is worthy of application.
, 百拇医药
Key words：Recurrent fungal vaginitis;Jiawei Guishao Simiao Decoction;Nystatin
霉菌性陰道炎(vulvoaginal Candidasis，VVC)在临床上比较常见，约75%的女性一生中至少发病一次[1]。其发生的原因多与患者的年龄、性生活情况、妊娠状态、存在糖尿病病史、日常滥用抗生素等有一定程度的关系。医学上将经临床治疗后临床症状及体征消失，真菌检查阴性后又出现真菌学以证实的症状称为复发，若1年内发作4次或以上称复发性霉菌性阴道炎[1，2]，其表现为白带不同程度的增多、且白带呈豆腐渣样或凝乳样形态改变，外阴及阴道内有一定程度的灼烧感、或伴有严重瘙痒、尿频、尿痛、性交痛[3]。如何的有效治疗并防止其复发，是目前的研究热点。本次研究评估中药内服联合外洗治疗复发性霉菌性阴道炎的临床效果，现报道如下。
1 资料与方法
1.1一般资料 选取黑龙江省佳木斯中医院2016年5月～2018年5月收治的102例确诊为复发性霉菌性阴道炎并且就医至少2次的患者作为研究对象。所有患者均已婚，剔除肝肾心脏损害性疾病者，患者自愿参加且签署知情同意书。按患者按照随机数字法分为对照组和治疗组，各51例。对照组年龄24～55岁，平均年龄(34.21±4.02)岁，就医次数2～4次，平均就医次数(2.50±0.21)次;治疗组年龄23～53岁，平均年龄(33.79±4.23)岁，就医次数2～4次，平均就医次数(2.46±0.06)次。两组患者一般资料比较，差异无统计学意义(P>0.05)。, 百拇医药(姜佰凤)
关键词：复发性霉菌性阴道炎;加味桂芍四妙汤;制霉菌素
中图分类号：R271.9 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.03.055
, 百拇医药
文章编号：1006-1959(2019)03-0165-02
Abstract：Objective To investigate the therapeutic effect of Chinese herbal medicine combined with external washing on recurrent fungal vaginitis. Methods A total of 102 patients with recurrent vaginitis admitted to our hospital from May 2015 to May 2017 were randomly divided into control group and treatment group， 51 cases each. The control group was treated with nystatin vaginal suppository combined with oral nystatin. The treatment group was treated with Jiawei Guishao Simiao Decoction combined with external Chinese medicine treatment. The therapeutic effects of the two groups were compared. The recurrence of the two groups was followed up.Results The total effective rate was 92.17% in the treatment group， which was higher than that in the control group 82.35%，the difference was statistically significant (P<0.05).At the follow-up， 3 patients (5.89%) relapsed in the control group and 1 patient (1.96%) in the treatment group，the difference was statistically significant (P<0.05).Conclusion TCM oral administration combined with external washing for recurrent mycotic vaginitis has a good clinical effect and low recurrence rate， which is worthy of application.
, 百拇医药
Key words：Recurrent fungal vaginitis;Jiawei Guishao Simiao Decoction;Nystatin
霉菌性陰道炎(vulvoaginal Candidasis，VVC)在临床上比较常见，约75%的女性一生中至少发病一次[1]。其发生的原因多与患者的年龄、性生活情况、妊娠状态、存在糖尿病病史、日常滥用抗生素等有一定程度的关系。医学上将经临床治疗后临床症状及体征消失，真菌检查阴性后又出现真菌学以证实的症状称为复发，若1年内发作4次或以上称复发性霉菌性阴道炎[1，2]，其表现为白带不同程度的增多、且白带呈豆腐渣样或凝乳样形态改变，外阴及阴道内有一定程度的灼烧感、或伴有严重瘙痒、尿频、尿痛、性交痛[3]。如何的有效治疗并防止其复发，是目前的研究热点。本次研究评估中药内服联合外洗治疗复发性霉菌性阴道炎的临床效果，现报道如下。
1 资料与方法
1.1一般资料 选取黑龙江省佳木斯中医院2016年5月～2018年5月收治的102例确诊为复发性霉菌性阴道炎并且就医至少2次的患者作为研究对象。所有患者均已婚，剔除肝肾心脏损害性疾病者，患者自愿参加且签署知情同意书。按患者按照随机数字法分为对照组和治疗组，各51例。对照组年龄24～55岁，平均年龄(34.21±4.02)岁，就医次数2～4次，平均就医次数(2.50±0.21)次;治疗组年龄23～53岁，平均年龄(33.79±4.23)岁，就医次数2～4次，平均就医次数(2.46±0.06)次。两组患者一般资料比较，差异无统计学意义(P>0.05)。, 百拇医药(姜佰凤)